Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50423841 (CHEMBL1934635) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ catholique de Louvain (UCL) Curated by ChEMBL | Assay Description Inhibition of alpha4beta1 integrin expressed in human CCRF-CEM cells assessed as cell adhesion to fibronectin after 1 hr by fluorimetry analysis | Bioorg Med Chem Lett 22: 586-90 (2011) Article DOI: 10.1016/j.bmcl.2011.10.078 BindingDB Entry DOI: 10.7270/Q22808WZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50423845 (CHEMBL1934639) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ catholique de Louvain (UCL) Curated by ChEMBL | Assay Description Inhibition of alpha4beta1 integrin expressed in human CCRF-CEM cells assessed as cell adhesion to fibronectin after 1 hr by fluorimetry analysis | Bioorg Med Chem Lett 22: 586-90 (2011) Article DOI: 10.1016/j.bmcl.2011.10.078 BindingDB Entry DOI: 10.7270/Q22808WZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50423840 (CHEMBL1934634) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.63E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ catholique de Louvain (UCL) Curated by ChEMBL | Assay Description Inhibition of alpha4beta1 integrin expressed in human CCRF-CEM cells assessed as cell adhesion to fibronectin after 1 hr by fluorimetry analysis | Bioorg Med Chem Lett 22: 586-90 (2011) Article DOI: 10.1016/j.bmcl.2011.10.078 BindingDB Entry DOI: 10.7270/Q22808WZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50423842 (CHEMBL1934636) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ catholique de Louvain (UCL) Curated by ChEMBL | Assay Description Inhibition of alpha4beta1 integrin expressed in human CCRF-CEM cells assessed as cell adhesion to fibronectin after 1 hr by fluorimetry analysis | Bioorg Med Chem Lett 22: 586-90 (2011) Article DOI: 10.1016/j.bmcl.2011.10.078 BindingDB Entry DOI: 10.7270/Q22808WZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50423839 (CHEMBL1934744) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ catholique de Louvain (UCL) Curated by ChEMBL | Assay Description Inhibition of alpha4beta1 integrin expressed in human CCRF-CEM cells assessed as cell adhesion to fibronectin after 1 hr by fluorimetry analysis | Bioorg Med Chem Lett 22: 586-90 (2011) Article DOI: 10.1016/j.bmcl.2011.10.078 BindingDB Entry DOI: 10.7270/Q22808WZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50423843 (CHEMBL1934637) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.23E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ catholique de Louvain (UCL) Curated by ChEMBL | Assay Description Inhibition of alpha4beta1 integrin expressed in human CCRF-CEM cells assessed as cell adhesion to fibronectin after 1 hr by fluorimetry analysis | Bioorg Med Chem Lett 22: 586-90 (2011) Article DOI: 10.1016/j.bmcl.2011.10.078 BindingDB Entry DOI: 10.7270/Q22808WZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50423838 (CHEMBL1934743) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.51E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ catholique de Louvain (UCL) Curated by ChEMBL | Assay Description Inhibition of alpha4beta1 integrin expressed in human CCRF-CEM cells assessed as cell adhesion to fibronectin after 1 hr by fluorimetry analysis | Bioorg Med Chem Lett 22: 586-90 (2011) Article DOI: 10.1016/j.bmcl.2011.10.078 BindingDB Entry DOI: 10.7270/Q22808WZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50423844 (CHEMBL1934638) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ catholique de Louvain (UCL) Curated by ChEMBL | Assay Description Inhibition of alpha4beta1 integrin expressed in human CCRF-CEM cells assessed as cell adhesion to fibronectin after 1 hr by fluorimetry analysis | Bioorg Med Chem Lett 22: 586-90 (2011) Article DOI: 10.1016/j.bmcl.2011.10.078 BindingDB Entry DOI: 10.7270/Q22808WZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50423846 (CHEMBL1934742) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ catholique de Louvain (UCL) Curated by ChEMBL | Assay Description Inhibition of alpha4beta1 integrin expressed in human CCRF-CEM cells assessed as cell adhesion to fibronectin after 1 hr by fluorimetry analysis | Bioorg Med Chem Lett 22: 586-90 (2011) Article DOI: 10.1016/j.bmcl.2011.10.078 BindingDB Entry DOI: 10.7270/Q22808WZ | |||||||||||
More data for this Ligand-Target Pair |