Affinity Data by PubMed id=22204908

PubMed code 22204908

Found 22 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cathepsin D (Homo sapiens (Human))	BDBM50362536 (CHEMBL1941013) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Plasmepsin II (Plasmodium falciparum)	BDBM50362535 (CHEMBL1941012) Show SMILES O=C(Cn1c(nc2ccccc12)-c1ccccn1)c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Plasmepsin II (Plasmodium falciparum)	BDBM50362533 (CHEMBL1941010) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50362537 (CHEMBL1941014) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Plasmepsin II (Plasmodium falciparum)	BDBM50362536 (CHEMBL1941013) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50362532 (CHEMBL1941009) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Plasmepsin II (Plasmodium falciparum)	BDBM50362529 (CHEMBL1941006) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Plasmepsin II (Plasmodium falciparum)	BDBM50362528 (CHEMBL1941005) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50362528 (CHEMBL1941005) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Plasmepsin II (Plasmodium falciparum)	BDBM50362530 (CHEMBL1941007) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50362538 (CHEMBL1941015) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50362529 (CHEMBL1941006) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Plasmepsin II (Plasmodium falciparum)	BDBM50362532 (CHEMBL1941009) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Plasmepsin II (Plasmodium falciparum)	BDBM50362531 (CHEMBL1941008) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50362530 (CHEMBL1941007) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50362533 (CHEMBL1941010) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Plasmepsin II (Plasmodium falciparum)	BDBM50362538 (CHEMBL1941015) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Plasmepsin II (Plasmodium falciparum)	BDBM50362537 (CHEMBL1941014) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50362531 (CHEMBL1941008) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50362535 (CHEMBL1941012) Show SMILES O=C(Cn1c(nc2ccccc12)-c1ccccn1)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50362534 (CHEMBL1941011) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair
Plasmepsin II (Plasmodium falciparum)	BDBM50362534 (CHEMBL1941011) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET analysis				Bioorg Med Chem Lett 22: 1282-6 (2012) Article DOI: 10.1016/j.bmcl.2011.10.018 BindingDB Entry DOI: 10.7270/Q2WS8TPJ
University of Karachi Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%