Affinity Data by PubMed id=21435888

PubMed code 21435888

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein kinase C alpha type (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Procter& Gamble Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human PKCalpha activity using kemptide as a substrate in presence of 50 uM ATP by mass spectrometry				Bioorg Med Chem 19: 2742-50 (2011) Article DOI: 10.1016/j.bmc.2011.02.036 BindingDB Entry DOI: 10.7270/Q2G44R8J
Procter& Gamble Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit beta (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Procter& Gamble Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of PKA activity using neurogranin as a substrate in presence of 50 uM ATP by mass spectrometry				Bioorg Med Chem 19: 2742-50 (2011) Article DOI: 10.1016/j.bmc.2011.02.036 BindingDB Entry DOI: 10.7270/Q2G44R8J
Procter& Gamble Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50342212 (1-[1-(3-Dimethylaminopropyl)-1H-indol-3-yl]-3-(4-p...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Procter& Gamble Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human PKCalpha activity using kemptide as a substrate in presence of 50 uM ATP by mass spectrometry				Bioorg Med Chem 19: 2742-50 (2011) Article DOI: 10.1016/j.bmc.2011.02.036 BindingDB Entry DOI: 10.7270/Q2G44R8J
Procter& Gamble Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50342213 (1-[1-(3-Diethylaminopropyl)-1H-indol-3-yl]-3-(6-ph...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Procter& Gamble Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human PKCalpha activity using kemptide as a substrate in presence of 50 uM ATP by mass spectrometry				Bioorg Med Chem 19: 2742-50 (2011) Article DOI: 10.1016/j.bmc.2011.02.036 BindingDB Entry DOI: 10.7270/Q2G44R8J
Procter& Gamble Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50342214 (1-[1-(3-Diethylaminopropyl)-1H-indol-3-yl]-3-(2-ph...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Procter& Gamble Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human PKCalpha activity using kemptide as a substrate in presence of 50 uM ATP by mass spectrometry				Bioorg Med Chem 19: 2742-50 (2011) Article DOI: 10.1016/j.bmc.2011.02.036 BindingDB Entry DOI: 10.7270/Q2G44R8J
Procter& Gamble Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50342215 (1-[1-(3-Diethylaminopropyl)-1H-indol-3-yl]-3-(6-ph...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Procter& Gamble Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human PKCalpha activity using kemptide as a substrate in presence of 50 uM ATP by mass spectrometry				Bioorg Med Chem 19: 2742-50 (2011) Article DOI: 10.1016/j.bmc.2011.02.036 BindingDB Entry DOI: 10.7270/Q2G44R8J
Procter& Gamble Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit beta (Homo sapiens (Human))	BDBM50342212 (1-[1-(3-Dimethylaminopropyl)-1H-indol-3-yl]-3-(4-p...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Procter& Gamble Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of PKA activity using neurogranin as a substrate in presence of 50 uM ATP by mass spectrometry				Bioorg Med Chem 19: 2742-50 (2011) Article DOI: 10.1016/j.bmc.2011.02.036 BindingDB Entry DOI: 10.7270/Q2G44R8J
Procter& Gamble Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%