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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50357677 (CHEMBL1914951) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL | Assay Description Competitive inhibition of human topoisomerase-2 alpha-ATPase activity by Lineweaver-Burk assay in presence of 200 to 520 uM ATP | J Med Chem 54: 5013-30 (2011) Article DOI: 10.1021/jm200235u BindingDB Entry DOI: 10.7270/Q25T3KW8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50357677 (CHEMBL1914951) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL | Assay Description Inhibition of human topoisomerase 2 alpha-mediated decatenation of kDNA by agarose gel electrophoresis | J Med Chem 54: 5013-30 (2011) Article DOI: 10.1021/jm200235u BindingDB Entry DOI: 10.7270/Q25T3KW8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
