Found 24 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348263
(CHEMBL1800693)Show SMILES CC(C)(C)c1csc(NC(=O)N2CCCN(CC2)c2ncc(cc2Cl)C(F)(F)F)n1 Show InChI InChI=1S/C19H23ClF3N5OS/c1-18(2,3)14-11-30-16(25-14)26-17(29)28-6-4-5-27(7-8-28)15-13(20)9-12(10-24-15)19(21,22)23/h9-11H,4-8H2,1-3H3,(H,25,26,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348273
(CHEMBL1800752)Show SMILES CC(C)(C)c1ccc2oc(nc2c1)N1CCCN(CC1)C(=O)N1CCOCC1 Show InChI InChI=1S/C21H30N4O3/c1-21(2,3)16-5-6-18-17(15-16)22-19(28-18)23-7-4-8-24(10-9-23)20(26)25-11-13-27-14-12-25/h5-6,15H,4,7-14H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348269
(CHEMBL1800746)Show SMILES CC(C)(C)c1cc(NC(=O)N2CCCN(CC2)c2ccc(cn2)C#N)no1 Show InChI InChI=1S/C19H24N6O2/c1-19(2,3)15-11-16(23-27-15)22-18(26)25-8-4-7-24(9-10-25)17-6-5-14(12-20)13-21-17/h5-6,11,13H,4,7-10H2,1-3H3,(H,22,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348270
(CHEMBL1800748)Show SMILES CC(C)(C)c1cc(NC(=O)N2CCCN(CC2)c2cc(ccn2)C#N)no1 Show InChI InChI=1S/C19H24N6O2/c1-19(2,3)15-12-16(23-27-15)22-18(26)25-8-4-7-24(9-10-25)17-11-14(13-20)5-6-21-17/h5-6,11-12H,4,7-10H2,1-3H3,(H,22,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348272
(CHEMBL1800751)Show SMILES CC(C)(C)c1ccc2oc(nc2c1)N1CCCN(CC1)C(=O)C1CCOCC1 Show InChI InChI=1S/C22H31N3O3/c1-22(2,3)17-5-6-19-18(15-17)23-21(28-19)25-10-4-9-24(11-12-25)20(26)16-7-13-27-14-8-16/h5-6,15-16H,4,7-14H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348274
(CHEMBL1800753)Show SMILES CC(C)(C)c1ccc2oc(nc2c1)N1CCCN(CC1)C(=O)N1CCS(=O)(=O)CC1 Show InChI InChI=1S/C21H30N4O4S/c1-21(2,3)16-5-6-18-17(15-16)22-19(29-18)23-7-4-8-24(10-9-23)20(26)25-11-13-30(27,28)14-12-25/h5-6,15H,4,7-14H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348257
(CHEMBL1800743)Show InChI InChI=1S/C18H25N5O2/c1-18(2,3)14-13-15(21-25-14)20-17(24)23-10-6-9-22(11-12-23)16-7-4-5-8-19-16/h4-5,7-8,13H,6,9-12H2,1-3H3,(H,20,21,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348258
(CHEMBL1800747)Show SMILES CC(C)(C)c1cc(NC(=O)N2CCCN(CC2)c2cccc(n2)C#N)no1 Show InChI InChI=1S/C19H24N6O2/c1-19(2,3)15-12-16(23-27-15)22-18(26)25-9-5-8-24(10-11-25)17-7-4-6-14(13-20)21-17/h4,6-7,12H,5,8-11H2,1-3H3,(H,22,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348259
(CHEMBL1800756)Show InChI InChI=1S/C18H22ClN3O2S/c19-14-3-1-4-15-16(14)20-18(25-15)22-8-2-7-21(9-10-22)17(23)13-5-11-24-12-6-13/h1,3-4,13H,2,5-12H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348279
(CHEMBL1800749)Show SMILES CC(C)(C)c1cc(NC(=O)N2CCCN(CC2)c2ncccc2C#N)no1 Show InChI InChI=1S/C19H24N6O2/c1-19(2,3)15-12-16(23-27-15)22-18(26)25-9-5-8-24(10-11-25)17-14(13-20)6-4-7-21-17/h4,6-7,12H,5,8-11H2,1-3H3,(H,22,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348266
(CHEMBL1800742)Show SMILES CC(C)(C)c1ccc2oc(nc2c1)N1CCCN(CC1)c1ncc(cc1Cl)C(F)(F)F Show InChI InChI=1S/C22H24ClF3N4O/c1-21(2,3)14-5-6-18-17(12-14)28-20(31-18)30-8-4-7-29(9-10-30)19-16(23)11-15(13-27-19)22(24,25)26/h5-6,11-13H,4,7-10H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348271
(CHEMBL1800750)Show SMILES CC(C)(C)c1ccc2oc(nc2c1)N1CCCN(CC1)C(=O)CC1CCCC1 Show InChI InChI=1S/C23H33N3O2/c1-23(2,3)18-9-10-20-19(16-18)24-22(28-20)26-12-6-11-25(13-14-26)21(27)15-17-7-4-5-8-17/h9-10,16-17H,4-8,11-15H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348276
(CHEMBL1800755)Show InChI InChI=1S/C18H22ClN3O2S/c19-14-2-3-16-15(12-14)20-18(25-16)22-7-1-6-21(8-9-22)17(23)13-4-10-24-11-5-13/h2-3,12-13H,1,4-11H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 150 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348278
(CHEMBL1800758)Show SMILES FC(F)(F)c1nc(sc1Cl)N1CCCN(CC1)C(=O)C1CCOCC1 Show InChI InChI=1S/C15H19ClF3N3O2S/c16-12-11(15(17,18)19)20-14(25-12)22-5-1-4-21(6-7-22)13(23)10-2-8-24-9-3-10/h10H,1-9H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348261
(CHEMBL1800691)Show SMILES CC(C)(C)c1cc(NC(=O)N2CCCN(CC2)c2ncc(cc2Cl)C(F)(F)F)no1 Show InChI InChI=1S/C19H23ClF3N5O2/c1-18(2,3)14-10-15(26-30-14)25-17(29)28-6-4-5-27(7-8-28)16-13(20)9-12(11-24-16)19(21,22)23/h9-11H,4-8H2,1-3H3,(H,25,26,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348275
(CHEMBL1800754)Show InChI InChI=1S/C18H22ClN3O2S/c19-14-2-3-15-16(12-14)25-18(20-15)22-7-1-6-21(8-9-22)17(23)13-4-10-24-11-5-13/h2-3,12-13H,1,4-11H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 62 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348267
(CHEMBL1800744)Show SMILES CC(C)(C)c1cc(NC(=O)N2CCCN(CC2)c2ncccc2Cl)no1 Show InChI InChI=1S/C18H24ClN5O2/c1-18(2,3)14-12-15(22-26-14)21-17(25)24-9-5-8-23(10-11-24)16-13(19)6-4-7-20-16/h4,6-7,12H,5,8-11H2,1-3H3,(H,21,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 280 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348268
(CHEMBL1800745)Show SMILES CC(C)(C)c1cc(NC(=O)N2CCCN(CC2)c2ccc(cn2)C(F)(F)F)no1 Show InChI InChI=1S/C19H24F3N5O2/c1-18(2,3)14-11-15(25-29-14)24-17(28)27-8-4-7-26(9-10-27)16-6-5-13(12-23-16)19(20,21)22/h5-6,11-12H,4,7-10H2,1-3H3,(H,24,25,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348277
(CHEMBL1800757)Show InChI InChI=1S/C19H24N4O2S/c24-18(16-7-13-25-14-8-16)22-9-4-10-23(12-11-22)19-20-17(21-26-19)15-5-2-1-3-6-15/h1-3,5-6,16H,4,7-14H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348264
(CHEMBL1800694)Show SMILES FC(F)(F)c1cnc(N2CCCN(CC2)c2nc(ns2)-c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C19H17ClF3N5S/c20-15-11-14(19(21,22)23)12-24-17(15)27-7-4-8-28(10-9-27)18-25-16(26-29-18)13-5-2-1-3-6-13/h1-3,5-6,11-12H,4,7-10H2 | PDB
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PubMed
| n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50341023
(CHEMBL1762293 | N-(5-tert-butylisoxazol-3-yl)-4-(t...)Show SMILES CC(C)(C)c1cc(NC(=O)N2CCCN(CC2)C(=O)C2CCOCC2)no1 Show InChI InChI=1S/C19H30N4O4/c1-19(2,3)15-13-16(21-27-15)20-18(25)23-8-4-7-22(9-10-23)17(24)14-5-11-26-12-6-14/h13-14H,4-12H2,1-3H3,(H,20,21,25) | PDB
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| n/a | n/a | n/a | n/a | 67 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348260
(CHEMBL1800690)Show SMILES FC(F)(F)c1cnc(N2CCCN(CC2)C(=O)Nc2ccc(Cl)c(Cl)c2)c(Cl)c1 Show InChI InChI=1S/C18H16Cl3F3N4O/c19-13-3-2-12(9-14(13)20)26-17(29)28-5-1-4-27(6-7-28)16-15(21)8-11(10-25-16)18(22,23)24/h2-3,8-10H,1,4-7H2,(H,26,29) | PDB
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| n/a | n/a | n/a | n/a | 154 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348262
(CHEMBL1800692)Show SMILES Cn1nc(cc1NC(=O)N1CCCN(CC1)c1ncc(cc1Cl)C(F)(F)F)C(C)(C)C Show InChI InChI=1S/C20H26ClF3N6O/c1-19(2,3)15-11-16(28(4)27-15)26-18(31)30-7-5-6-29(8-9-30)17-14(21)10-13(12-25-17)20(22,23)24/h10-12H,5-9H2,1-4H3,(H,26,31) | PDB
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| n/a | n/a | n/a | n/a | 8 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50348265
(CHEMBL1800741)Show SMILES FC(F)(F)c1cnc(N2CCCN(CC2)c2nc3ccc(Cl)cc3s2)c(Cl)c1 Show InChI InChI=1S/C18H15Cl2F3N4S/c19-12-2-3-14-15(9-12)28-17(25-14)27-5-1-4-26(6-7-27)16-13(20)8-11(10-24-16)18(21,22)23/h2-3,8-10H,1,4-7H2 | PDB
Reactome pathway
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PC cid
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| Article
PubMed
| n/a | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production |
Bioorg Med Chem Lett 21: 4276-80 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.068
BindingDB Entry DOI: 10.7270/Q2862GS1 |
More data for this
Ligand-Target Pair | |
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