Found 44 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50358924
(CHEMBL1923681)Show SMILES COc1ccc2C(N(CCc2c1)S(N)(=O)=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C16H17N3O5S/c1-24-14-6-7-15-12(10-14)8-9-18(25(17,22)23)16(15)11-2-4-13(5-3-11)19(20)21/h2-7,10,16H,8-9H2,1H3,(H2,17,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human CA9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM10888
(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)Show InChI InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
Article
PubMed
| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human CA9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM50358923
(CHEMBL1923680)Show SMILES COc1ccc2C(N(CCc2c1)S(N)(=O)=O)c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C16H17N3O5S/c1-24-14-5-6-15-11(10-14)7-8-18(25(17,22)23)16(15)12-3-2-4-13(9-12)19(20)21/h2-6,9-10,16H,7-8H2,1H3,(H2,17,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM50358921
(CHEMBL1923678)Show InChI InChI=1S/C16H17FN2O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9H2,1H3,(H2,18,20,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50358920
(CHEMBL1923677)Show SMILES COc1ccc2C(N(CCc2c1)S(N)(=O)=O)c1ccc(cc1)C#N Show InChI InChI=1S/C17H17N3O3S/c1-23-15-6-7-16-14(10-15)8-9-20(24(19,21)22)17(16)13-4-2-12(11-18)3-5-13/h2-7,10,17H,8-9H2,1H3,(H2,19,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human CA9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM50358925
(CHEMBL1923682)Show InChI InChI=1S/C16H19N3O3S/c1-22-14-5-6-15-11(10-14)7-8-19(23(18,20)21)16(15)12-3-2-4-13(17)9-12/h2-6,9-10,16H,7-8,17H2,1H3,(H2,18,20,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50358922
(CHEMBL1923679)Show InChI InChI=1S/C17H20N2O3S/c1-12-3-5-13(6-4-12)17-16-8-7-15(22-2)11-14(16)9-10-19(17)23(18,20)21/h3-8,11,17H,9-10H2,1-2H3,(H2,18,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human CA9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM50358922
(CHEMBL1923679)Show InChI InChI=1S/C17H20N2O3S/c1-12-3-5-13(6-4-12)17-16-8-7-15(22-2)11-14(16)9-10-19(17)23(18,20)21/h3-8,11,17H,9-10H2,1-2H3,(H2,18,20,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM50358917
(CHEMBL1923674)Show InChI InChI=1S/C16H18N2O3S/c1-21-14-7-8-15-13(11-14)9-10-18(22(17,19)20)16(15)12-5-3-2-4-6-12/h2-8,11,16H,9-10H2,1H3,(H2,17,19,20) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM50358918
(CHEMBL1923675)Show InChI InChI=1S/C16H17BrN2O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9H2,1H3,(H2,18,20,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM50358926
(CHEMBL1923683)Show InChI InChI=1S/C16H19N3O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9,17H2,1H3,(H2,18,20,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM50358924
(CHEMBL1923681)Show SMILES COc1ccc2C(N(CCc2c1)S(N)(=O)=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C16H17N3O5S/c1-24-14-6-7-15-12(10-14)8-9-18(25(17,22)23)16(15)11-2-4-13(5-3-11)19(20)21/h2-7,10,16H,8-9H2,1H3,(H2,17,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50358926
(CHEMBL1923683)Show InChI InChI=1S/C16H19N3O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9,17H2,1H3,(H2,18,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human CA9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50358923
(CHEMBL1923680)Show SMILES COc1ccc2C(N(CCc2c1)S(N)(=O)=O)c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C16H17N3O5S/c1-24-14-5-6-15-11(10-14)7-8-18(25(17,22)23)16(15)12-3-2-4-13(9-12)19(20)21/h2-6,9-10,16H,7-8H2,1H3,(H2,17,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human CA9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50358925
(CHEMBL1923682)Show InChI InChI=1S/C16H19N3O3S/c1-22-14-5-6-15-11(10-14)7-8-19(23(18,20)21)16(15)12-3-2-4-13(17)9-12/h2-6,9-10,16H,7-8,17H2,1H3,(H2,18,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human CA9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM50358920
(CHEMBL1923677)Show SMILES COc1ccc2C(N(CCc2c1)S(N)(=O)=O)c1ccc(cc1)C#N Show InChI InChI=1S/C17H17N3O3S/c1-23-15-6-7-16-14(10-15)8-9-20(24(19,21)22)17(16)13-4-2-12(11-18)3-5-13/h2-7,10,17H,8-9H2,1H3,(H2,19,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 19.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50358919
(CHEMBL1923676)Show InChI InChI=1S/C16H17ClN2O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9H2,1H3,(H2,18,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 21.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human CA9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50358921
(CHEMBL1923678)Show InChI InChI=1S/C16H17FN2O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9H2,1H3,(H2,18,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human CA9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10888
(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)Show InChI InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
Article
PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA2 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM50358919
(CHEMBL1923676)Show InChI InChI=1S/C16H17ClN2O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9H2,1H3,(H2,18,20,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 53.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM10888
(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)Show InChI InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
Article
PubMed
| 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA1 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50358918
(CHEMBL1923675)Show InChI InChI=1S/C16H17BrN2O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9H2,1H3,(H2,18,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 60.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human CA9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50358917
(CHEMBL1923674)Show InChI InChI=1S/C16H18N2O3S/c1-21-14-7-8-15-13(11-14)9-10-18(22(17,19)20)16(15)12-5-3-2-4-6-12/h2-8,11,16H,9-10H2,1H3,(H2,17,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 78 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human CA9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50358922
(CHEMBL1923679)Show InChI InChI=1S/C17H20N2O3S/c1-12-3-5-13(6-4-12)17-16-8-7-15(22-2)11-14(16)9-10-19(17)23(18,20)21/h3-8,11,17H,9-10H2,1-2H3,(H2,18,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 88 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA2 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50358920
(CHEMBL1923677)Show SMILES COc1ccc2C(N(CCc2c1)S(N)(=O)=O)c1ccc(cc1)C#N Show InChI InChI=1S/C17H17N3O3S/c1-23-15-6-7-16-14(10-15)8-9-20(24(19,21)22)17(16)13-4-2-12(11-18)3-5-13/h2-7,10,17H,8-9H2,1H3,(H2,19,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 91 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA2 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50358925
(CHEMBL1923682)Show InChI InChI=1S/C16H19N3O3S/c1-22-14-5-6-15-11(10-14)7-8-19(23(18,20)21)16(15)12-3-2-4-13(17)9-12/h2-6,9-10,16H,7-8,17H2,1H3,(H2,18,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 99.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA2 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50358919
(CHEMBL1923676)Show InChI InChI=1S/C16H17ClN2O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9H2,1H3,(H2,18,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 101 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA1 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50358919
(CHEMBL1923676)Show InChI InChI=1S/C16H17ClN2O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9H2,1H3,(H2,18,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 104 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA2 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50358926
(CHEMBL1923683)Show InChI InChI=1S/C16H19N3O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9,17H2,1H3,(H2,18,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 222 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA2 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50358923
(CHEMBL1923680)Show SMILES COc1ccc2C(N(CCc2c1)S(N)(=O)=O)c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C16H17N3O5S/c1-24-14-5-6-15-11(10-14)7-8-18(25(17,22)23)16(15)12-3-2-4-13(9-12)19(20)21/h2-6,9-10,16H,7-8H2,1H3,(H2,17,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 293 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA2 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50358924
(CHEMBL1923681)Show SMILES COc1ccc2C(N(CCc2c1)S(N)(=O)=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C16H17N3O5S/c1-24-14-6-7-15-12(10-14)8-9-18(25(17,22)23)16(15)11-2-4-13(5-3-11)19(20)21/h2-7,10,16H,8-9H2,1H3,(H2,17,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA2 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50358917
(CHEMBL1923674)Show InChI InChI=1S/C16H18N2O3S/c1-21-14-7-8-15-13(11-14)9-10-18(22(17,19)20)16(15)12-5-3-2-4-6-12/h2-8,11,16H,9-10H2,1H3,(H2,17,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 422 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA2 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50358921
(CHEMBL1923678)Show InChI InChI=1S/C16H17FN2O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9H2,1H3,(H2,18,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 476 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA2 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50358922
(CHEMBL1923679)Show InChI InChI=1S/C17H20N2O3S/c1-12-3-5-13(6-4-12)17-16-8-7-15(22-2)11-14(16)9-10-19(17)23(18,20)21/h3-8,11,17H,9-10H2,1-2H3,(H2,18,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 957 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA1 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50358920
(CHEMBL1923677)Show SMILES COc1ccc2C(N(CCc2c1)S(N)(=O)=O)c1ccc(cc1)C#N Show InChI InChI=1S/C17H17N3O3S/c1-23-15-6-7-16-14(10-15)8-9-20(24(19,21)22)17(16)13-4-2-12(11-18)3-5-13/h2-7,10,17H,8-9H2,1H3,(H2,19,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 995 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA1 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50358923
(CHEMBL1923680)Show SMILES COc1ccc2C(N(CCc2c1)S(N)(=O)=O)c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C16H17N3O5S/c1-24-14-5-6-15-11(10-14)7-8-18(25(17,22)23)16(15)12-3-2-4-13(9-12)19(20)21/h2-6,9-10,16H,7-8H2,1H3,(H2,17,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA1 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50358918
(CHEMBL1923675)Show InChI InChI=1S/C16H17BrN2O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9H2,1H3,(H2,18,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA2 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50358918
(CHEMBL1923675)Show InChI InChI=1S/C16H17BrN2O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9H2,1H3,(H2,18,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA1 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50358926
(CHEMBL1923683)Show InChI InChI=1S/C16H19N3O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9,17H2,1H3,(H2,18,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA1 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50358925
(CHEMBL1923682)Show InChI InChI=1S/C16H19N3O3S/c1-22-14-5-6-15-11(10-14)7-8-19(23(18,20)21)16(15)12-3-2-4-13(17)9-12/h2-6,9-10,16H,7-8,17H2,1H3,(H2,18,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA1 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50358921
(CHEMBL1923678)Show InChI InChI=1S/C16H17FN2O3S/c1-22-14-6-7-15-12(10-14)8-9-19(23(18,20)21)16(15)11-2-4-13(17)5-3-11/h2-7,10,16H,8-9H2,1H3,(H2,18,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA1 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50358924
(CHEMBL1923681)Show SMILES COc1ccc2C(N(CCc2c1)S(N)(=O)=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C16H17N3O5S/c1-24-14-6-7-15-12(10-14)8-9-18(25(17,22)23)16(15)11-2-4-13(5-3-11)19(20)21/h2-7,10,16H,8-9H2,1H3,(H2,17,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA1 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM10888
(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)Show InChI InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
Article
PubMed
| 5.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50358917
(CHEMBL1923674)Show InChI InChI=1S/C16H18N2O3S/c1-21-14-7-8-15-13(11-14)9-10-18(22(17,19)20)16(15)12-5-3-2-4-6-12/h2-8,11,16H,9-10H2,1H3,(H2,17,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Messina
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant full length CA1 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 7003-7 (2011)
Article DOI: 10.1016/j.bmc.2011.10.015
BindingDB Entry DOI: 10.7270/Q2C24WV6 |
More data for this
Ligand-Target Pair | |
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