Affinity Data by PubMed id=21420862

PubMed code 21420862

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10880 (AZA \| AZA2 \| AZM acetazolamide \| Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Sassari Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 after 6 hrs by Lineweaver-Burk plot analysis				Bioorg Med Chem Lett 21: 2515-20 (2011) Article DOI: 10.1016/j.bmcl.2011.02.059 BindingDB Entry DOI: 10.7270/Q23R0T59
Universit£ di Sassari Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM10880 (AZA \| AZA2 \| AZM acetazolamide \| Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Sassari Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 after 6 hrs by Lineweaver-Burk plot analysis				Bioorg Med Chem Lett 21: 2515-20 (2011) Article DOI: 10.1016/j.bmcl.2011.02.059 BindingDB Entry DOI: 10.7270/Q23R0T59
Universit£ di Sassari Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50340339 (3,3,3-trifluoro-2,2-dihydroxy-1-p-tolylpropan-1-on...) Show SMILES Cc1ccc(cc1)C(=O)C(O)(O)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Sassari Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 after 6 hrs by Lineweaver-Burk plot analysis				Bioorg Med Chem Lett 21: 2515-20 (2011) Article DOI: 10.1016/j.bmcl.2011.02.059 BindingDB Entry DOI: 10.7270/Q23R0T59
Universit£ di Sassari Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50340339 (3,3,3-trifluoro-2,2-dihydroxy-1-p-tolylpropan-1-on...) Show SMILES Cc1ccc(cc1)C(=O)C(O)(O)C(F)(F)F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	4.10E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Sassari Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 after 6 hrs by Lineweaver-Burk plot analysis				Bioorg Med Chem Lett 21: 2515-20 (2011) Article DOI: 10.1016/j.bmcl.2011.02.059 BindingDB Entry DOI: 10.7270/Q23R0T59
Universit£ di Sassari Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%