Affinity Data by PubMed id=22225635

PubMed code 22225635

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM50363399 (CHEMBL1946633) Show SMILES Cc1nc2cc(Cl)c(Cl)cc2n1C1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of CDK9/CyclinT1				Bioorg Med Chem Lett 22: 1317-21 (2012) Article DOI: 10.1016/j.bmcl.2011.12.088 BindingDB Entry DOI: 10.7270/Q2NZ883V
University of Nottingham Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM50363400 (CHEMBL1946636) Show SMILES CC(C)c1nc2cc(Cl)c(Cl)cc2n1C1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of CDK9/CyclinT1				Bioorg Med Chem Lett 22: 1317-21 (2012) Article DOI: 10.1016/j.bmcl.2011.12.088 BindingDB Entry DOI: 10.7270/Q2NZ883V
University of Nottingham Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM50363403 (CHEMBL1946639) Show SMILES CS(=O)(=O)c1nc2cc(Cl)c(Cl)cc2n1C1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of CDK9/CyclinT1				Bioorg Med Chem Lett 22: 1317-21 (2012) Article DOI: 10.1016/j.bmcl.2011.12.088 BindingDB Entry DOI: 10.7270/Q2NZ883V
University of Nottingham Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM50363402 (CHEMBL1946638) Show SMILES CS(=O)c1nc2cc(Cl)c(Cl)cc2n1C1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of CDK9/CyclinT1				Bioorg Med Chem Lett 22: 1317-21 (2012) Article DOI: 10.1016/j.bmcl.2011.12.088 BindingDB Entry DOI: 10.7270/Q2NZ883V
University of Nottingham Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM50363401 (CHEMBL1946637) Show SMILES CSc1nc2cc(Cl)c(Cl)cc2n1C1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of CDK9/CyclinT1				Bioorg Med Chem Lett 22: 1317-21 (2012) Article DOI: 10.1016/j.bmcl.2011.12.088 BindingDB Entry DOI: 10.7270/Q2NZ883V
University of Nottingham Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%