Affinity Data by PubMed id=21548579

PubMed code 21548579

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50345577 (CHEMBL1782082 \| Hippolide A) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of recombinant PTP1B catalytic domain using pNPP as substrate assessed as pNP release				J Nat Prod 74: 1248-54 (2011) Article DOI: 10.1021/np200227s BindingDB Entry DOI: 10.7270/Q2571CCF
Second Military Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50345576 (CHEMBL1784622 \| Hippolide B) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of recombinant PTP1B catalytic domain using pNPP as substrate assessed as pNP release				J Nat Prod 74: 1248-54 (2011) Article DOI: 10.1021/np200227s BindingDB Entry DOI: 10.7270/Q2571CCF
Second Military Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50345578 (CHEMBL1784623 \| Hippolide E) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Binding affinity at PKCalpha after 1 hr by luminescent kinase assay				J Nat Prod 74: 1248-54 (2011) Article DOI: 10.1021/np200227s BindingDB Entry DOI: 10.7270/Q2571CCF
Second Military Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C gamma type (Homo sapiens (Human))	BDBM50345577 (CHEMBL1782082 \| Hippolide A) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Binding affinity at PKCgamma after 1 hr by luminescent kinase assay				J Nat Prod 74: 1248-54 (2011) Article DOI: 10.1021/np200227s BindingDB Entry DOI: 10.7270/Q2571CCF
Second Military Medical University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%