Found 34 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365768
(CHEMBL1956396)Show SMILES CN(C)c1ccc(cc1)-c1nnnn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C16H17N5O2S/c1-20(2)13-6-4-12(5-7-13)16-17-18-19-21(16)14-8-10-15(11-9-14)24(3,22)23/h4-11H,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365760
(CHEMBL1956388)Show SMILES CN(C)c1ccc(cc1)-c1nnnn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C15H16N6O2S/c1-20(2)12-5-3-11(4-6-12)15-17-18-19-21(15)13-7-9-14(10-8-13)24(16,22)23/h3-10H,1-2H3,(H2,16,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365764
(CHEMBL1956392)Show InChI InChI=1S/C14H11FN4O2S/c1-22(20,21)13-8-6-12(7-9-13)19-14(16-17-18-19)10-2-4-11(15)5-3-10/h2-9H,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365753
(CHEMBL1956381)Show InChI InChI=1S/C13H11N5O2S/c14-21(19,20)12-8-6-11(7-9-12)18-13(15-16-17-18)10-4-2-1-3-5-10/h1-9H,(H2,14,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365761
(CHEMBL1956389)Show InChI InChI=1S/C14H12N4O2S/c1-21(19,20)13-9-7-12(8-10-13)18-14(15-16-17-18)11-5-3-2-4-6-11/h2-10H,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365765
(CHEMBL1956393)Show InChI InChI=1S/C14H11ClN4O2S/c1-22(20,21)13-8-6-12(7-9-13)19-14(16-17-18-19)10-2-4-11(15)5-3-10/h2-9H,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365756
(CHEMBL1956384)Show InChI InChI=1S/C13H10FN5O2S/c14-10-3-1-9(2-4-10)13-16-17-18-19(13)11-5-7-12(8-6-11)22(15,20)21/h1-8H,(H2,15,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365757
(CHEMBL1956385)Show InChI InChI=1S/C13H10ClN5O2S/c14-10-3-1-9(2-4-10)13-16-17-18-19(13)11-5-7-12(8-6-11)22(15,20)21/h1-8H,(H2,15,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365767
(CHEMBL1956395)Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nnnc1-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C14H11N5O4S/c1-24(22,23)13-8-6-11(7-9-13)18-14(15-16-17-18)10-2-4-12(5-3-10)19(20)21/h2-9H,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365762
(CHEMBL1956390)Show InChI InChI=1S/C15H14N4O2S/c1-11-3-5-12(6-4-11)15-16-17-18-19(15)13-7-9-14(10-8-13)22(2,20)21/h3-10H,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365758
(CHEMBL1956386)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnnc1-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C14H10F3N5O2S/c15-14(16,17)10-3-1-9(2-4-10)13-19-20-21-22(13)11-5-7-12(8-6-11)25(18,23)24/h1-8H,(H2,18,23,24) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365759
(CHEMBL1956387)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnnc1-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C13H10N6O4S/c14-24(22,23)12-7-5-10(6-8-12)18-13(15-16-17-18)9-1-3-11(4-2-9)19(20)21/h1-8H,(H2,14,22,23) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365766
(CHEMBL1956394)Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nnnc1-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H11F3N4O2S/c1-25(23,24)13-8-6-12(7-9-13)22-14(19-20-21-22)10-2-4-11(5-3-10)15(16,17)18/h2-9H,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365759
(CHEMBL1956387)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnnc1-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C13H10N6O4S/c14-24(22,23)12-7-5-10(6-8-12)18-13(15-16-17-18)9-1-3-11(4-2-9)19(20)21/h1-8H,(H2,14,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365766
(CHEMBL1956394)Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nnnc1-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H11F3N4O2S/c1-25(23,24)13-8-6-12(7-9-13)22-14(19-20-21-22)10-2-4-11(5-3-10)15(16,17)18/h2-9H,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365754
(CHEMBL1956382)Show InChI InChI=1S/C14H13N5O2S/c1-10-2-4-11(5-3-10)14-16-17-18-19(14)12-6-8-13(9-7-12)22(15,20)21/h2-9H,1H3,(H2,15,20,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365757
(CHEMBL1956385)Show InChI InChI=1S/C13H10ClN5O2S/c14-10-3-1-9(2-4-10)13-16-17-18-19(13)11-5-7-12(8-6-11)22(15,20)21/h1-8H,(H2,15,20,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365758
(CHEMBL1956386)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnnc1-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C14H10F3N5O2S/c15-14(16,17)10-3-1-9(2-4-10)13-19-20-21-22(13)11-5-7-12(8-6-11)25(18,23)24/h1-8H,(H2,18,23,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365764
(CHEMBL1956392)Show InChI InChI=1S/C14H11FN4O2S/c1-22(20,21)13-8-6-12(7-9-13)19-14(16-17-18-19)10-2-4-11(15)5-3-10/h2-9H,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365756
(CHEMBL1956384)Show InChI InChI=1S/C13H10FN5O2S/c14-10-3-1-9(2-4-10)13-16-17-18-19(13)11-5-7-12(8-6-11)22(15,20)21/h1-8H,(H2,15,20,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365768
(CHEMBL1956396)Show SMILES CN(C)c1ccc(cc1)-c1nnnn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C16H17N5O2S/c1-20(2)13-6-4-12(5-7-13)16-17-18-19-21(16)14-8-10-15(11-9-14)24(3,22)23/h4-11H,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365765
(CHEMBL1956393)Show InChI InChI=1S/C14H11ClN4O2S/c1-22(20,21)13-8-6-12(7-9-13)19-14(16-17-18-19)10-2-4-11(15)5-3-10/h2-9H,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365755
(CHEMBL1956383)Show InChI InChI=1S/C14H13N5O3S/c1-22-12-6-2-10(3-7-12)14-16-17-18-19(14)11-4-8-13(9-5-11)23(15,20)21/h2-9H,1H3,(H2,15,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365754
(CHEMBL1956382)Show InChI InChI=1S/C14H13N5O2S/c1-10-2-4-11(5-3-10)14-16-17-18-19(14)12-6-8-13(9-7-12)22(15,20)21/h2-9H,1H3,(H2,15,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365767
(CHEMBL1956395)Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nnnc1-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C14H11N5O4S/c1-24(22,23)13-8-6-11(7-9-13)18-14(15-16-17-18)10-2-4-12(5-3-10)19(20)21/h2-9H,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365760
(CHEMBL1956388)Show SMILES CN(C)c1ccc(cc1)-c1nnnn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C15H16N6O2S/c1-20(2)12-5-3-11(4-6-12)15-17-18-19-21(15)13-7-9-14(10-8-13)24(16,22)23/h3-10H,1-2H3,(H2,16,22,23) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365755
(CHEMBL1956383)Show InChI InChI=1S/C14H13N5O3S/c1-22-12-6-2-10(3-7-12)14-16-17-18-19(14)11-4-8-13(9-5-11)23(15,20)21/h2-9H,1H3,(H2,15,20,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365753
(CHEMBL1956381)Show InChI InChI=1S/C13H11N5O2S/c14-21(19,20)12-8-6-11(7-9-12)18-13(15-16-17-18)10-4-2-1-3-5-10/h1-9H,(H2,14,19,20) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50365763
(CHEMBL1956391)Show InChI InChI=1S/C15H14N4O3S/c1-22-13-7-3-11(4-8-13)15-16-17-18-19(15)12-5-9-14(10-6-12)23(2,20)21/h3-10H,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365763
(CHEMBL1956391)Show InChI InChI=1S/C15H14N4O3S/c1-22-13-7-3-11(4-8-13)15-16-17-18-19(15)12-5-9-14(10-6-12)23(2,20)21/h3-10H,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365761
(CHEMBL1956389)Show InChI InChI=1S/C14H12N4O2S/c1-21(19,20)13-9-7-12(8-10-13)18-14(15-16-17-18)11-5-3-2-4-6-11/h2-10H,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50365762
(CHEMBL1956390)Show InChI InChI=1S/C15H14N4O2S/c1-11-3-5-12(6-4-11)15-16-17-18-19(15)13-7-9-14(10-8-13)22(2,20)21/h3-10H,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Competitive inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 22: 2235-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.093 BindingDB Entry DOI: 10.7270/Q2S182ZH |
More data for this Ligand-Target Pair | |