Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393310 (CHEMBL605921) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 186 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393323 (CHEMBL2152120) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 150 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393315 (CHEMBL2152112) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 230 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393322 (CHEMBL2152119) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393313 (CHEMBL2152109) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.14E+3 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393314 (CHEMBL2152110) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Homo sapiens (Human)) | BDBM50393322 (CHEMBL2152119) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 7 expressed in HEK293 cells by Ca+2 assay | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393324 (CHEMBL2152121) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 85 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393311 (CHEMBL2152107) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 617 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393312 (CHEMBL2152108) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 710 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393318 (CHEMBL2152115) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 330 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393319 (CHEMBL2152116) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 320 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393321 (CHEMBL2152118) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393316 (CHEMBL2152113) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393317 (CHEMBL2152114) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 501 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393320 (CHEMBL2152117) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50393325 (CHEMBL2152122) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 250 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Agonist activity at human mGlu 2 expressed in CHO cells assessed as [35S]GTPgammaS binding by liquid scintillation analysis | J Med Chem 55: 2688-701 (2012) Article DOI: 10.1021/jm201561r BindingDB Entry DOI: 10.7270/Q2SN0B2B | |||||||||||
More data for this Ligand-Target Pair |