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PubMed code 21816515

Compile data set for download or QSAR
Found 93 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50366495
PNG
((+)butaclamol | CHEMBL1255588)
Show SMILES CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 |r|
Show InChI InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m1/s1
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 0.5n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354102
PNG
(CHEMBL1836107)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccccc1)c1ccc2ccccc2c1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C25H26N2O/c28-25(21-11-10-19-8-4-5-9-20(19)14-21)26-22-15-23-12-13-24(16-22)27(23)17-18-6-2-1-3-7-18/h1-11,14,22-24H,12-13,15-17H2,(H,26,28)/t23-,24-/m1/s1
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PubMed
 2.5n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM10755
PNG
(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Show SMILES NCCc1c[nH]c2ccc(O)cc12
Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
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 2.60n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM31005
PNG
(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)
Show SMILES Cl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21
Show InChI InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H
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 5n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354098
PNG
(CHEMBL1836061)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C20H28ClN3O3/c1-26-19-10-18(22)17(21)9-16(19)20(25)23-12-7-13-4-5-14(8-12)24(13)11-15-3-2-6-27-15/h9-10,12-15H,2-8,11,22H2,1H3,(H,23,25)/t13-,14-,15?/m1/s1
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 6.20n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50001884
PNG
(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8|
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3
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 8.90n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354103
PNG
(CHEMBL1836108)
Show SMILES COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccccn2)c1OC |r,TLB:9:10:17:13.14|
Show InChI InChI=1S/C22H27N3O3/c1-27-20-8-5-7-19(21(20)28-2)22(26)24-16-12-17-9-10-18(13-16)25(17)14-15-6-3-4-11-23-15/h3-8,11,16-18H,9-10,12-14H2,1-2H3,(H,24,26)/t17-,18-/m1/s1
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 9.30n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354104
PNG
(CHEMBL1836109)
Show SMILES COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2cccnc2)c1OC |r,TLB:9:10:17:13.14|
Show InChI InChI=1S/C22H27N3O3/c1-27-20-7-3-6-19(21(20)28-2)22(26)24-16-11-17-8-9-18(12-16)25(17)14-15-5-4-10-23-13-15/h3-7,10,13,16-18H,8-9,11-12,14H2,1-2H3,(H,24,26)/t17-,18-/m1/s1
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 11.5n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354100
PNG
(CHEMBL1836105)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1)c1ccc2ccccc2c1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C23H28N2O2/c26-23(18-8-7-16-4-1-2-5-17(16)12-18)24-19-13-20-9-10-21(14-19)25(20)15-22-6-3-11-27-22/h1-2,4-5,7-8,12,19-22H,3,6,9-11,13-15H2,(H,24,26)/t20-,21-,22?/m1/s1
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 12.3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354115
PNG
(CHEMBL1836054)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C20H24ClN3O3/c1-26-19-10-18(22)17(21)9-16(19)20(25)23-12-7-13-4-5-14(8-12)24(13)11-15-3-2-6-27-15/h2-3,6,9-10,12-14H,4-5,7-8,11,22H2,1H3,(H,23,25)/t13-,14-/m1/s1
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 16.6n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354115
PNG
(CHEMBL1836054)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C20H24ClN3O3/c1-26-19-10-18(22)17(21)9-16(19)20(25)23-12-7-13-4-5-14(8-12)24(13)11-15-3-2-6-27-15/h2-3,6,9-10,12-14H,4-5,7-8,11,22H2,1H3,(H,23,25)/t13-,14-/m1/s1
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 18.2n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354114
PNG
(CHEMBL1836056)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1)c1ccc2ccccc2c1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C23H24N2O2/c26-23(18-8-7-16-4-1-2-5-17(16)12-18)24-19-13-20-9-10-21(14-19)25(20)15-22-6-3-11-27-22/h1-8,11-12,19-21H,9-10,13-15H2,(H,24,26)/t20-,21-/m1/s1
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 24.1n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354091
PNG
(CHEMBL1836044)
Show SMILES COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccco2)c1OC |r,TLB:9:10:17:13.14|
Show InChI InChI=1S/C21H26N2O4/c1-25-19-7-3-6-18(20(19)26-2)21(24)22-14-11-15-8-9-16(12-14)23(15)13-17-5-4-10-27-17/h3-7,10,14-16H,8-9,11-13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1
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 26.3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354105
PNG
(CHEMBL1836110)
Show SMILES COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccncc2)c1OC |r,TLB:9:10:17:13.14|
Show InChI InChI=1S/C22H27N3O3/c1-27-20-5-3-4-19(21(20)28-2)22(26)24-16-12-17-6-7-18(13-16)25(17)14-15-8-10-23-11-9-15/h3-5,8-11,16-18H,6-7,12-14H2,1-2H3,(H,24,26)/t17-,18-/m1/s1
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 28.3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354102
PNG
(CHEMBL1836107)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccccc1)c1ccc2ccccc2c1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C25H26N2O/c28-25(21-11-10-19-8-4-5-9-20(19)14-21)26-22-15-23-12-13-24(16-22)27(23)17-18-6-2-1-3-7-18/h1-11,14,22-24H,12-13,15-17H2,(H,26,28)/t23-,24-/m1/s1
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 82.4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354098
PNG
(CHEMBL1836061)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C20H28ClN3O3/c1-26-19-10-18(22)17(21)9-16(19)20(25)23-12-7-13-4-5-14(8-12)24(13)11-15-3-2-6-27-15/h9-10,12-15H,2-8,11,22H2,1H3,(H,23,25)/t13-,14-,15?/m1/s1
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 103n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354096
PNG
(CHEMBL1836059)
Show SMILES COc1ccc(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H27ClN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h4,7,9,14-17H,2-3,5-6,8,10-12H2,1H3,(H,22,24)/t15-,16-,17?/m1/s1
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 120n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50001884
PNG
(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8|
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3
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 130n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50001884
PNG
(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8|
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3
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 140n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354111
PNG
(CHEMBL1836052)
Show SMILES COc1cc(Cl)ccc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H23ClN2O3/c1-25-19-9-13(21)4-7-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1
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 174n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354109
PNG
(CHEMBL1836050)
Show SMILES COc1ccc(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H23ClN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1
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 175n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50095890
PNG
(2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperaz...)
Show SMILES OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 |t:13|
Show InChI InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2
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 180n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354114
PNG
(CHEMBL1836056)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1)c1ccc2ccccc2c1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C23H24N2O2/c26-23(18-8-7-16-4-1-2-5-17(16)12-18)24-19-13-20-9-10-21(14-19)25(20)15-22-6-3-11-27-22/h1-8,11-12,19-21H,9-10,13-15H2,(H,24,26)/t20-,21-/m1/s1
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 203n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354109
PNG
(CHEMBL1836050)
Show SMILES COc1ccc(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H23ClN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1
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 218n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50095890
PNG
(2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperaz...)
Show SMILES OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 |t:13|
Show InChI InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2
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 220n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50095890
PNG
(2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperaz...)
Show SMILES OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 |t:13|
Show InChI InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2
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 230n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354102
PNG
(CHEMBL1836107)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccccc1)c1ccc2ccccc2c1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C25H26N2O/c28-25(21-11-10-19-8-4-5-9-20(19)14-21)26-22-15-23-12-13-24(16-22)27(23)17-18-6-2-1-3-7-18/h1-11,14,22-24H,12-13,15-17H2,(H,26,28)/t23-,24-/m1/s1
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 304n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354101
PNG
(CHEMBL1836106)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccccc1)c1cccc2ccccc12 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C25H26N2O/c28-25(24-12-6-10-19-9-4-5-11-23(19)24)26-20-15-21-13-14-22(16-20)27(21)17-18-7-2-1-3-8-18/h1-12,20-22H,13-17H2,(H,26,28)/t21-,22-/m1/s1
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 394n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354099
PNG
(CHEMBL1836104)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1)c1cccc2ccccc12 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C23H28N2O2/c26-23(22-9-3-6-16-5-1-2-8-21(16)22)24-17-13-18-10-11-19(14-17)25(18)15-20-7-4-12-27-20/h1-3,5-6,8-9,17-20H,4,7,10-15H2,(H,24,26)/t18-,19-,20?/m1/s1
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 394n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354110
PNG
(CHEMBL1836051)
Show SMILES COc1ccc(F)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H23FN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1
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 507n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354101
PNG
(CHEMBL1836106)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccccc1)c1cccc2ccccc12 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C25H26N2O/c28-25(24-12-6-10-19-9-4-5-11-23(19)24)26-20-15-21-13-14-22(16-20)27(21)17-18-7-2-1-3-8-18/h1-12,20-22H,13-17H2,(H,26,28)/t21-,22-/m1/s1
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 532n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354092
PNG
(CHEMBL1836045)
Show SMILES COc1ccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccco2)c(OC)c1 |r,TLB:8:9:16:12.13|
Show InChI InChI=1S/C21H26N2O4/c1-25-17-7-8-19(20(12-17)26-2)21(24)22-14-10-15-5-6-16(11-14)23(15)13-18-4-3-9-27-18/h3-4,7-9,12,14-16H,5-6,10-11,13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1
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 653n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354111
PNG
(CHEMBL1836052)
Show SMILES COc1cc(Cl)ccc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H23ClN2O3/c1-25-19-9-13(21)4-7-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1
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 682n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354105
PNG
(CHEMBL1836110)
Show SMILES COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccncc2)c1OC |r,TLB:9:10:17:13.14|
Show InChI InChI=1S/C22H27N3O3/c1-27-20-5-3-4-19(21(20)28-2)22(26)24-16-12-17-6-7-18(13-16)25(17)14-15-8-10-23-11-9-15/h3-5,8-11,16-18H,6-7,12-14H2,1-2H3,(H,24,26)/t17-,18-/m1/s1
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 700n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354091
PNG
(CHEMBL1836044)
Show SMILES COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccco2)c1OC |r,TLB:9:10:17:13.14|
Show InChI InChI=1S/C21H26N2O4/c1-25-19-7-3-6-18(20(19)26-2)21(24)22-14-11-15-8-9-16(12-14)23(15)13-17-5-4-10-27-17/h3-7,10,14-16H,8-9,11-13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1
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 745n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354107
PNG
(CHEMBL1836048 | cid_653771)
Show SMILES COc1cc(OC)cc(c1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C21H26N2O4/c1-25-19-8-14(9-20(12-19)26-2)21(24)22-15-10-16-5-6-17(11-15)23(16)13-18-4-3-7-27-18/h3-4,7-9,12,15-17H,5-6,10-11,13H2,1-2H3,(H,22,24)/t16-,17-/m1/s1
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 929n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354104
PNG
(CHEMBL1836109)
Show SMILES COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2cccnc2)c1OC |r,TLB:9:10:17:13.14|
Show InChI InChI=1S/C22H27N3O3/c1-27-20-7-3-6-19(21(20)28-2)22(26)24-16-11-17-8-9-18(12-16)25(17)14-15-5-4-10-23-13-15/h3-7,10,13,16-18H,8-9,11-12,14H2,1-2H3,(H,24,26)/t17-,18-/m1/s1
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 956n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354103
PNG
(CHEMBL1836108)
Show SMILES COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccccn2)c1OC |r,TLB:9:10:17:13.14|
Show InChI InChI=1S/C22H27N3O3/c1-27-20-8-5-7-19(21(20)28-2)22(26)24-16-12-17-9-10-18(13-16)25(17)14-15-6-3-4-11-23-15/h3-8,11,16-18H,9-10,12-14H2,1-2H3,(H,24,26)/t17-,18-/m1/s1
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 1.00E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354090
PNG
(CHEMBL1836043)
Show SMILES COc1ccccc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:10:11:18:14.15|
Show InChI InChI=1S/C20H24N2O3/c1-24-19-7-3-2-6-18(19)20(23)21-14-11-15-8-9-16(12-14)22(15)13-17-5-4-10-25-17/h2-7,10,14-16H,8-9,11-13H2,1H3,(H,21,23)/t15-,16-/m1/s1
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 1.00E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354097
PNG
(CHEMBL1836060)
Show SMILES COc1ccc(F)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H27FN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h4,7,9,14-17H,2-3,5-6,8,10-12H2,1H3,(H,22,24)/t15-,16-,17?/m1/s1
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 1.10E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354108
PNG
(CHEMBL1836049)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:14:15:22:18.19|
Show InChI InChI=1S/C22H28N2O5/c1-26-19-9-14(10-20(27-2)21(19)28-3)22(25)23-15-11-16-6-7-17(12-15)24(16)13-18-5-4-8-29-18/h4-5,8-10,15-17H,6-7,11-13H2,1-3H3,(H,23,25)/t16-,17-/m1/s1
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 1.10E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354093
PNG
(CHEMBL1836046)
Show SMILES COc1ccc(OC)c(c1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C21H26N2O4/c1-25-17-7-8-20(26-2)19(12-17)21(24)22-14-10-15-5-6-16(11-14)23(15)13-18-4-3-9-27-18/h3-4,7-9,12,14-16H,5-6,10-11,13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1
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 1.10E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354093
PNG
(CHEMBL1836046)
Show SMILES COc1ccc(OC)c(c1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C21H26N2O4/c1-25-17-7-8-20(26-2)19(12-17)21(24)22-14-10-15-5-6-16(11-14)23(15)13-18-4-3-9-27-18/h3-4,7-9,12,14-16H,5-6,10-11,13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1
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 1.10E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354095
PNG
(CHEMBL1836058)
Show SMILES COc1cccc(c1)C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 |r,TLB:10:11:18:14.15|
Show InChI InChI=1S/C20H28N2O3/c1-24-18-5-2-4-14(10-18)20(23)21-15-11-16-7-8-17(12-15)22(16)13-19-6-3-9-25-19/h2,4-5,10,15-17,19H,3,6-9,11-13H2,1H3,(H,21,23)/t16-,17-,19?/m1/s1
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 1.10E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354100
PNG
(CHEMBL1836105)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1)c1ccc2ccccc2c1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C23H28N2O2/c26-23(18-8-7-16-4-1-2-5-17(16)12-18)24-19-13-20-9-10-21(14-19)25(20)15-22-6-3-11-27-22/h1-2,4-5,7-8,12,19-22H,3,6,9-11,13-15H2,(H,24,26)/t20-,21-,22?/m1/s1
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 1.20E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354092
PNG
(CHEMBL1836045)
Show SMILES COc1ccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccco2)c(OC)c1 |r,TLB:8:9:16:12.13|
Show InChI InChI=1S/C21H26N2O4/c1-25-17-7-8-19(20(12-17)26-2)21(24)22-14-10-15-5-6-16(11-14)23(15)13-18-4-3-9-27-18/h3-4,7-9,12,14-16H,5-6,10-11,13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1
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 1.30E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354103
PNG
(CHEMBL1836108)
Show SMILES COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccccn2)c1OC |r,TLB:9:10:17:13.14|
Show InChI InChI=1S/C22H27N3O3/c1-27-20-8-5-7-19(21(20)28-2)22(26)24-16-12-17-9-10-18(13-16)25(17)14-15-6-3-4-11-23-15/h3-8,11,16-18H,9-10,12-14H2,1-2H3,(H,24,26)/t17-,18-/m1/s1
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 1.40E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354110
PNG
(CHEMBL1836051)
Show SMILES COc1ccc(F)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H23FN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1
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 1.40E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354111
PNG
(CHEMBL1836052)
Show SMILES COc1cc(Cl)ccc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H23ClN2O3/c1-25-19-9-13(21)4-7-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1
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 2.10E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354113
PNG
(CHEMBL1836055)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1)c1cccc2ccccc12 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C23H24N2O2/c26-23(22-9-3-6-16-5-1-2-8-21(16)22)24-17-13-18-10-11-19(14-17)25(18)15-20-7-4-12-27-20/h1-9,12,17-19H,10-11,13-15H2,(H,24,26)/t18-,19-/m1/s1
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 2.30E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354096
PNG
(CHEMBL1836059)
Show SMILES COc1ccc(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H27ClN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h4,7,9,14-17H,2-3,5-6,8,10-12H2,1H3,(H,22,24)/t15-,16-,17?/m1/s1
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 2.40E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354091
PNG
(CHEMBL1836044)
Show SMILES COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccco2)c1OC |r,TLB:9:10:17:13.14|
Show InChI InChI=1S/C21H26N2O4/c1-25-19-7-3-6-18(20(19)26-2)21(24)22-14-11-15-8-9-16(12-14)23(15)13-17-5-4-10-27-17/h3-7,10,14-16H,8-9,11-13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1
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 2.50E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354115
PNG
(CHEMBL1836054)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C20H24ClN3O3/c1-26-19-10-18(22)17(21)9-16(19)20(25)23-12-7-13-4-5-14(8-12)24(13)11-15-3-2-6-27-15/h2-3,6,9-10,12-14H,4-5,7-8,11,22H2,1H3,(H,23,25)/t13-,14-/m1/s1
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 2.50E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354105
PNG
(CHEMBL1836110)
Show SMILES COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccncc2)c1OC |r,TLB:9:10:17:13.14|
Show InChI InChI=1S/C22H27N3O3/c1-27-20-5-3-4-19(21(20)28-2)22(26)24-16-12-17-6-7-18(13-16)25(17)14-15-8-10-23-11-9-15/h3-5,8-11,16-18H,6-7,12-14H2,1-2H3,(H,24,26)/t17-,18-/m1/s1
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 2.50E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354114
PNG
(CHEMBL1836056)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1)c1ccc2ccccc2c1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C23H24N2O2/c26-23(18-8-7-16-4-1-2-5-17(16)12-18)24-19-13-20-9-10-21(14-19)25(20)15-22-6-3-11-27-22/h1-8,11-12,19-21H,9-10,13-15H2,(H,24,26)/t20-,21-/m1/s1
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 2.80E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354108
PNG
(CHEMBL1836049)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:14:15:22:18.19|
Show InChI InChI=1S/C22H28N2O5/c1-26-19-9-14(10-20(27-2)21(19)28-3)22(25)23-15-11-16-6-7-17(12-15)24(16)13-18-5-4-8-29-18/h4-5,8-10,15-17H,6-7,11-13H2,1-3H3,(H,23,25)/t16-,17-/m1/s1
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 2.90E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354101
PNG
(CHEMBL1836106)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccccc1)c1cccc2ccccc12 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C25H26N2O/c28-25(24-12-6-10-19-9-4-5-11-23(19)24)26-20-15-21-13-14-22(16-20)27(21)17-18-7-2-1-3-8-18/h1-12,20-22H,13-17H2,(H,26,28)/t21-,22-/m1/s1
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 2.90E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354091
PNG
(CHEMBL1836044)
Show SMILES COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccco2)c1OC |r,TLB:9:10:17:13.14|
Show InChI InChI=1S/C21H26N2O4/c1-25-19-7-3-6-18(20(19)26-2)21(24)22-14-11-15-8-9-16(12-14)23(15)13-17-5-4-10-27-17/h3-7,10,14-16H,8-9,11-13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1
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 3.00E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354099
PNG
(CHEMBL1836104)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1)c1cccc2ccccc12 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C23H28N2O2/c26-23(22-9-3-6-16-5-1-2-8-21(16)22)24-17-13-18-10-11-19(14-17)25(18)15-20-7-4-12-27-20/h1-3,5-6,8-9,17-20H,4,7,10-15H2,(H,24,26)/t18-,19-,20?/m1/s1
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 3.10E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354094
PNG
(CHEMBL1836057)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1)c1ccccc1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C19H26N2O2/c22-19(14-5-2-1-3-6-14)20-15-11-16-8-9-17(12-15)21(16)13-18-7-4-10-23-18/h1-3,5-6,15-18H,4,7-13H2,(H,20,22)/t16-,17-,18?/m1/s1
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 3.10E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354104
PNG
(CHEMBL1836109)
Show SMILES COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2cccnc2)c1OC |r,TLB:9:10:17:13.14|
Show InChI InChI=1S/C22H27N3O3/c1-27-20-7-3-6-19(21(20)28-2)22(26)24-16-11-17-8-9-18(12-16)25(17)14-15-5-4-10-23-13-15/h3-7,10,13,16-18H,8-9,11-12,14H2,1-2H3,(H,24,26)/t17-,18-/m1/s1
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 3.30E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354100
PNG
(CHEMBL1836105)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1)c1ccc2ccccc2c1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C23H28N2O2/c26-23(18-8-7-16-4-1-2-5-17(16)12-18)24-19-13-20-9-10-21(14-19)25(20)15-22-6-3-11-27-22/h1-2,4-5,7-8,12,19-22H,3,6,9-11,13-15H2,(H,24,26)/t20-,21-,22?/m1/s1
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 3.30E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354099
PNG
(CHEMBL1836104)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1)c1cccc2ccccc12 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C23H28N2O2/c26-23(22-9-3-6-16-5-1-2-8-21(16)22)24-17-13-18-10-11-19(14-17)25(18)15-20-7-4-12-27-20/h1-3,5-6,8-9,17-20H,4,7,10-15H2,(H,24,26)/t18-,19-,20?/m1/s1
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 4.00E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354109
PNG
(CHEMBL1836050)
Show SMILES COc1ccc(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H23ClN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1
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 4.30E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354107
PNG
(CHEMBL1836048 | cid_653771)
Show SMILES COc1cc(OC)cc(c1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C21H26N2O4/c1-25-19-8-14(9-20(12-19)26-2)21(24)22-15-10-16-5-6-17(11-15)23(16)13-18-4-3-7-27-18/h3-4,7-9,12,15-17H,5-6,10-11,13H2,1-2H3,(H,22,24)/t16-,17-/m1/s1
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 4.40E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354096
PNG
(CHEMBL1836059)
Show SMILES COc1ccc(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H27ClN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h4,7,9,14-17H,2-3,5-6,8,10-12H2,1H3,(H,22,24)/t15-,16-,17?/m1/s1
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 4.60E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354098
PNG
(CHEMBL1836061)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C20H28ClN3O3/c1-26-19-10-18(22)17(21)9-16(19)20(25)23-12-7-13-4-5-14(8-12)24(13)11-15-3-2-6-27-15/h9-10,12-15H,2-8,11,22H2,1H3,(H,23,25)/t13-,14-,15?/m1/s1
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 5.70E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354090
PNG
(CHEMBL1836043)
Show SMILES COc1ccccc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:10:11:18:14.15|
Show InChI InChI=1S/C20H24N2O3/c1-24-19-7-3-2-6-18(19)20(23)21-14-11-15-8-9-16(12-14)22(15)13-17-5-4-10-25-17/h2-7,10,14-16H,8-9,11-13H2,1H3,(H,21,23)/t15-,16-/m1/s1
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 6.00E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354090
PNG
(CHEMBL1836043)
Show SMILES COc1ccccc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:10:11:18:14.15|
Show InChI InChI=1S/C20H24N2O3/c1-24-19-7-3-2-6-18(19)20(23)21-14-11-15-8-9-16(12-14)22(15)13-17-5-4-10-25-17/h2-7,10,14-16H,8-9,11-13H2,1H3,(H,21,23)/t15-,16-/m1/s1
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 6.10E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354109
PNG
(CHEMBL1836050)
Show SMILES COc1ccc(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H23ClN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1
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 7.00E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354113
PNG
(CHEMBL1836055)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1)c1cccc2ccccc12 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C23H24N2O2/c26-23(22-9-3-6-16-5-1-2-8-21(16)22)24-17-13-18-10-11-19(14-17)25(18)15-20-7-4-12-27-20/h1-9,12,17-19H,10-11,13-15H2,(H,24,26)/t18-,19-/m1/s1
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 7.10E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354106
PNG
(CHEMBL1836047)
Show SMILES COc1ccc(cc1OC)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C21H26N2O4/c1-25-19-8-5-14(10-20(19)26-2)21(24)22-15-11-16-6-7-17(12-15)23(16)13-18-4-3-9-27-18/h3-5,8-10,15-17H,6-7,11-13H2,1-2H3,(H,22,24)/t16-,17-/m1/s1
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 7.90E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354093
PNG
(CHEMBL1836046)
Show SMILES COc1ccc(OC)c(c1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C21H26N2O4/c1-25-17-7-8-20(26-2)19(12-17)21(24)22-14-10-15-5-6-16(11-14)23(15)13-18-4-3-9-27-18/h3-4,7-9,12,14-16H,5-6,10-11,13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1
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 9.60E+3n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354097
PNG
(CHEMBL1836060)
Show SMILES COc1ccc(F)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H27FN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h4,7,9,14-17H,2-3,5-6,8,10-12H2,1H3,(H,22,24)/t15-,16-,17?/m1/s1
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 1.01E+4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354094
PNG
(CHEMBL1836057)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1)c1ccccc1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C19H26N2O2/c22-19(14-5-2-1-3-6-14)20-15-11-16-8-9-17(12-15)21(16)13-18-7-4-10-23-18/h1-3,5-6,15-18H,4,7-13H2,(H,20,22)/t16-,17-,18?/m1/s1
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 1.02E+4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354095
PNG
(CHEMBL1836058)
Show SMILES COc1cccc(c1)C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 |r,TLB:10:11:18:14.15|
Show InChI InChI=1S/C20H28N2O3/c1-24-18-5-2-4-14(10-18)20(23)21-15-11-16-7-8-17(12-15)22(16)13-19-6-3-9-25-19/h2,4-5,10,15-17,19H,3,6-9,11-13H2,1H3,(H,21,23)/t16-,17-,19?/m1/s1
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 1.03E+4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354097
PNG
(CHEMBL1836060)
Show SMILES COc1ccc(F)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H27FN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h4,7,9,14-17H,2-3,5-6,8,10-12H2,1H3,(H,22,24)/t15-,16-,17?/m1/s1
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 1.24E+4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354107
PNG
(CHEMBL1836048 | cid_653771)
Show SMILES COc1cc(OC)cc(c1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C21H26N2O4/c1-25-19-8-14(9-20(12-19)26-2)21(24)22-15-10-16-5-6-17(11-15)23(16)13-18-4-3-7-27-18/h3-4,7-9,12,15-17H,5-6,10-11,13H2,1-2H3,(H,22,24)/t16-,17-/m1/s1
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 1.32E+4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354112
PNG
(CHEMBL1836053)
Show SMILES [O-][N+](=O)c1cc(Cl)ccc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C19H20ClN3O4/c20-12-3-6-17(18(8-12)23(25)26)19(24)21-13-9-14-4-5-15(10-13)22(14)11-16-2-1-7-27-16/h1-3,6-8,13-15H,4-5,9-11H2,(H,21,24)/t14-,15-/m1/s1
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 1.60E+4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354110
PNG
(CHEMBL1836051)
Show SMILES COc1ccc(F)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H23FN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1
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 1.72E+4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354112
PNG
(CHEMBL1836053)
Show SMILES [O-][N+](=O)c1cc(Cl)ccc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C19H20ClN3O4/c20-12-3-6-17(18(8-12)23(25)26)19(24)21-13-9-14-4-5-15(10-13)22(14)11-16-2-1-7-27-16/h1-3,6-8,13-15H,4-5,9-11H2,(H,21,24)/t14-,15-/m1/s1
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 1.90E+4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354092
PNG
(CHEMBL1836045)
Show SMILES COc1ccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccco2)c(OC)c1 |r,TLB:8:9:16:12.13|
Show InChI InChI=1S/C21H26N2O4/c1-25-17-7-8-19(20(12-17)26-2)21(24)22-14-10-15-5-6-16(11-14)23(15)13-18-4-3-9-27-18/h3-4,7-9,12,14-16H,5-6,10-11,13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1
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 1.90E+4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50354112
PNG
(CHEMBL1836053)
Show SMILES [O-][N+](=O)c1cc(Cl)ccc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C19H20ClN3O4/c20-12-3-6-17(18(8-12)23(25)26)19(24)21-13-9-14-4-5-15(10-13)22(14)11-16-2-1-7-27-16/h1-3,6-8,13-15H,4-5,9-11H2,(H,21,24)/t14-,15-/m1/s1
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 3.20E+4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortex after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354109
PNG
(CHEMBL1836050)
Show SMILES COc1ccc(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H23ClN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1
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 4.40E+4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354108
PNG
(CHEMBL1836049)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:14:15:22:18.19|
Show InChI InChI=1S/C22H28N2O5/c1-26-19-9-14(10-20(27-2)21(19)28-3)22(25)23-15-11-16-6-7-17(12-15)24(16)13-18-5-4-8-29-18/h4-5,8-10,15-17H,6-7,11-13H2,1-3H3,(H,23,25)/t16-,17-/m1/s1
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 5.22E+4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354106
PNG
(CHEMBL1836047)
Show SMILES COc1ccc(cc1OC)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C21H26N2O4/c1-25-19-8-5-14(10-20(19)26-2)21(24)22-15-11-16-6-7-17(12-15)23(16)13-18-4-3-9-27-18/h3-5,8-10,15-17H,6-7,11-13H2,1-2H3,(H,22,24)/t16-,17-/m1/s1
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 5.73E+4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354113
PNG
(CHEMBL1836055)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1)c1cccc2ccccc12 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C23H24N2O2/c26-23(22-9-3-6-16-5-1-2-8-21(16)22)24-17-13-18-10-11-19(14-17)25(18)15-20-7-4-12-27-20/h1-9,12,17-19H,10-11,13-15H2,(H,24,26)/t18-,19-/m1/s1
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 6.67E+4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354106
PNG
(CHEMBL1836047)
Show SMILES COc1ccc(cc1OC)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:12:13:20:16.17|
Show InChI InChI=1S/C21H26N2O4/c1-25-19-8-5-14(10-20(19)26-2)21(24)22-15-11-16-6-7-17(12-15)23(16)13-18-4-3-9-27-18/h3-5,8-10,15-17H,6-7,11-13H2,1-2H3,(H,22,24)/t16-,17-/m1/s1
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 6.88E+4n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354091
PNG
(CHEMBL1836044)
Show SMILES COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccco2)c1OC |r,TLB:9:10:17:13.14|
Show InChI InChI=1S/C21H26N2O4/c1-25-19-7-3-6-18(20(19)26-2)21(24)22-14-11-15-8-9-16(12-14)23(15)13-17-5-4-10-27-17/h3-7,10,14-16H,8-9,11-13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354095
PNG
(CHEMBL1836058)
Show SMILES COc1cccc(c1)C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 |r,TLB:10:11:18:14.15|
Show InChI InChI=1S/C20H28N2O3/c1-24-18-5-2-4-14(10-18)20(23)21-15-11-16-7-8-17(12-15)22(16)13-19-6-3-9-25-19/h2,4-5,10,15-17,19H,3,6-9,11-13H2,1H3,(H,21,23)/t16-,17-,19?/m1/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354091
PNG
(CHEMBL1836044)
Show SMILES COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccco2)c1OC |r,TLB:9:10:17:13.14|
Show InChI InChI=1S/C21H26N2O4/c1-25-19-7-3-6-18(20(19)26-2)21(24)22-14-11-15-8-9-16(12-14)23(15)13-17-5-4-10-27-17/h3-7,10,14-16H,8-9,11-13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50354094
PNG
(CHEMBL1836057)
Show SMILES O=C(NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1)c1ccccc1 |r,TLB:2:3:10:6.7|
Show InChI InChI=1S/C19H26N2O2/c22-19(14-5-2-1-3-6-14)20-15-11-16-8-9-17(12-15)21(16)13-18-7-4-10-23-18/h1-3,5-6,15-18H,4,7-13H2,(H,20,22)/t16-,17-,18?/m1/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50354109
PNG
(CHEMBL1836050)
Show SMILES COc1ccc(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:11:12:19:15.16|
Show InChI InChI=1S/C20H23ClN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1
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UniProtKB/SwissProt

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UniChem

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PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



Medical University of Warsaw

Curated by ChEMBL


Assay Description
Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortex after 15 mins by scintillation counting

Eur J Med Chem 46: 4474-88 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.022
BindingDB Entry DOI: 10.7270/Q2Z0395D
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%