Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM236549 (4-(9-(2,4-dimethoxyphenyl)-1,8-dioxo-1,2,3,4,5,6,7...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM236550 (4-(9-(4-methoxyphenyl)-1,8-dioxo-1,2,3,4,5,6,7,8-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM236550 (4-(9-(4-methoxyphenyl)-1,8-dioxo-1,2,3,4,5,6,7,8-o...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM236549 (4-(9-(2,4-dimethoxyphenyl)-1,8-dioxo-1,2,3,4,5,6,7...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM236554 (4-(9-(2,4-Dichlorophenyl)-2,2,7,7-tetramethyl¿1,8-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM236552 (4-(9-(4-Hydroxyphenyl)-2,2,7,7-tetramethyl¿1,8-dio...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM236548 (4-(3,3,6,6-tetramethyl-1,8-dioxo-9-(pyridin-2-yl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM236547 (4-(9-(4-Methoxyphenyl)-3,3,6,6-tetramethyl-1,8-dio...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM236551 (4-(9-(4-Cyanophenyl)-2,2,7,7-tetramethyl¿1,8-dioxo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM236553 (4-(9-(3,4-Dimethoxyphenyl)-2,2,7,7-tetramethyl¿1,8...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM236552 (4-(9-(4-Hydroxyphenyl)-2,2,7,7-tetramethyl¿1,8-dio...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 125 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM236548 (4-(3,3,6,6-tetramethyl-1,8-dioxo-9-(pyridin-2-yl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM236551 (4-(9-(4-Cyanophenyl)-2,2,7,7-tetramethyl¿1,8-dioxo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 135 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM236547 (4-(9-(4-Methoxyphenyl)-3,3,6,6-tetramethyl-1,8-dio...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM236553 (4-(9-(3,4-Dimethoxyphenyl)-2,2,7,7-tetramethyl¿1,8...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 205 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM236554 (4-(9-(2,4-Dichlorophenyl)-2,2,7,7-tetramethyl¿1,8-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM236546 (4-(9-(4-Cyanophenyl)-3,3,6,6-tetramethyl-1,8-dioxo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM236546 (4-(9-(4-Cyanophenyl)-3,3,6,6-tetramethyl-1,8-dioxo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | 2.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 3.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM10857 (4-aminobenzene-1-sulfonamide | CHEMBL21 | Sulfanil...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM10857 (4-aminobenzene-1-sulfonamide | CHEMBL21 | Sulfanil...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description Esterase activities of hCA I and hCA II isoenzymes, eluted from affinity column,were determined by hydrolysis of p-nitrophenylacetate. The change of ... | J Enzyme Inhib Med Chem 27: 509-14 (2012) Article DOI: 10.3109/14756366.2011.599029 BindingDB Entry DOI: 10.7270/Q27W6B3H | |||||||||||
More data for this Ligand-Target Pair |