Found 20 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50385902
(CHEMBL2041596)Show SMILES COc1cc(COC(=O)c2ccc(o2)-c2ccccc2)cc(OC)c1OC Show InChI InChI=1S/C21H20O6/c1-23-18-11-14(12-19(24-2)20(18)25-3)13-26-21(22)17-10-9-16(27-17)15-7-5-4-6-8-15/h4-12H,13H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant PDE7A1 using 5 nM to 2 uM cAMP as substrate by Lineweaver-Burk plot analysis |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50385903
(CHEMBL2041614)Show SMILES COc1cc(CNC(=O)c2ccc(o2)-c2ccc(C)cc2[N+]([O-])=O)cc(OC)c1OC Show InChI InChI=1S/C22H22N2O7/c1-13-5-6-15(16(9-13)24(26)27)17-7-8-18(31-17)22(25)23-12-14-10-19(28-2)21(30-4)20(11-14)29-3/h5-11H,12H2,1-4H3,(H,23,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 7.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant PDE7A1 using 5 nM to 2 uM cAMP as substrate by Lineweaver-Burk plot analysis |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50277784
(CHEMBL484928 | N,N,2-trimethyl-5-nitrobenzenesulfo...)Show InChI InChI=1S/C9H12N2O4S/c1-7-4-5-8(11(12)13)6-9(7)16(14,15)10(2)3/h4-6H,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50385909
(CHEMBL2041586)Show SMILES CCOc1cc(cc(OCC)c1OCC)C(=O)OCc1ccc(o1)-c1ccc(cc1C)[N+]([O-])=O Show InChI InChI=1S/C25H27NO8/c1-5-30-22-13-17(14-23(31-6-2)24(22)32-7-3)25(27)33-15-19-9-11-21(34-19)20-10-8-18(26(28)29)12-16(20)4/h8-14H,5-7,15H2,1-4H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of PDE7A1 |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM77437
(1-({[5-(ethoxycarbonyl)-4-methyl-1,3-thiazol-2-yl]...)Show SMILES CCOC(=O)c1sc(NC(=O)C(CC)OC(=O)C(CC(C)C)NC(=O)c2ccccc2)nc1C Show InChI InChI=1S/C24H31N3O6S/c1-6-18(21(29)27-24-25-15(5)19(34-24)23(31)32-7-2)33-22(30)17(13-14(3)4)26-20(28)16-11-9-8-10-12-16/h8-12,14,17-18H,6-7,13H2,1-5H3,(H,26,28)(H,25,27,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of PDE7A1 |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50385910
(CHEMBL2041587)Show SMILES CC1CCCCC1NC(=O)C(N(CCc1ccccc1Cl)C(=O)CCl)c1ccccc1Cl Show InChI InChI=1S/C25H29Cl3N2O2/c1-17-8-2-7-13-22(17)29-25(32)24(19-10-4-6-12-21(19)28)30(23(31)16-26)15-14-18-9-3-5-11-20(18)27/h3-6,9-12,17,22,24H,2,7-8,13-16H2,1H3,(H,29,32) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of PDE7A1 |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Homo sapiens (Human)) | BDBM50385906
(CHEMBL2041597)Show SMILES COc1cc(COC(=O)c2ccc(o2)-c2ccccc2C(F)(F)F)cc(OC)c1OC Show InChI InChI=1S/C22H19F3O6/c1-27-18-10-13(11-19(28-2)20(18)29-3)12-30-21(26)17-9-8-16(31-17)14-6-4-5-7-15(14)22(23,24)25/h4-11H,12H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50385906
(CHEMBL2041597)Show SMILES COc1cc(COC(=O)c2ccc(o2)-c2ccccc2C(F)(F)F)cc(OC)c1OC Show InChI InChI=1S/C22H19F3O6/c1-27-18-10-13(11-19(28-2)20(18)29-3)12-30-21(26)17-9-8-16(31-17)14-6-4-5-7-15(14)22(23,24)25/h4-11H,12H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50385903
(CHEMBL2041614)Show SMILES COc1cc(CNC(=O)c2ccc(o2)-c2ccc(C)cc2[N+]([O-])=O)cc(OC)c1OC Show InChI InChI=1S/C22H22N2O7/c1-13-5-6-15(16(9-13)24(26)27)17-7-8-18(31-17)22(25)23-12-14-10-19(28-2)21(30-4)20(11-14)29-3/h5-11H,12H2,1-4H3,(H,23,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Homo sapiens (Human)) | BDBM50385908
(CHEMBL2041604)Show SMILES COc1cc(COC(=O)c2ccc(o2)-c2ccc(cc2)[N+]([O-])=O)cc(OC)c1OC Show InChI InChI=1S/C21H19NO8/c1-26-18-10-13(11-19(27-2)20(18)28-3)12-29-21(23)17-9-8-16(30-17)14-4-6-15(7-5-14)22(24)25/h4-11H,12H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Homo sapiens (Human)) | BDBM50385903
(CHEMBL2041614)Show SMILES COc1cc(CNC(=O)c2ccc(o2)-c2ccc(C)cc2[N+]([O-])=O)cc(OC)c1OC Show InChI InChI=1S/C22H22N2O7/c1-13-5-6-15(16(9-13)24(26)27)17-7-8-18(31-17)22(25)23-12-14-10-19(28-2)21(30-4)20(11-14)29-3/h5-11H,12H2,1-4H3,(H,23,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50385902
(CHEMBL2041596)Show SMILES COc1cc(COC(=O)c2ccc(o2)-c2ccccc2)cc(OC)c1OC Show InChI InChI=1S/C21H20O6/c1-23-18-11-14(12-19(24-2)20(18)25-3)13-26-21(22)17-10-9-16(27-17)15-7-5-4-6-8-15/h4-12H,13H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50385907
(CHEMBL2041602)Show SMILES COc1cc(COC(=O)c2ccc(o2)-c2ccc(Cl)cc2[N+]([O-])=O)cc(OC)c1OC Show InChI InChI=1S/C21H18ClNO8/c1-27-18-8-12(9-19(28-2)20(18)29-3)11-30-21(24)17-7-6-16(31-17)14-5-4-13(22)10-15(14)23(25)26/h4-10H,11H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50385905
(CHEMBL2041590)Show SMILES CCOc1cc(cc(OCC)c1OCC)C(=O)OCc1ccc(o1)-c1ccccc1 Show InChI InChI=1S/C24H26O6/c1-4-26-21-14-18(15-22(27-5-2)23(21)28-6-3)24(25)29-16-19-12-13-20(30-19)17-10-8-7-9-11-17/h7-15H,4-6,16H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50385902
(CHEMBL2041596)Show SMILES COc1cc(COC(=O)c2ccc(o2)-c2ccccc2)cc(OC)c1OC Show InChI InChI=1S/C21H20O6/c1-23-18-11-14(12-19(24-2)20(18)25-3)13-26-21(22)17-10-9-16(27-17)15-7-5-4-6-8-15/h4-12H,13H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE4B2 using fluorscein 3',5'-cyclic phosphate after 60 mins by IMAP fluorescence polarization assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50385908
(CHEMBL2041604)Show SMILES COc1cc(COC(=O)c2ccc(o2)-c2ccc(cc2)[N+]([O-])=O)cc(OC)c1OC Show InChI InChI=1S/C21H19NO8/c1-26-18-10-13(11-19(27-2)20(18)28-3)12-29-21(23)17-9-8-16(30-17)14-4-6-15(7-5-14)22(24)25/h4-11H,12H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50385904
(CHEMBL2041589)Show SMILES COc1cc(cc(OC)c1OC)C(=O)OCc1ccc(o1)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C21H19NO8/c1-26-18-10-14(11-19(27-2)20(18)28-3)21(23)29-12-16-8-9-17(30-16)13-4-6-15(7-5-13)22(24)25/h4-11H,12H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Homo sapiens (Human)) | BDBM50385902
(CHEMBL2041596)Show SMILES COc1cc(COC(=O)c2ccc(o2)-c2ccccc2)cc(OC)c1OC Show InChI InChI=1S/C21H20O6/c1-23-18-11-14(12-19(24-2)20(18)25-3)13-26-21(22)17-10-9-16(27-17)15-7-5-4-6-8-15/h4-12H,13H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50385902
(CHEMBL2041596)Show SMILES COc1cc(COC(=O)c2ccc(o2)-c2ccccc2)cc(OC)c1OC Show InChI InChI=1S/C21H20O6/c1-23-18-11-14(12-19(24-2)20(18)25-3)13-26-21(22)17-10-9-16(27-17)15-7-5-4-6-8-15/h4-12H,13H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.63E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE4D3 using fluorscein 3',5'-cyclic phosphate after 60 mins by IMAP fluorescence polarization assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Homo sapiens (Human)) | BDBM50385905
(CHEMBL2041590)Show SMILES CCOc1cc(cc(OCC)c1OCC)C(=O)OCc1ccc(o1)-c1ccccc1 Show InChI InChI=1S/C24H26O6/c1-4-26-21-14-18(15-22(27-5-2)23(21)28-6-3)24(25)29-16-19-12-13-20(30-19)17-10-8-7-9-11-17/h7-15H,4-6,16H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.04E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |