Found 31 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50361993
(CHEMBL1939700)Show InChI InChI=1S/C20H21F2NO/c21-13-19-17-3-1-2-4-18(17)20(24-19)9-11-23(12-10-20)14-15-5-7-16(22)8-6-15/h1-8,19H,9-14H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation counting |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)Show InChI InChI=1S/C21H24FNO/c22-13-10-20-18-8-4-5-9-19(18)21(24-20)11-14-23(15-12-21)16-17-6-2-1-3-7-17/h1-9,20H,10-16H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation counting |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50361998
(CHEMBL1939698)Show InChI InChI=1S/C20H22FNO/c21-14-19-17-8-4-5-9-18(17)20(23-19)10-12-22(13-11-20)15-16-6-2-1-3-7-16/h1-9,19H,10-15H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.740 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation counting |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Vesicular acetylcholine transporter
(Homo sapiens (Human)) | BDBM50361992
(CHEMBL1939699)Show InChI InChI=1S/C23H28FNO/c24-15-7-6-12-22-20-10-4-5-11-21(20)23(26-22)13-16-25(17-14-23)18-19-8-2-1-3-9-19/h1-5,8-11,22H,6-7,12-18H2 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to VAChT |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Vesicular acetylcholine transporter
(Homo sapiens (Human)) | BDBM50299280
(1'-benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofura...)Show InChI InChI=1S/C22H26FNO/c23-14-6-11-21-19-9-4-5-10-20(19)22(25-21)12-15-24(16-13-22)17-18-7-2-1-3-8-18/h1-5,7-10,21H,6,11-17H2 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to VAChT |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50361994
(CHEMBL1939701)Show InChI InChI=1S/C20H22FNO/c1-15-18-4-2-3-5-19(18)20(23-15)10-12-22(13-11-20)14-16-6-8-17(21)9-7-16/h2-9,15H,10-14H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation counting |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50361992
(CHEMBL1939699)Show InChI InChI=1S/C23H28FNO/c24-15-7-6-12-22-20-10-4-5-11-21(20)23(26-22)13-16-25(17-14-23)18-19-8-2-1-3-9-19/h1-5,8-11,22H,6-7,12-18H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation counting |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50299280
(1'-benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofura...)Show InChI InChI=1S/C22H26FNO/c23-14-6-11-21-19-9-4-5-10-20(19)22(25-21)12-15-24(16-13-22)17-18-7-2-1-3-8-18/h1-5,7-10,21H,6,11-17H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation counting |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Vesicular acetylcholine transporter
(Homo sapiens (Human)) | BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)Show InChI InChI=1S/C21H24FNO/c22-13-10-20-18-8-4-5-9-19(18)21(24-20)11-14-23(15-12-21)16-17-6-2-1-3-7-17/h1-9,20H,10-16H2 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to VAChT |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
(Homo sapiens (Human)) | BDBM50338990
(1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piper...)Show InChI InChI=1S/C23H32N2O2/c1-26-22-11-10-21(19-23(22)27-2)12-14-25-17-15-24(16-18-25)13-6-9-20-7-4-3-5-8-20/h3-5,7-8,10-11,19H,6,9,12-18H2,1-2H3 | PDB
Reactome pathway
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MCE
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PC sid
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| Article
PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to EBP |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50361997
(CHEMBL1939704)Show SMILES Cc1ccc(cc1)S(=O)(=O)OCC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc12 Show InChI InChI=1S/C27H29NO4S/c1-21-11-13-23(14-12-21)33(29,30)31-20-26-24-9-5-6-10-25(24)27(32-26)15-17-28(18-16-27)19-22-7-3-2-4-8-22/h2-14,26H,15-20H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation counting |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50361995
(CHEMBL1939702)Show InChI InChI=1S/C21H24FNO/c1-16(17-7-3-2-4-8-17)23-13-11-21(12-14-23)19-10-6-5-9-18(19)20(15-22)24-21/h2-10,16,20H,11-15H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation counting |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50120482
(1'-benzylspiro[1,3-dihydroisobenzofuran-1,4'-(hexa...)Show InChI InChI=1S/C20H23NO2/c22-15-19-17-8-4-5-9-18(17)20(23-19)10-12-21(13-11-20)14-16-6-2-1-3-7-16/h1-9,19,22H,10-15H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation counting |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50035131
((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)Show SMILES [#6]-[#6@@H]1-[#6@@H]-2-[#6]-c3ccc(-[#8])cc3[C@@]1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](/[#6])-[#6] |r,TLB:16:15:10.4.3:1| Show InChI InChI=1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation counting |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 | PDB
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| Purchase
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| PDB
Article
PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation counting |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50361996
(CHEMBL1939703)Show InChI InChI=1S/C21H25NO/c1-16(18-8-4-3-5-9-18)22-14-12-21(13-15-22)20-11-7-6-10-19(20)17(2)23-21/h3-11,16-17H,12-15H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation counting |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50361998
(CHEMBL1939698)Show InChI InChI=1S/C20H22FNO/c21-14-19-17-8-4-5-9-18(17)20(23-19)10-12-22(13-11-20)15-16-6-2-1-3-7-16/h1-9,19H,10-15H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 152 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to delta opioid receptor |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50299280
(1'-benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofura...)Show InChI InChI=1S/C22H26FNO/c23-14-6-11-21-19-9-4-5-10-20(19)22(25-21)12-15-24(16-13-22)17-18-7-2-1-3-8-18/h1-5,7-10,21H,6,11-17H2 | PDB
Reactome pathway
KEGG
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 209 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to delta opioid receptor |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
(Homo sapiens (Human)) | BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)Show InChI InChI=1S/C21H24FNO/c22-13-10-20-18-8-4-5-9-19(18)21(24-20)11-14-23(15-12-21)16-17-6-2-1-3-7-17/h1-9,20H,10-16H2 | PDB
Reactome pathway
KEGG
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 211 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to EBP |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
(Homo sapiens (Human)) | BDBM50361992
(CHEMBL1939699)Show InChI InChI=1S/C23H28FNO/c24-15-7-6-12-22-20-10-4-5-11-21(20)23(26-22)13-16-25(17-14-23)18-19-8-2-1-3-9-19/h1-5,8-11,22H,6-7,12-18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 233 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to EBP |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50299280
(1'-benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofura...)Show InChI InChI=1S/C22H26FNO/c23-14-6-11-21-19-9-4-5-10-20(19)22(25-21)12-15-24(16-13-22)17-18-7-2-1-3-8-18/h1-5,7-10,21H,6,11-17H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 246 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to mu opioid receptor |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50299280
(1'-benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofura...)Show InChI InChI=1S/C22H26FNO/c23-14-6-11-21-19-9-4-5-10-20(19)22(25-21)12-15-24(16-13-22)17-18-7-2-1-3-8-18/h1-5,7-10,21H,6,11-17H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 368 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to kappa opioid receptor |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)Show InChI InChI=1S/C21H24FNO/c22-13-10-20-18-8-4-5-9-19(18)21(24-20)11-14-23(15-12-21)16-17-6-2-1-3-7-17/h1-9,20H,10-16H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 372 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to kappa opioid receptor |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50361992
(CHEMBL1939699)Show InChI InChI=1S/C23H28FNO/c24-15-7-6-12-22-20-10-4-5-11-21(20)23(26-22)13-16-25(17-14-23)18-19-8-2-1-3-9-19/h1-5,8-11,22H,6-7,12-18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 419 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to kappa opioid receptor |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
(Homo sapiens (Human)) | BDBM50299280
(1'-benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofura...)Show InChI InChI=1S/C22H26FNO/c23-14-6-11-21-19-9-4-5-10-20(19)22(25-21)12-15-24(16-13-22)17-18-7-2-1-3-8-18/h1-5,7-10,21H,6,11-17H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 455 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to EBP |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)Show InChI InChI=1S/C21H24FNO/c22-13-10-20-18-8-4-5-9-19(18)21(24-20)11-14-23(15-12-21)16-17-6-2-1-3-7-17/h1-9,20H,10-16H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 456 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to mu opioid receptor |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50361998
(CHEMBL1939698)Show InChI InChI=1S/C20H22FNO/c21-14-19-17-8-4-5-9-18(17)20(23-19)10-12-22(13-11-20)15-16-6-2-1-3-7-16/h1-9,19H,10-15H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 481 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to mu opioid receptor |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50361992
(CHEMBL1939699)Show InChI InChI=1S/C23H28FNO/c24-15-7-6-12-22-20-10-4-5-11-21(20)23(26-22)13-16-25(17-14-23)18-19-8-2-1-3-9-19/h1-5,8-11,22H,6-7,12-18H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 605 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to mu opioid receptor |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50361998
(CHEMBL1939698)Show InChI InChI=1S/C20H22FNO/c21-14-19-17-8-4-5-9-18(17)20(23-19)10-12-22(13-11-20)15-16-6-2-1-3-7-16/h1-9,19H,10-15H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 918 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to kappa opioid receptor |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50361992
(CHEMBL1939699)Show InChI InChI=1S/C23H28FNO/c24-15-7-6-12-22-20-10-4-5-11-21(20)23(26-22)13-16-25(17-14-23)18-19-8-2-1-3-9-19/h1-5,8-11,22H,6-7,12-18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to delta opioid receptor |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50334158
(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)Show InChI InChI=1S/C21H24FNO/c22-13-10-20-18-8-4-5-9-19(18)21(24-20)11-14-23(15-12-21)16-17-6-2-1-3-7-17/h1-9,20H,10-16H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy
Curated by ChEMBL
| Assay Description
Binding affinity to delta opioid receptor |
Bioorg Med Chem 20: 257-69 (2011)
Article DOI: 10.1016/j.bmc.2011.11.002
BindingDB Entry DOI: 10.7270/Q2NG4R2V |
More data for this
Ligand-Target Pair | |
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