BindingDB logo
myBDB logout

PubMed code 21438571

Compile data set for download or QSAR
Found 28 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM33154
PNG
(4-[(2-benzoxybenzyl)amino]phenol | 4-[(2-phenylmet...)
Show SMILES Oc1ccc(NCc2ccccc2OCc2ccccc2)cc1
Show InChI InChI=1S/C20H19NO2/c22-19-12-10-18(11-13-19)21-14-17-8-4-5-9-20(17)23-15-16-6-2-1-3-7-16/h1-13,21-22H,14-15H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.10E+3n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343395
PNG
(10-(cyclohexylamino)-12-[(2-hydroxyethyl)amino]-15...)
Show SMILES OCCN=C1CC(NC2CCCCC2)c2c(O)c3ccccc3c3onc1c23 |w:3.2|
Show InChI InChI=1S/C22H25N3O3/c26-11-10-23-17-12-16(24-13-6-2-1-3-7-13)18-19-20(17)25-28-22(19)15-9-5-4-8-14(15)21(18)27/h4-5,8-9,13,16,24,26-27H,1-3,6-7,10-12H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.41E+4n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM80984
PNG
(4-chloranyl-2-(5-chloranyl-2-oxidanyl-phenyl)sulfa...)
Show SMILES Oc1ccc(Cl)cc1Sc1cc(Cl)ccc1O
Show InChI InChI=1S/C12H8Cl2O2S/c13-7-1-3-9(15)11(5-7)17-12-6-8(14)2-4-10(12)16/h1-6,15-16H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.85E+4n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343412
PNG
(4-[5-(4-bromophenyl)-4-phenyl-1H-imidazol-2-yl]-2,...)
Show SMILES COc1cc(cc(OC)c1O)-c1nc(c([nH]1)-c1ccc(Br)cc1)-c1ccccc1
Show InChI InChI=1S/C23H19BrN2O3/c1-28-18-12-16(13-19(29-2)22(18)27)23-25-20(14-6-4-3-5-7-14)21(26-23)15-8-10-17(24)11-9-15/h3-13,27H,1-2H3,(H,25,26)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 9.12E+4n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343393
PNG
(CHEMBL1397338 | N-(9-(3,4-dimethoxyphenylamino)-5,...)
Show SMILES CCOc1ccccc1C(=O)Nc1ccc2nc3CCCCc3c(Nc3ccc(OC)c(OC)c3)c2c1
Show InChI InChI=1S/C30H31N3O4/c1-4-37-26-12-8-6-10-22(26)30(34)32-19-13-15-25-23(17-19)29(21-9-5-7-11-24(21)33-25)31-20-14-16-27(35-2)28(18-20)36-3/h6,8,10,12-18H,4-5,7,9,11H2,1-3H3,(H,31,33)(H,32,34)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.06E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343399
PNG
(CHEMBL1609632 | N-[6-(benzylamino)-1,3-dimethyl-2-...)
Show SMILES Cn1c2cc(NCc3ccccc3)c(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)cc2n(C)c1=O
Show InChI InChI=1S/C26H30N4O3S/c1-26(2,3)19-11-13-20(14-12-19)34(32,33)28-22-16-24-23(29(4)25(31)30(24)5)15-21(22)27-17-18-9-7-6-8-10-18/h6-16,27-28H,17H2,1-5H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.32E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343400
PNG
((4-tert-butyl-6-{2-methyl-5H,6H-pyrazolo[1,5-c]qui...)
Show SMILES Cc1cc2-c3ccccc3NC(c3cc(c(O)cc3O)C(C)(C)C)n2n1
Show InChI InChI=1S/C21H23N3O2/c1-12-9-17-13-7-5-6-8-16(13)22-20(24(17)23-12)14-10-15(21(2,3)4)19(26)11-18(14)25/h5-11,20,22,25-26H,1-4H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.38E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343396
PNG
(CHEMBL1551959 | ethyl 4-(4-(dimethylamino)phenylam...)
Show SMILES CCOC(=O)c1cnc2c(ccc3ccccc23)c1Nc1ccc(cc1)N(C)C
Show InChI InChI=1S/C24H23N3O2/c1-4-29-24(28)21-15-25-22-19-8-6-5-7-16(19)9-14-20(22)23(21)26-17-10-12-18(13-11-17)27(2)3/h5-15H,4H2,1-3H3,(H,25,26)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.39E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343402
PNG
(CHEMBL1599158 | N-(4-(dimethylamino)phenyl)-2-(4-(...)
Show SMILES CN(C)c1ccc(NC(=O)CSc2nc(cc(n2)C(F)(F)F)-c2ccco2)cc1
Show InChI InChI=1S/C19H17F3N4O2S/c1-26(2)13-7-5-12(6-8-13)23-17(27)11-29-18-24-14(15-4-3-9-28-15)10-16(25-18)19(20,21)22/h3-10H,11H2,1-2H3,(H,23,27)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.40E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343388
PNG
(7-((2-fluorophenyl)(4-methylpyridin-2-ylamino)meth...)
Show SMILES Cc1ccnc(NC(c2ccccc2F)c2ccc3cccnc3c2O)c1
Show InChI InChI=1S/C22H18FN3O/c1-14-10-12-24-19(13-14)26-21(16-6-2-3-7-18(16)23)17-9-8-15-5-4-11-25-20(15)22(17)27/h2-13,21,27H,1H3,(H,24,26)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.57E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343403
PNG
(4-methoxy-N-(1-(2-(4-methoxyphenoxy)ethyl)-1H-benz...)
Show SMILES COc1ccc(OCCn2c(NC(=O)c3ccc(OC)cc3)nc3ccccc23)cc1
Show InChI InChI=1S/C24H23N3O4/c1-29-18-9-7-17(8-10-18)23(28)26-24-25-21-5-3-4-6-22(21)27(24)15-16-31-20-13-11-19(30-2)12-14-20/h3-14H,15-16H2,1-2H3,(H,25,26,28)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.69E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343411
PNG
(CHEMBL1488419 | N-(2-methoxy-5-methylphenyl)-4-met...)
Show SMILES COc1ccc(C)cc1N(CC(=O)N1CCC(C)CC1)S(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C23H30N2O4S/c1-17-5-8-20(9-6-17)30(27,28)25(21-15-19(3)7-10-22(21)29-4)16-23(26)24-13-11-18(2)12-14-24/h5-10,15,18H,11-14,16H2,1-4H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.75E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343391
PNG
(2-(4-chlorophenyl)-3-hydroxy-6-methyl-4H-chromen-4...)
Show SMILES Cc1ccc2oc(-c3ccc(Cl)cc3)c(O)c(=O)c2c1
Show InChI InChI=1S/C16H11ClO3/c1-9-2-7-13-12(8-9)14(18)15(19)16(20-13)10-3-5-11(17)6-4-10/h2-8,19H,1H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.95E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343406
PNG
(2-(2,4-dimethoxyphenylamino)-N-(3-(4-(2-fluorophen...)
Show SMILES COc1ccc(Nc2cc(C(=O)NCCCN3CCN(CC3)c3ccccc3F)c3ccccc3n2)c(OC)c1
Show InChI InChI=1S/C31H34FN5O3/c1-39-22-12-13-27(29(20-22)40-2)35-30-21-24(23-8-3-5-10-26(23)34-30)31(38)33-14-7-15-36-16-18-37(19-17-36)28-11-6-4-9-25(28)32/h3-6,8-13,20-21H,7,14-19H2,1-2H3,(H,33,38)(H,34,35)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343389
PNG
(6-(2-(4-fluorophenylamino)-4-(4-(pyrrolidin-1-ylsu...)
Show SMILES OCCCCCCN1C(Nc2ccc(F)cc2)SC=C1c1ccc(cc1)S(=O)(=O)N1CCCC1 |c:19|
Show InChI InChI=1S/C25H32FN3O3S2/c26-21-9-11-22(12-10-21)27-25-29(17-3-1-2-6-18-30)24(19-33-25)20-7-13-23(14-8-20)34(31,32)28-15-4-5-16-28/h7-14,19,25,27,30H,1-6,15-18H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343387
PNG
(6-chloro-N-(4-fluorophenyl)-2-(pyridin-2-yl)imidaz...)
Show SMILES Fc1ccc(Nc2c(nc3ccc(Cl)cn23)-c2ccccn2)cc1
Show InChI InChI=1S/C18H12ClFN4/c19-12-4-9-16-23-17(15-3-1-2-10-21-15)18(24(16)11-12)22-14-7-5-13(20)6-8-14/h1-11,22H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343409
PNG
(1-(2-(3,4-dimethoxyphenylamino)allyl)-3-(4-ethylbe...)
Show SMILES CCc1ccc(cc1)C(=O)c1cn(CC(C)=Nc2ccc(OC)c(OC)c2)c2ccccc2c1=O |w:16.17|
Show InChI InChI=1S/C29H28N2O4/c1-5-20-10-12-21(13-11-20)28(32)24-18-31(25-9-7-6-8-23(25)29(24)33)17-19(2)30-22-14-15-26(34-3)27(16-22)35-4/h6-16,18H,5,17H2,1-4H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343410
PNG
(7-(4-chlorobenzyl)-8-((4-(4-methoxyphenyl)piperazi...)
Show SMILES COc1ccc(cc1)N1CCN(Cc2nc3n(C)c(=O)[nH]c(=O)c3n2Cc2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C25H27ClN6O3/c1-29-23-22(24(33)28-25(29)34)32(15-17-3-5-18(26)6-4-17)21(27-23)16-30-11-13-31(14-12-30)19-7-9-20(35-2)10-8-19/h3-10H,11-16H2,1-2H3,(H,28,33,34)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343398
PNG
(5-bromo-2-(5-(o-tolylamino)imidazo[2,1-b]thiazol-6...)
Show SMILES Cc1ccccc1Nc1c(nc2sccn12)-c1ccc(Br)cc1O
Show InChI InChI=1S/C18H14BrN3OS/c1-11-4-2-3-5-14(11)20-17-16(21-18-22(17)8-9-24-18)13-7-6-12(19)10-15(13)23/h2-10,20,23H,1H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343392
PNG
(4-(6-chloro-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl...)
Show SMILES COc1cc(ccc1O)-c1nc2ccc(Cl)cn2c1Nc1ccc2OCCOc2c1
Show InChI InChI=1S/C22H18ClN3O4/c1-28-18-10-13(2-5-16(18)27)21-22(26-12-14(23)3-7-20(26)25-21)24-15-4-6-17-19(11-15)30-9-8-29-17/h2-7,10-12,24,27H,8-9H2,1H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343407
PNG
(2-(3-(3,4-dimethoxystyryl)-1-phenyl-1H-1,2,4-triaz...)
Show SMILES COc1ccc(\C=C\c2nc(-c3ccccc3O)n(n2)-c2ccccc2)cc1OC
Show InChI InChI=1S/C24H21N3O3/c1-29-21-14-12-17(16-22(21)30-2)13-15-23-25-24(19-10-6-7-11-20(19)28)27(26-23)18-8-4-3-5-9-18/h3-16,28H,1-2H3/b15-13+
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343408
PNG
(2-cyclohexyl-3-oxo-N-(3,4,5-trimethoxyphenyl)isoin...)
Show SMILES COc1cc(NC(=O)c2cccc3CN(C4CCCCC4)C(=O)c23)cc(OC)c1OC
Show InChI InChI=1S/C24H28N2O5/c1-29-19-12-16(13-20(30-2)22(19)31-3)25-23(27)18-11-7-8-15-14-26(24(28)21(15)18)17-9-5-4-6-10-17/h7-8,11-13,17H,4-6,9-10,14H2,1-3H3,(H,25,27)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343394
PNG
(CHEMBL1774935 | methyl 2-(2-(4-fluorophenyl)-8-met...)
Show SMILES COC(=O)CC1Oc2ccc(C)cc2-n2cc(nc12)-c1ccc(F)cc1
Show InChI InChI=1S/C20H17FN2O3/c1-12-3-8-17-16(9-12)23-11-15(13-4-6-14(21)7-5-13)22-20(23)18(26-17)10-19(24)25-2/h3-9,11,18H,10H2,1-2H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343390
PNG
(4-methoxy-N-((1-(2-(p-tolyloxy)ethyl)-1H-benzo[d]i...)
Show SMILES COc1ccc(NCc2nc3ccccc3n2CCOc2ccc(C)cc2)cc1
Show InChI InChI=1S/C24H25N3O2/c1-18-7-11-21(12-8-18)29-16-15-27-23-6-4-3-5-22(23)26-24(27)17-25-19-9-13-20(28-2)14-10-19/h3-14,25H,15-17H2,1-2H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343404
PNG
(4-bromo-2-(3-(3,4-dimethoxyphenylamino)imidazo[1,2...)
Show SMILES COc1ccc(Nc2c(nc3ncccn23)-c2cc(Br)ccc2O)cc1OC
Show InChI InChI=1S/C20H17BrN4O3/c1-27-16-7-5-13(11-17(16)28-2)23-19-18(14-10-12(21)4-6-15(14)26)24-20-22-8-3-9-25(19)20/h3-11,23,26H,1-2H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343397
PNG
(CHEMBL1358481 | N2,N4-bis(2,4-dimethoxyphenyl)-6-m...)
Show SMILES COc1ccc(Nc2nc(Nc3ccc(OC)cc3OC)nc(n2)N2CCOCC2)c(OC)c1
Show InChI InChI=1S/C23H28N6O5/c1-30-15-5-7-17(19(13-15)32-3)24-21-26-22(28-23(27-21)29-9-11-34-12-10-29)25-18-8-6-16(31-2)14-20(18)33-4/h5-8,13-14H,9-12H2,1-4H3,(H2,24,25,26,27,28)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343405
PNG
(6-(9-chloro-4-(4-fluorophenyl)-5H-chromeno[4,3-b]p...)
Show SMILES OC1COc2ccc(cc2N1)-c1cc(-c2ccc(F)cc2)c2COc3ccc(Cl)cc3-c2n1
Show InChI InChI=1S/C26H18ClFN2O3/c27-16-4-8-23-19(10-16)26-20(12-32-23)18(14-1-5-17(28)6-2-14)11-21(30-26)15-3-7-24-22(9-15)29-25(31)13-33-24/h1-11,25,29,31H,12-13H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343401
PNG
((4R)-4-(2-chlorophenyl)-8-ethoxy-3a,4,5,9b-tetrahy...)
Show SMILES CCOc1ccc2N[C@H](C3C=CCC3c2c1)c1ccccc1Cl |r,c:10|
Show InChI InChI=1S/C20H20ClNO/c1-2-23-13-10-11-19-17(12-13)14-7-5-8-15(14)20(22-19)16-6-3-4-9-18(16)21/h3-6,8-12,14-15,20,22H,2,7H2,1H3/t14?,15?,20-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.21E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%