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PubMed code 21885167

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50353747
PNG
(CHEMBL561013 | JWH-018)
Show SMILES CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc12
Show InChI InChI=1S/C24H23NO/c1-2-3-8-16-25-17-22(20-13-6-7-15-23(20)25)24(26)21-14-9-11-18-10-4-5-12-19(18)21/h4-7,9-15,17H,2-3,8,16H2,1H3
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Article
PubMed
n/an/a 280n/an/an/an/an/an/a



Abbott Healthcare Products B.V.

Curated by ChEMBL


Assay Description
Activation of CB1 receptor in Wistar rat prelimbic prefrontal cortex assessed as reduction of field excitatory postsynaptic potential amplitude after...


Eur J Med Chem 46: 5086-98 (2011)


Article DOI: 10.1016/j.ejmech.2011.08.021
BindingDB Entry DOI: 10.7270/Q26W9BFT
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50353746
PNG
(CHEMBL1828805)
Show SMILES CCCCCn1cc(C(=O)Nc2cccc3ccccc23)c2ccccc12
Show InChI InChI=1S/C24H24N2O/c1-2-3-8-16-26-17-21(20-13-6-7-15-23(20)26)24(27)25-22-14-9-11-18-10-4-5-12-19(18)22/h4-7,9-15,17H,2-3,8,16H2,1H3,(H,25,27)
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Article
PubMed
n/an/a 450n/an/an/an/an/an/a



Abbott Healthcare Products B.V.

Curated by ChEMBL


Assay Description
Activation of CB1 receptor in Wistar rat prelimbic prefrontal cortex assessed as reduction of field excitatory postsynaptic potential amplitude after...


Eur J Med Chem 46: 5086-98 (2011)


Article DOI: 10.1016/j.ejmech.2011.08.021
BindingDB Entry DOI: 10.7270/Q26W9BFT
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50353748
PNG
(CHEMBL1828809)
Show SMILES CCCCCn1cc(C(=O)c2cccc3ccccc23)c2cccnc12
Show InChI InChI=1S/C23H22N2O/c1-2-3-6-15-25-16-21(20-13-8-14-24-23(20)25)22(26)19-12-7-10-17-9-4-5-11-18(17)19/h4-5,7-14,16H,2-3,6,15H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 520n/an/an/an/an/an/a



Abbott Healthcare Products B.V.

Curated by ChEMBL


Assay Description
Activation of CB1 receptor in Wistar rat prelimbic prefrontal cortex assessed as reduction of field excitatory postsynaptic potential amplitude after...


Eur J Med Chem 46: 5086-98 (2011)


Article DOI: 10.1016/j.ejmech.2011.08.021
BindingDB Entry DOI: 10.7270/Q26W9BFT
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%