Affinity Data by PubMed id=22191331

PubMed code 22191331

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50394680 (CHEMBL1939222) Show SMILES Clc1cc(Cl)cc(OCc2cc(=O)[nH][nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibition of CYP2C19				J Med Chem 55: 515-27 (2012) Article DOI: 10.1021/jm2014277 BindingDB Entry DOI: 10.7270/Q2S75HF3
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50394680 (CHEMBL1939222) Show SMILES Clc1cc(Cl)cc(OCc2cc(=O)[nH][nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibition of CYP2C9				J Med Chem 55: 515-27 (2012) Article DOI: 10.1021/jm2014277 BindingDB Entry DOI: 10.7270/Q2S75HF3
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50394680 (CHEMBL1939222) Show SMILES Clc1cc(Cl)cc(OCc2cc(=O)[nH][nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibition of CYP1A2				J Med Chem 55: 515-27 (2012) Article DOI: 10.1021/jm2014277 BindingDB Entry DOI: 10.7270/Q2S75HF3
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50394680 (CHEMBL1939222) Show SMILES Clc1cc(Cl)cc(OCc2cc(=O)[nH][nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibition of CYP3A4 using midazolam as substrate				J Med Chem 55: 515-27 (2012) Article DOI: 10.1021/jm2014277 BindingDB Entry DOI: 10.7270/Q2S75HF3
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50394680 (CHEMBL1939222) Show SMILES Clc1cc(Cl)cc(OCc2cc(=O)[nH][nH]2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibition of CYP2D6				J Med Chem 55: 515-27 (2012) Article DOI: 10.1021/jm2014277 BindingDB Entry DOI: 10.7270/Q2S75HF3
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50394680 (CHEMBL1939222) Show SMILES Clc1cc(Cl)cc(OCc2cc(=O)[nH][nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibition of CYP3A4 using testosterone as substrate				J Med Chem 55: 515-27 (2012) Article DOI: 10.1021/jm2014277 BindingDB Entry DOI: 10.7270/Q2S75HF3
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%