Affinity Data by PubMed id=22030030

PubMed code 22030030

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50358828 (CHEMBL1922946) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville campus) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D2 overexpressed in Escherichia coli after 15 mins using [3H]cAMP by scintillation proximity assay				Bioorg Med Chem Lett 21: 7089-93 (2011) Article DOI: 10.1016/j.bmcl.2011.09.109 BindingDB Entry DOI: 10.7270/Q2D21Z1F
Monash University (Parkville campus) Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50358830 (CHEMBL1923066) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville campus) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D2 overexpressed in Escherichia coli after 15 mins using [3H]cAMP by scintillation proximity assay				Bioorg Med Chem Lett 21: 7089-93 (2011) Article DOI: 10.1016/j.bmcl.2011.09.109 BindingDB Entry DOI: 10.7270/Q2D21Z1F
Monash University (Parkville campus) Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50084018 (2-Phenylacetylamino-4,7-dihydro-5H-thieno[2,3-c]py...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville campus) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D2 overexpressed in Escherichia coli after 15 mins using [3H]cAMP by scintillation proximity assay				Bioorg Med Chem Lett 21: 7089-93 (2011) Article DOI: 10.1016/j.bmcl.2011.09.109 BindingDB Entry DOI: 10.7270/Q2D21Z1F
Monash University (Parkville campus) Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50358829 (CHEMBL1923060) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville campus) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D2 overexpressed in Escherichia coli after 15 mins using [3H]cAMP by scintillation proximity assay				Bioorg Med Chem Lett 21: 7089-93 (2011) Article DOI: 10.1016/j.bmcl.2011.09.109 BindingDB Entry DOI: 10.7270/Q2D21Z1F
Monash University (Parkville campus) Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50358827 (CHEMBL1922942) Show SMILES CCOC(=O)c1c(NC(=O)Cc2ccccc2)sc2CCCCc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville campus) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D2 overexpressed in Escherichia coli after 15 mins using [3H]cAMP by scintillation proximity assay				Bioorg Med Chem Lett 21: 7089-93 (2011) Article DOI: 10.1016/j.bmcl.2011.09.109 BindingDB Entry DOI: 10.7270/Q2D21Z1F
Monash University (Parkville campus) Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%