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PubMed code 21843935

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))
BDBM50354140
PNG
(CHEMBL570406)
Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#8]-c1ccc(\[#6]=[#6]\[#6](-[#8])=O)cc1
Show InChI InChI=1S/C14H16O3/c1-11(2)9-10-17-13-6-3-12(4-7-13)5-8-14(15)16/h3-9H,10H2,1-2H3,(H,15,16)/b8-5+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.51E+4n/an/an/an/an/an/a



Universit£ 'G. D'Annunzio' di Chieti-Pescara

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 using TMPD as substrate preincubated for 15 mins


Bioorg Med Chem Lett 21: 5995-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.040
BindingDB Entry DOI: 10.7270/Q23X8717
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))
BDBM50354139
PNG
(CHEMBL221960)
Show SMILES [#6]-[#8]-c1cc(\[#6]=[#6]\[#6](-[#8])=O)ccc1-[#8]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6]
Show InChI InChI=1S/C20H26O4/c1-15(2)6-5-7-16(3)12-13-24-18-10-8-17(9-11-20(21)22)14-19(18)23-4/h6,8-12,14H,5,7,13H2,1-4H3,(H,21,22)/b11-9+,16-12+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.42E+4n/an/an/an/an/an/a



Universit£ 'G. D'Annunzio' di Chieti-Pescara

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 using TMPD as substrate preincubated for 15 mins


Bioorg Med Chem Lett 21: 5995-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.040
BindingDB Entry DOI: 10.7270/Q23X8717
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%