BindingDB logo
myBDB logout

PubMed code 22200597

Compile data set for download or QSAR
Found 33 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362477
PNG
(CHEMBL1940857)
Show SMILES Cc1ccc2cc(\C=C\C(=O)c3cc(Cl)sc3Cl)c(Cl)nc2c1
Show InChI InChI=1S/C17H10Cl3NOS/c1-9-2-3-10-7-11(16(19)21-13(10)6-9)4-5-14(22)12-8-15(18)23-17(12)20/h2-8H,1H3/b5-4+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 73.4n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362499
PNG
(CHEMBL1940846)
Show SMILES Cc1ccc2nc(Cl)c(\C=C\C(=O)c3cc(Cl)sc3Cl)cc2c1
Show InChI InChI=1S/C17H10Cl3NOS/c1-9-2-4-13-11(6-9)7-10(16(19)21-13)3-5-14(22)12-8-15(18)23-17(12)20/h2-8H,1H3/b5-3+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 81.4n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362475
PNG
(CHEMBL1940855)
Show SMILES Cc1ccc2cc(\C=C\C(=O)c3sccc3Cl)c(Cl)nc2c1
Show InChI InChI=1S/C17H11Cl2NOS/c1-10-2-3-11-9-12(17(19)20-14(11)8-10)4-5-15(21)16-13(18)6-7-22-16/h2-9H,1H3/b5-4+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 82.7n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362497
PNG
(CHEMBL1940844)
Show SMILES Cc1ccc2nc(Cl)c(\C=C\C(=O)c3sccc3Cl)cc2c1
Show InChI InChI=1S/C17H11Cl2NOS/c1-10-2-4-14-12(8-10)9-11(17(19)20-14)3-5-15(21)16-13(18)6-7-22-16/h2-9H,1H3/b5-3+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 87.1n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362476
PNG
(CHEMBL1940856)
Show SMILES Cc1ccc2cc(\C=C\C(=O)c3ccc(Cl)s3)c(Cl)nc2c1
Show InChI InChI=1S/C17H11Cl2NOS/c1-10-2-3-11-9-12(17(19)20-13(11)8-10)4-5-14(21)15-6-7-16(18)22-15/h2-9H,1H3/b5-4+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 92.2n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362479
PNG
(CHEMBL1940859)
Show SMILES Cc1ccc2cc(\C=C\C(=O)c3ccc(Br)s3)c(Cl)nc2c1
Show InChI InChI=1S/C17H11BrClNOS/c1-10-2-3-11-9-12(17(19)20-13(11)8-10)4-5-14(21)15-6-7-16(18)22-15/h2-9H,1H3/b5-4+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 104n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362498
PNG
(CHEMBL1940845)
Show SMILES Cc1ccc2nc(Cl)c(\C=C\C(=O)c3ccc(Cl)s3)cc2c1
Show InChI InChI=1S/C17H11Cl2NOS/c1-10-2-4-13-12(8-10)9-11(17(19)20-13)3-5-14(21)15-6-7-16(18)22-15/h2-9H,1H3/b5-3+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 107n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362478
PNG
(CHEMBL1940858)
Show SMILES Cc1ccc2cc(\C=C\C(=O)c3sccc3Br)c(Cl)nc2c1
Show InChI InChI=1S/C17H11BrClNOS/c1-10-2-3-11-9-12(17(19)20-14(11)8-10)4-5-15(21)16-13(18)6-7-22-16/h2-9H,1H3/b5-4+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 112n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362501
PNG
(CHEMBL1940848)
Show SMILES Cc1ccc2nc(Cl)c(\C=C\C(=O)c3ccc(Br)s3)cc2c1
Show InChI InChI=1S/C17H11BrClNOS/c1-10-2-4-13-12(8-10)9-11(17(19)20-13)3-5-14(21)15-6-7-16(18)22-15/h2-9H,1H3/b5-3+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 113n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362500
PNG
(CHEMBL1940847)
Show SMILES Cc1ccc2nc(Cl)c(\C=C\C(=O)c3sccc3Br)cc2c1
Show InChI InChI=1S/C17H11BrClNOS/c1-10-2-4-14-12(8-10)9-11(17(19)20-14)3-5-15(21)16-13(18)6-7-22-16/h2-9H,1H3/b5-3+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 129n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362506
PNG
(CHEMBL1940853)
Show SMILES Cc1ccc(s1)C(=O)\C=C\c1cc2ccc(C)cc2nc1Cl
Show InChI InChI=1S/C18H14ClNOS/c1-11-3-5-13-10-14(18(19)20-15(13)9-11)6-7-16(21)17-8-4-12(2)22-17/h3-10H,1-2H3/b7-6+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 130n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362486
PNG
(CHEMBL1940866)
Show SMILES Cc1cccc2cc(\C=C\C(=O)c3sccc3Cl)c(Cl)nc12
Show InChI InChI=1S/C17H11Cl2NOS/c1-10-3-2-4-11-9-12(17(19)20-15(10)11)5-6-14(21)16-13(18)7-8-22-16/h2-9H,1H3/b6-5+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 130n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362505
PNG
(CHEMBL1940852)
Show SMILES Cc1csc(c1)C(=O)\C=C\c1cc2ccc(C)cc2nc1Cl
Show InChI InChI=1S/C18H14ClNOS/c1-11-3-4-13-9-14(18(19)20-15(13)7-11)5-6-16(21)17-8-12(2)10-22-17/h3-10H,1-2H3/b6-5+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 139n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362480
PNG
(CHEMBL1940860)
Show SMILES Cc1ccc2cc(\C=C\C(=O)c3ccc(I)s3)c(Cl)nc2c1
Show InChI InChI=1S/C17H11ClINOS/c1-10-2-3-11-9-12(17(18)20-13(11)8-10)4-5-14(21)15-6-7-16(19)22-15/h2-9H,1H3/b5-4+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 148n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362502
PNG
(CHEMBL1940849)
Show SMILES Cc1ccc2nc(Cl)c(\C=C\C(=O)c3ccc(I)s3)cc2c1
Show InChI InChI=1S/C17H11ClINOS/c1-10-2-4-13-12(8-10)9-11(17(18)20-13)3-5-14(21)15-6-7-16(19)22-15/h2-9H,1H3/b5-3+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 154n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362504
PNG
(CHEMBL1940851)
Show SMILES Cc1ccsc1C(=O)C=Cc1cc2ccc(C)cc2nc1Cl |w:9.10|
Show InChI InChI=1S/C18H14ClNOS/c1-11-3-4-13-10-14(18(19)20-15(13)9-11)5-6-16(21)17-12(2)7-8-22-17/h3-10H,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 157n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362494
PNG
(CHEMBL1938421)
Show SMILES Cc1csc(c1)C(=O)\C=C\c1cc2cc(C)ccc2nc1Cl
Show InChI InChI=1S/C18H14ClNOS/c1-11-3-5-15-14(7-11)9-13(18(19)20-15)4-6-16(21)17-8-12(2)10-22-17/h3-10H,1-2H3/b6-4+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 169n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362495
PNG
(CHEMBL1940842)
Show SMILES Cc1ccc(s1)C(=O)\C=C\c1cc2cc(C)ccc2nc1Cl
Show InChI InChI=1S/C18H14ClNOS/c1-11-3-6-15-14(9-11)10-13(18(19)20-15)5-7-16(21)17-8-4-12(2)22-17/h3-10H,1-2H3/b7-5+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 176n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362493
PNG
(CHEMBL1940841)
Show SMILES Cc1ccsc1C(=O)C=Cc1cc2cc(C)ccc2nc1Cl |w:9.10|
Show InChI InChI=1S/C18H14ClNOS/c1-11-3-5-15-14(9-11)10-13(18(19)20-15)4-6-16(21)17-12(2)7-8-22-17/h3-10H,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 185n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362487
PNG
(CHEMBL1940867)
Show SMILES Cc1cccc2cc(\C=C\C(=O)c3ccc(Cl)s3)c(Cl)nc12
Show InChI InChI=1S/C17H11Cl2NOS/c1-10-3-2-4-11-9-12(17(19)20-16(10)11)5-6-13(21)14-7-8-15(18)22-14/h2-9H,1H3/b6-5+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 189n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362503
PNG
(CHEMBL1940850)
Show SMILES Cc1ccc2cc(\C=C\C(=O)c3ccsc3)c(Cl)nc2c1
Show InChI InChI=1S/C17H12ClNOS/c1-11-2-3-12-9-13(17(18)19-15(12)8-11)4-5-16(20)14-6-7-21-10-14/h2-10H,1H3/b5-4+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 208n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362483
PNG
(CHEMBL1940863)
Show SMILES Cc1csc(c1)C(=O)\C=C\c1cc2cccc(C)c2nc1Cl
Show InChI InChI=1S/C18H14ClNOS/c1-11-8-16(22-10-11)15(21)7-6-14-9-13-5-3-4-12(2)17(13)20-18(14)19/h3-10H,1-2H3/b7-6+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 233n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362484
PNG
(CHEMBL1940864)
Show SMILES Cc1ccc(s1)C(=O)\C=C\c1cc2cccc(C)c2nc1Cl
Show InChI InChI=1S/C18H14ClNOS/c1-11-4-3-5-13-10-14(18(19)20-17(11)13)7-8-15(21)16-9-6-12(2)22-16/h3-10H,1-2H3/b8-7+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 262n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362482
PNG
(CHEMBL1940862)
Show SMILES Cc1ccsc1C(=O)C=Cc1cc2cccc(C)c2nc1Cl |w:9.10|
Show InChI InChI=1S/C18H14ClNOS/c1-11-4-3-5-13-10-14(18(19)20-16(11)13)6-7-15(21)17-12(2)8-9-22-17/h3-10H,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 267n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362492
PNG
(CHEMBL1940718)
Show SMILES Cc1ccc2nc(Cl)c(\C=C\C(=O)c3ccsc3)cc2c1
Show InChI InChI=1S/C17H12ClNOS/c1-11-2-4-15-14(8-11)9-12(17(18)19-15)3-5-16(20)13-6-7-21-10-13/h2-10H,1H3/b5-3+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 287n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362489
PNG
(CHEMBL1940869)
Show SMILES Cc1cccc2cc(\C=C\C(=O)c3sccc3Br)c(Cl)nc12
Show InChI InChI=1S/C17H11BrClNOS/c1-10-3-2-4-11-9-12(17(19)20-15(10)11)5-6-14(21)16-13(18)7-8-22-16/h2-9H,1H3/b6-5+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 313n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362488
PNG
(CHEMBL1940868)
Show SMILES Cc1cccc2cc(\C=C\C(=O)c3cc(Cl)sc3Cl)c(Cl)nc12
Show InChI InChI=1S/C17H10Cl3NOS/c1-9-3-2-4-10-7-11(16(19)21-15(9)10)5-6-13(22)12-8-14(18)23-17(12)20/h2-8H,1H3/b6-5+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 358n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362490
PNG
(CHEMBL1940870)
Show SMILES Cc1cccc2cc(\C=C\C(=O)c3ccc(Br)s3)c(Cl)nc12
Show InChI InChI=1S/C17H11BrClNOS/c1-10-3-2-4-11-9-12(17(19)20-16(10)11)5-6-13(21)14-7-8-15(18)22-14/h2-9H,1H3/b6-5+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 367n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362481
PNG
(CHEMBL1940861)
Show SMILES Cc1cccc2cc(\C=C\C(=O)c3ccsc3)c(Cl)nc12
Show InChI InChI=1S/C17H12ClNOS/c1-11-3-2-4-12-9-13(17(18)19-16(11)12)5-6-15(20)14-7-8-21-10-14/h2-10H,1H3/b6-5+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 389n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362496
PNG
(CHEMBL1940843)
Show SMILES Cc1cc(C(=O)C=Cc2cc3cc(C)ccc3nc2Cl)c(C)s1 |w:7.7|
Show InChI InChI=1S/C19H16ClNOS/c1-11-4-6-17-15(8-11)10-14(19(20)21-17)5-7-18(22)16-9-12(2)23-13(16)3/h4-10H,1-3H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 453n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362491
PNG
(CHEMBL1940871)
Show SMILES Cc1cccc2cc(\C=C\C(=O)c3ccc(I)s3)c(Cl)nc12
Show InChI InChI=1S/C17H11ClINOS/c1-10-3-2-4-11-9-12(17(18)20-16(10)11)5-6-13(21)14-7-8-15(19)22-14/h2-9H,1H3/b6-5+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 482n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362474
PNG
(CHEMBL1940854)
Show SMILES Cc1cc(C(=O)C=Cc2cc3ccc(C)cc3nc2Cl)c(C)s1 |w:7.7|
Show InChI InChI=1S/C19H16ClNOS/c1-11-4-5-14-10-15(19(20)21-17(14)8-11)6-7-18(22)16-9-12(2)23-13(16)3/h4-10H,1-3H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 561n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50362485
PNG
(CHEMBL1940865)
Show SMILES Cc1cc(C(=O)C=Cc2cc3cccc(C)c3nc2Cl)c(C)s1 |w:7.7|
Show InChI InChI=1S/C19H16ClNOS/c1-11-5-4-6-14-10-15(19(20)21-18(11)14)7-8-17(22)16-9-12(2)23-13(16)3/h4-10H,1-3H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



University of the Punjab

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay


Bioorg Med Chem Lett 22: 942-4 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.017
BindingDB Entry DOI: 10.7270/Q2DV1K9D
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%