Affinity Data by PubMed id=22118829

PubMed code 22118829

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50006811 (2-(12-Hydroxy-5,10-dodecadiynyl)-3,5,6-trimethyl-p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Curated by ChEMBL					Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec...				Eur J Med Chem 47: 351-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW
University of Hyderabad Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50359871 (CHEMBL1929096) Show SMILES CSc1ccc(COCC#CC(O)c2ccc(cc2)C(C)C)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Curated by ChEMBL					Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec...				Eur J Med Chem 47: 351-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW
University of Hyderabad Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50359870 (CHEMBL1929095) Show SMILES CSc1ccc(COCC#CC(O)c2ccc(F)cc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Curated by ChEMBL					Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec...				Eur J Med Chem 47: 351-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW
University of Hyderabad Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50359868 (CHEMBL1929093) Show SMILES CSc1ccc(COCC#CC(O)c2ccc(cc2)C#N)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Curated by ChEMBL					Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec...				Eur J Med Chem 47: 351-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW
University of Hyderabad Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50359869 (CHEMBL1929094) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Curated by ChEMBL					Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec...				Eur J Med Chem 47: 351-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW
University of Hyderabad Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50359864 (CHEMBL1929089) Show SMILES COc1cccc(C(O)C#CCOCc2ccc(SC)cc2)c1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Curated by ChEMBL					Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec...				Eur J Med Chem 47: 351-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW
University of Hyderabad Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50359865 (CHEMBL1929090) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Curated by ChEMBL					Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec...				Eur J Med Chem 47: 351-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW
University of Hyderabad Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50359866 (CHEMBL1929091) Show SMILES COc1ccc(cc1OC)C(O)C#CCOCc1ccc(SC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Curated by ChEMBL					Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec...				Eur J Med Chem 47: 351-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW
University of Hyderabad Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50359867 (CHEMBL1929092) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Curated by ChEMBL					Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec...				Eur J Med Chem 47: 351-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW
University of Hyderabad Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50359861 (CHEMBL1929086) Show SMILES OC(C#CCOCc1ccccc1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Curated by ChEMBL					Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec...				Eur J Med Chem 47: 351-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW
University of Hyderabad Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50359862 (CHEMBL1929087) Show SMILES CCCCCC(O)C#CCOCc1ccc(SC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Curated by ChEMBL					Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec...				Eur J Med Chem 47: 351-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW
University of Hyderabad Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50359863 (CHEMBL1929088) Show SMILES COc1ccc(cc1)C(O)C#CCOCc1ccc(SC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Curated by ChEMBL					Assay Description Inhibition of 5-LOX assessed as decrease in oxygen concentration using arachidonic acid as substrate by polarigraphic method with Clark's oxygen elec...				Eur J Med Chem 47: 351-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW
University of Hyderabad Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50359860 (CHEMBL1929097) Show SMILES CCCC(O)C#CCOCc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Curated by ChEMBL					Assay Description Inhibition of 5-LOX				Eur J Med Chem 47: 351-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.003 BindingDB Entry DOI: 10.7270/Q2TT4RCW
University of Hyderabad Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%