Affinity Data by PubMed id=21635211

PubMed code 21635211

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM235679 ((2-Bromo-3,4-dihydroxyphenyl)(2,3-dibromo-4,5-dihy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Atat�rk University					Assay Description Carbonic anhydrase activity was assayed by following the hydration of CO2 according to our previous studies [Soyut et al., Protein Pept. Lett., 15:52...				J Enzyme Inhib Med Chem 27: 43-50 (2012) Article DOI: 10.3109/14756366.2011.574131 BindingDB Entry DOI: 10.7270/Q2CR5S75
Atat�rk University					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM235681 ((2-Bromo-4,5-dihydroxyphenyl)(2,5-dibromo-3,4-dihy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Atat�rk University					Assay Description Carbonic anhydrase activity was assayed by following the hydration of CO2 according to our previous studies [Soyut et al., Protein Pept. Lett., 15:52...				J Enzyme Inhib Med Chem 27: 43-50 (2012) Article DOI: 10.3109/14756366.2011.574131 BindingDB Entry DOI: 10.7270/Q2CR5S75
Atat�rk University					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM235678 ((2-Bromo-3,4-dihydroxyphenyl)(2-bromo-4,5-dihydrox...) Show SMILES Oc1ccc(C(=O)c2cc(O)c(O)cc2Br)c(Br)c1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Atat�rk University					Assay Description Carbonic anhydrase activity was assayed by following the hydration of CO2 according to our previous studies [Soyut et al., Protein Pept. Lett., 15:52...				J Enzyme Inhib Med Chem 27: 43-50 (2012) Article DOI: 10.3109/14756366.2011.574131 BindingDB Entry DOI: 10.7270/Q2CR5S75
Atat�rk University					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM235680 ((2-Bromo-4,5-dihydroxyphenyl)(2,6-dibromo-3,4-dime...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Atat�rk University					Assay Description Carbonic anhydrase activity was assayed by following the hydration of CO2 according to our previous studies [Soyut et al., Protein Pept. Lett., 15:52...				J Enzyme Inhib Med Chem 27: 43-50 (2012) Article DOI: 10.3109/14756366.2011.574131 BindingDB Entry DOI: 10.7270/Q2CR5S75
Atat�rk University					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM235674 ((2-Bromo-3,4-dimethoxyphenyl)(2-bromo-4,5-dimethox...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Atat�rk University					Assay Description Carbonic anhydrase activity was assayed by following the hydration of CO2 according to our previous studies [Soyut et al., Protein Pept. Lett., 15:52...				J Enzyme Inhib Med Chem 27: 43-50 (2012) Article DOI: 10.3109/14756366.2011.574131 BindingDB Entry DOI: 10.7270/Q2CR5S75
Atat�rk University					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM235672 ((2-bromo-3,4-dihydroxyphenyl)(3,4-dihydroxyphenyl)...) Show SMILES Oc1ccc(cc1O)C(=O)c1ccc(O)c(O)c1Br Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
Atat�rk University					Assay Description Carbonic anhydrase activity was assayed by following the hydration of CO2 according to our previous studies [Soyut et al., Protein Pept. Lett., 15:52...				J Enzyme Inhib Med Chem 27: 43-50 (2012) Article DOI: 10.3109/14756366.2011.574131 BindingDB Entry DOI: 10.7270/Q2CR5S75
Atat�rk University					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50363494 (5,5'-methylenebis(3,4,6-tribromo-benzene-1,2-d...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
Atat�rk University					Assay Description Carbonic anhydrase activity was assayed by following the hydration of CO2 according to our previous studies [Soyut et al., Protein Pept. Lett., 15:52...				J Enzyme Inhib Med Chem 27: 43-50 (2012) Article DOI: 10.3109/14756366.2011.574131 BindingDB Entry DOI: 10.7270/Q2CR5S75
Atat�rk University					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM235675 ((2-Bromo-3,4-dimethoxyphenyl)(2,3-dibromo-4,5-dime...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
Atat�rk University					Assay Description Carbonic anhydrase activity was assayed by following the hydration of CO2 according to our previous studies [Soyut et al., Protein Pept. Lett., 15:52...				J Enzyme Inhib Med Chem 27: 43-50 (2012) Article DOI: 10.3109/14756366.2011.574131 BindingDB Entry DOI: 10.7270/Q2CR5S75
Atat�rk University					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM235677 ((2-Bromo-4,5-dimethoxyphenyl)(2,5-dibromo-3,4-dime...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Atat�rk University					Assay Description Carbonic anhydrase activity was assayed by following the hydration of CO2 according to our previous studies [Soyut et al., Protein Pept. Lett., 15:52...				J Enzyme Inhib Med Chem 27: 43-50 (2012) Article DOI: 10.3109/14756366.2011.574131 BindingDB Entry DOI: 10.7270/Q2CR5S75
Atat�rk University					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50363493 (3,4,6-tribromo-5-(2,5-dibromo-3,4-dihydroxybenzyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
Atat�rk University					Assay Description Carbonic anhydrase activity was assayed by following the hydration of CO2 according to our previous studies [Soyut et al., Protein Pept. Lett., 15:52...				J Enzyme Inhib Med Chem 27: 43-50 (2012) Article DOI: 10.3109/14756366.2011.574131 BindingDB Entry DOI: 10.7270/Q2CR5S75
Atat�rk University					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM235676 ((2-Bromo-4,5-dimethoxyphenyl)(2,6-dibromo-3,4-dime...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.26E+5	n/a	n/a	n/a	n/a	n/a	n/a
Atat�rk University					Assay Description Carbonic anhydrase activity was assayed by following the hydration of CO2 according to our previous studies [Soyut et al., Protein Pept. Lett., 15:52...				J Enzyme Inhib Med Chem 27: 43-50 (2012) Article DOI: 10.3109/14756366.2011.574131 BindingDB Entry DOI: 10.7270/Q2CR5S75
Atat�rk University					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM235673 ((2-bromo-3,4-dimethoxyphenyl)(3,4-dimethoxyphenyl)...) Show SMILES COc1ccc(cc1OC)C(=O)c1ccc(OC)c(OC)c1Br Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.72E+5	n/a	n/a	n/a	n/a	n/a	n/a
Atat�rk University					Assay Description Carbonic anhydrase activity was assayed by following the hydration of CO2 according to our previous studies [Soyut et al., Protein Pept. Lett., 15:52...				J Enzyme Inhib Med Chem 27: 43-50 (2012) Article DOI: 10.3109/14756366.2011.574131 BindingDB Entry DOI: 10.7270/Q2CR5S75
Atat�rk University					More data for this Ligand-Target Pair

* indicates data uncertainty>20%