Affinity Data by PubMed id=21820898

PubMed code 21820898

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50351152 (CHEMBL1817917) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Inhibition of CCL5 binding to CCR5 expressed in CHO cells				Bioorg Med Chem Lett 21: 5159-63 (2011) Article DOI: 10.1016/j.bmcl.2011.07.058 BindingDB Entry DOI: 10.7270/Q2MP53NR
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50351152 (CHEMBL1817917) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at human CCR5 receptor expressed in MOLT4/CCR5 cells assessed as inhibition of CCL5-induced intracellular calcium mobilization by...				Bioorg Med Chem Lett 21: 5159-63 (2011) Article DOI: 10.1016/j.bmcl.2011.07.058 BindingDB Entry DOI: 10.7270/Q2MP53NR
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50242053 (6,8-didec-(1Z)-enyl-5,7-dimethyl-2,3-dihydro-1H-in...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of [125I]-gp120 from human CCR5				Bioorg Med Chem Lett 21: 5159-63 (2011) Article DOI: 10.1016/j.bmcl.2011.07.058 BindingDB Entry DOI: 10.7270/Q2MP53NR
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50351147 (CHEMBL1817912 \| CHEMBL2057816) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at human CCR5 receptor expressed in MOLT4/CCR5 cells assessed as inhibition of CCL5-induced intracellular calcium mobilization by...				Bioorg Med Chem Lett 21: 5159-63 (2011) Article DOI: 10.1016/j.bmcl.2011.07.058 BindingDB Entry DOI: 10.7270/Q2MP53NR
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50242053 (6,8-didec-(1Z)-enyl-5,7-dimethyl-2,3-dihydro-1H-in...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at human CCR5 receptor expressed in MOLT4/CCR5 cells assessed as inhibition of CCL5-induced intracellular calcium mobilization by...				Bioorg Med Chem Lett 21: 5159-63 (2011) Article DOI: 10.1016/j.bmcl.2011.07.058 BindingDB Entry DOI: 10.7270/Q2MP53NR
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50351144 (CHEMBL1817909 \| CHEMBL2057810) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at human CCR5 receptor expressed in MOLT4/CCR5 cells assessed as inhibition of CCL5-induced intracellular calcium mobilization by...				Bioorg Med Chem Lett 21: 5159-63 (2011) Article DOI: 10.1016/j.bmcl.2011.07.058 BindingDB Entry DOI: 10.7270/Q2MP53NR
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50351145 (CHEMBL1817910 \| CHEMBL2057811) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at human CCR5 receptor expressed in MOLT4/CCR5 cells assessed as inhibition of CCL5-induced intracellular calcium mobilization by...				Bioorg Med Chem Lett 21: 5159-63 (2011) Article DOI: 10.1016/j.bmcl.2011.07.058 BindingDB Entry DOI: 10.7270/Q2MP53NR
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50351149 (CHEMBL1817914 \| CHEMBL2057815) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at human CCR5 receptor expressed in MOLT4/CCR5 cells assessed as inhibition of CCL5-induced intracellular calcium mobilization by...				Bioorg Med Chem Lett 21: 5159-63 (2011) Article DOI: 10.1016/j.bmcl.2011.07.058 BindingDB Entry DOI: 10.7270/Q2MP53NR
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50351146 (CHEMBL1817911 \| CHEMBL2057814) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at human CCR5 receptor expressed in MOLT4/CCR5 cells assessed as inhibition of CCL5-induced intracellular calcium mobilization by...				Bioorg Med Chem Lett 21: 5159-63 (2011) Article DOI: 10.1016/j.bmcl.2011.07.058 BindingDB Entry DOI: 10.7270/Q2MP53NR
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50351148 (CHEMBL1817913 \| CHEMBL2057818) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at human CCR5 receptor expressed in MOLT4/CCR5 cells assessed as inhibition of CCL5-induced intracellular calcium mobilization by...				Bioorg Med Chem Lett 21: 5159-63 (2011) Article DOI: 10.1016/j.bmcl.2011.07.058 BindingDB Entry DOI: 10.7270/Q2MP53NR
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50351151 (CHEMBL1817916 \| CHEMBL2057819) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at human CCR5 receptor expressed in MOLT4/CCR5 cells assessed as inhibition of CCL5-induced intracellular calcium mobilization by...				Bioorg Med Chem Lett 21: 5159-63 (2011) Article DOI: 10.1016/j.bmcl.2011.07.058 BindingDB Entry DOI: 10.7270/Q2MP53NR
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50351150 (CHEMBL1817915 \| CHEMBL2057817) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at human CCR5 receptor expressed in MOLT4/CCR5 cells assessed as inhibition of CCL5-induced intracellular calcium mobilization by...				Bioorg Med Chem Lett 21: 5159-63 (2011) Article DOI: 10.1016/j.bmcl.2011.07.058 BindingDB Entry DOI: 10.7270/Q2MP53NR
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%