Found 28 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358288
(CHEMBL1922404)Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C19H15N7O/c1-25-11-13(10-21-25)16-5-6-17-22-23-18(26(17)24-16)9-12-3-2-4-15-14(12)7-8-20-19(15)27/h2-8,10-11H,9H2,1H3,(H,20,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358291
(CHEMBL1922406)Show SMILES OCCn1cc(cn1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C20H17N7O2/c28-9-8-26-12-14(11-22-26)17-4-5-18-23-24-19(27(18)25-17)10-13-2-1-3-16-15(13)6-7-21-20(16)29/h1-7,11-12,28H,8-10H2,(H,21,29) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358301
(CHEMBL1922416)Show SMILES Fc1cccc(c1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C21H14FN5O/c22-15-5-1-4-14(11-15)18-7-8-19-24-25-20(27(19)26-18)12-13-3-2-6-17-16(13)9-10-23-21(17)28/h1-11H,12H2,(H,23,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358289
(CHEMBL1922405)Show SMILES O=c1[nH]ccc2c(Cc3nnc4ccc(nn34)-c3ccccc3)cccc12 Show InChI InChI=1S/C21H15N5O/c27-21-17-8-4-7-15(16(17)11-12-22-21)13-20-24-23-19-10-9-18(25-26(19)20)14-5-2-1-3-6-14/h1-12H,13H2,(H,22,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358304
(CHEMBL1922419)Show SMILES Oc1cccc(c1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C21H15N5O2/c27-15-5-1-4-14(11-15)18-7-8-19-23-24-20(26(19)25-18)12-13-3-2-6-17-16(13)9-10-22-21(17)28/h1-11,27H,12H2,(H,22,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358303
(CHEMBL1922418)Show SMILES O=c1[nH]ccc2c(Cc3nnc4ccc(nn34)-c3cccc(c3)C#N)cccc12 Show InChI InChI=1S/C22H14N6O/c23-13-14-3-1-5-16(11-14)19-7-8-20-25-26-21(28(20)27-19)12-15-4-2-6-18-17(15)9-10-24-22(18)29/h1-11H,12H2,(H,24,29) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358299
(CHEMBL1922414)Show SMILES Clc1ccccc1-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C21H14ClN5O/c22-17-7-2-1-5-16(17)18-8-9-19-24-25-20(27(19)26-18)12-13-4-3-6-15-14(13)10-11-23-21(15)28/h1-11H,12H2,(H,23,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358295
(CHEMBL1922410)Show SMILES O=c1[nH]ccc2c(Cc3nnc4ccc(nn34)-c3ccsc3)cccc12 Show InChI InChI=1S/C19H13N5OS/c25-19-15-3-1-2-12(14(15)6-8-20-19)10-18-22-21-17-5-4-16(23-24(17)18)13-7-9-26-11-13/h1-9,11H,10H2,(H,20,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358302
(CHEMBL1922417)Show SMILES [O-][N+](=O)c1cccc(c1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C21H14N6O3/c28-21-17-6-2-3-13(16(17)9-10-22-21)12-20-24-23-19-8-7-18(25-26(19)20)14-4-1-5-15(11-14)27(29)30/h1-11H,12H2,(H,22,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358305
(CHEMBL1922420)Show SMILES COc1cccc(c1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C22H17N5O2/c1-29-16-6-2-5-15(12-16)19-8-9-20-24-25-21(27(20)26-19)13-14-4-3-7-18-17(14)10-11-23-22(18)28/h2-12H,13H2,1H3,(H,23,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358296
(CHEMBL1922411)Show SMILES O=c1[nH]ccc2c(Cc3nnc4ccc(nn34)-c3cccnc3)cccc12 Show InChI InChI=1S/C20H14N6O/c27-20-16-5-1-3-13(15(16)8-10-22-20)11-19-24-23-18-7-6-17(25-26(18)19)14-4-2-9-21-12-14/h1-10,12H,11H2,(H,22,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358290
(CHEMBL1921807)Show SMILES O=c1[nH]ccc2c(Cc3nnc4ccc(nn34)-c3cn[nH]c3)cccc12 Show InChI InChI=1S/C18H13N7O/c26-18-14-3-1-2-11(13(14)6-7-19-18)8-17-23-22-16-5-4-15(24-25(16)17)12-9-20-21-10-12/h1-7,9-10H,8H2,(H,19,26)(H,20,21) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358300
(CHEMBL1922415)Show SMILES Clc1cccc(c1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C21H14ClN5O/c22-15-5-1-4-14(11-15)18-7-8-19-24-25-20(27(19)26-18)12-13-3-2-6-17-16(13)9-10-23-21(17)28/h1-11H,12H2,(H,23,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358297
(CHEMBL1922412)Show SMILES O=c1[nH]ccc2c(Cc3nnc4ccc(nn34)-c3csc4ccccc34)cccc12 Show InChI InChI=1S/C23H15N5OS/c29-23-17-6-3-4-14(15(17)10-11-24-23)12-22-26-25-21-9-8-19(27-28(21)22)18-13-30-20-7-2-1-5-16(18)20/h1-11,13H,12H2,(H,24,29) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358293
(CHEMBL1922408)Show SMILES O=c1[nH]ccc2c(Cc3nnc4ccc(nn34)N3CCCC3)cccc12 Show InChI InChI=1S/C19H18N6O/c26-19-15-5-3-4-13(14(15)8-9-20-19)12-18-22-21-16-6-7-17(23-25(16)18)24-10-1-2-11-24/h3-9H,1-2,10-12H2,(H,20,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358292
(CHEMBL1922407)Show SMILES O=c1[nH]ccc2c(Cc3nnc4ccc(nn34)-c3cnn(c3)C3CCNCC3)cccc12 Show InChI InChI=1S/C23H22N8O/c32-23-19-3-1-2-15(18(19)8-11-25-23)12-22-28-27-21-5-4-20(29-31(21)22)16-13-26-30(14-16)17-6-9-24-10-7-17/h1-5,8,11,13-14,17,24H,6-7,9-10,12H2,(H,25,32) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358294
(CHEMBL1922409)Show SMILES O=c1[nH]ccc2c(Cc3nnc4ccc(nn34)N3CCCCC3)cccc12 Show InChI InChI=1S/C20H20N6O/c27-20-16-6-4-5-14(15(16)9-10-21-20)13-19-23-22-17-7-8-18(24-26(17)19)25-11-2-1-3-12-25/h4-10H,1-3,11-13H2,(H,21,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358307
(CHEMBL1922422)Show SMILES CCn1ccc2c(Cc3nnc4ccc(nn34)-c3cccc(F)c3)cccc2c1=O Show InChI InChI=1S/C23H18FN5O/c1-2-28-12-11-18-15(5-4-8-19(18)23(28)30)14-22-26-25-21-10-9-20(27-29(21)22)16-6-3-7-17(24)13-16/h3-13H,2,14H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358298
(CHEMBL1922413)Show SMILES Cc1ccccc1-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C22H17N5O/c1-14-5-2-3-7-16(14)19-9-10-20-24-25-21(27(20)26-19)13-15-6-4-8-18-17(15)11-12-23-22(18)28/h2-12H,13H2,1H3,(H,23,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50358306
(CHEMBL1922421)Show SMILES Cn1ccc2c(Cc3nnc4ccc(nn34)-c3cccc(F)c3)cccc2c1=O Show InChI InChI=1S/C22H16FN5O/c1-27-11-10-17-14(4-3-7-18(17)22(27)29)13-21-25-24-20-9-8-19(26-28(20)21)15-5-2-6-16(23)12-15/h2-12H,13H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-met by HTRF assay |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50358289
(CHEMBL1922405)Show SMILES O=c1[nH]ccc2c(Cc3nnc4ccc(nn34)-c3ccccc3)cccc12 Show InChI InChI=1S/C21H15N5O/c27-21-17-8-4-7-15(16(17)11-12-22-21)13-20-24-23-19-10-9-18(25-26(19)20)14-5-2-1-3-6-14/h1-12H,13H2,(H,22,27) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM50358288
(CHEMBL1922404)Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C19H15N7O/c1-25-11-13(10-21-25)16-5-6-17-22-23-18(26(17)24-16)9-12-3-2-4-15-14(12)7-8-20-19(15)27/h2-8,10-11H,9H2,1H3,(H,20,27) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of TRKA |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Macrophage-stimulating protein receptor
(Homo sapiens (Human)) | BDBM50358289
(CHEMBL1922405)Show SMILES O=c1[nH]ccc2c(Cc3nnc4ccc(nn34)-c3ccccc3)cccc12 Show InChI InChI=1S/C21H15N5O/c27-21-17-8-4-7-15(16(17)11-12-22-21)13-20-24-23-19-10-9-18(25-26(19)20)14-5-2-1-3-6-14/h1-12H,13H2,(H,22,27) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of RON |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50358289
(CHEMBL1922405)Show SMILES O=c1[nH]ccc2c(Cc3nnc4ccc(nn34)-c3ccccc3)cccc12 Show InChI InChI=1S/C21H15N5O/c27-21-17-8-4-7-15(16(17)11-12-22-21)13-20-24-23-19-10-9-18(25-26(19)20)14-5-2-1-3-6-14/h1-12H,13H2,(H,22,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of AurA |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Macrophage-stimulating protein receptor
(Homo sapiens (Human)) | BDBM50358288
(CHEMBL1922404)Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C19H15N7O/c1-25-11-13(10-21-25)16-5-6-17-22-23-18(26(17)24-16)9-12-3-2-4-15-14(12)7-8-20-19(15)27/h2-8,10-11H,9H2,1H3,(H,20,27) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of RON |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM50358289
(CHEMBL1922405)Show SMILES O=c1[nH]ccc2c(Cc3nnc4ccc(nn34)-c3ccccc3)cccc12 Show InChI InChI=1S/C21H15N5O/c27-21-17-8-4-7-15(16(17)11-12-22-21)13-20-24-23-19-10-9-18(25-26(19)20)14-5-2-1-3-6-14/h1-12H,13H2,(H,22,27) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of TRKA |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50358288
(CHEMBL1922404)Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C19H15N7O/c1-25-11-13(10-21-25)16-5-6-17-22-23-18(26(17)24-16)9-12-3-2-4-15-14(12)7-8-20-19(15)27/h2-8,10-11H,9H2,1H3,(H,20,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of AurA |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50358288
(CHEMBL1922404)Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C19H15N7O/c1-25-11-13(10-21-25)16-5-6-17-22-23-18(26(17)24-16)9-12-3-2-4-15-14(12)7-8-20-19(15)27/h2-8,10-11H,9H2,1H3,(H,20,27) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 |
Bioorg Med Chem Lett 21: 7185-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.066
BindingDB Entry DOI: 10.7270/Q24Q7VDG |
More data for this
Ligand-Target Pair | |
Search and Browse
