Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
dCTP pyrophosphatase 1 (Homo sapiens (Human)) | BDBM85128 (Triptriolide, 5) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 8.50E+4 | -23.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Yale University | Assay Description Kinetic enzyme assays were performed in a 384-well, white plates (Nunc) on a Wallac Victor 2 plate reader using human DCTPP1 and triptolide and analo... | Chembiochem 12: 1767-73 (2011) Article DOI: 10.1002/cbic.201100007 BindingDB Entry DOI: 10.7270/Q2125R69 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
dCTP pyrophosphatase 1 (Homo sapiens (Human)) | BDBM85127 (Triptonide, 4) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 1.35E+5 | -22.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Yale University | Assay Description Kinetic enzyme assays were performed in a 384-well, white plates (Nunc) on a Wallac Victor 2 plate reader using human DCTPP1 and triptolide and analo... | Chembiochem 12: 1767-73 (2011) Article DOI: 10.1002/cbic.201100007 BindingDB Entry DOI: 10.7270/Q2125R69 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
dCTP pyrophosphatase 1 (Homo sapiens (Human)) | BDBM50241049 (CHEMBL463763 | Triptolide, 1 | triptolide) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 1.68E+5 | -21.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Yale University | Assay Description Kinetic enzyme assays were performed in a 384-well, white plates (Nunc) on a Wallac Victor 2 plate reader using human DCTPP1 and triptolide and analo... | Chembiochem 12: 1767-73 (2011) Article DOI: 10.1002/cbic.201100007 BindingDB Entry DOI: 10.7270/Q2125R69 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
dCTP pyrophosphatase 1 (Homo sapiens (Human)) | BDBM85130 (14-alpha-triptolide, 7) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 1.94E+5 | -21.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Yale University | Assay Description Kinetic enzyme assays were performed in a 384-well, white plates (Nunc) on a Wallac Victor 2 plate reader using human DCTPP1 and triptolide and analo... | Chembiochem 12: 1767-73 (2011) Article DOI: 10.1002/cbic.201100007 BindingDB Entry DOI: 10.7270/Q2125R69 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
dCTP pyrophosphatase 1 (Homo sapiens (Human)) | BDBM85129 (5-Hydroxytriptonide, 6) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 3.56E+5 | -19.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Yale University | Assay Description Kinetic enzyme assays were performed in a 384-well, white plates (Nunc) on a Wallac Victor 2 plate reader using human DCTPP1 and triptolide and analo... | Chembiochem 12: 1767-73 (2011) Article DOI: 10.1002/cbic.201100007 BindingDB Entry DOI: 10.7270/Q2125R69 | |||||||||||
More data for this Ligand-Target Pair |