Found 104 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50366138
(CHEMBL1957437)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc2ccccc2c1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C30H28N2O4S2/c33-26(17-20-4-3-7-22(16-20)24-9-8-21-5-1-2-6-23(21)18-24)12-10-25-11-13-28(34)32(25)14-15-37-30-31-27(19-38-30)29(35)36/h1-10,12,16,18-19,25-26,33H,11,13-15,17H2,(H,35,36)/b12-10+/t25-,26+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.0120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50360626
(CHEMBL1933722)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2nc(cs2)C(O)=O)c1 |r| Show InChI InChI=1S/C21H24N2O4S2/c1-14-3-2-4-15(11-14)12-17(24)7-5-16-6-8-19(25)23(16)9-10-28-21-22-18(13-29-21)20(26)27/h2-5,7,11,13,16-17,24H,6,8-10,12H2,1H3,(H,26,27)/b7-5+/t16-,17+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50360628
(CHEMBL1933724)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C18H26N2O4S2/c1-2-3-4-5-14(21)8-6-13-7-9-16(22)20(13)10-11-25-18-19-15(12-26-18)17(23)24/h6,8,12-14,21H,2-5,7,9-11H2,1H3,(H,23,24)/b8-6+/t13-,14-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50360623
(CHEMBL1933719)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCCc2ccc(s2)C(O)=O)c1 |r| Show InChI InChI=1S/C23H27NO4S/c1-16-4-2-5-17(14-16)15-19(25)9-7-18-8-12-22(26)24(18)13-3-6-20-10-11-21(29-20)23(27)28/h2,4-5,7,9-11,14,18-19,25H,3,6,8,12-13,15H2,1H3,(H,27,28)/b9-7+/t18-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50366142
(CHEMBL1957434)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(s1)C(O)=O |r| Show InChI InChI=1S/C22H24ClNO4S/c23-16-4-1-3-15(13-16)14-18(25)8-6-17-7-11-21(26)24(17)12-2-5-19-9-10-20(29-19)22(27)28/h1,3-4,6,8-10,13,17-18,25H,2,5,7,11-12,14H2,(H,27,28)/b8-6+/t17-,18+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50366143
(CHEMBL1957430)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2ccc(s2)C(O)=O)c1 |r| Show InChI InChI=1S/C22H25NO4S2/c1-15-3-2-4-16(13-15)14-18(24)7-5-17-6-9-20(25)23(17)11-12-28-21-10-8-19(29-21)22(26)27/h2-5,7-8,10,13,17-18,24H,6,9,11-12,14H2,1H3,(H,26,27)/b7-5+/t17-,18+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50366137
(CHEMBL1957436)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc(Cl)cc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C26H25ClN2O4S2/c27-20-6-4-18(5-7-20)19-3-1-2-17(14-19)15-22(30)10-8-21-9-11-24(31)29(21)12-13-34-26-28-23(16-35-26)25(32)33/h1-8,10,14,16,21-22,30H,9,11-13,15H2,(H,32,33)/b10-8+/t21-,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.810 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50360622
(CHEMBL1933718)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCc2ccc(cc2)C(O)=O)c1 |r| Show InChI InChI=1S/C24H27NO4/c1-17-3-2-4-19(15-17)16-22(26)11-9-21-10-12-23(27)25(21)14-13-18-5-7-20(8-6-18)24(28)29/h2-9,11,15,21-22,26H,10,12-14,16H2,1H3,(H,28,29)/b11-9+/t21-,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50366136
(CHEMBL1957435)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccccc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C26H26N2O4S2/c29-22(16-18-5-4-8-20(15-18)19-6-2-1-3-7-19)11-9-21-10-12-24(30)28(21)13-14-33-26-27-23(17-34-26)25(31)32/h1-9,11,15,17,21-22,29H,10,12-14,16H2,(H,31,32)/b11-9+/t21-,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.940 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50360629
(CHEMBL1933725)Show SMILES O[C@@H](Cc1ccccc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H22N2O4S2/c23-16(12-14-4-2-1-3-5-14)8-6-15-7-9-18(24)22(15)10-11-27-20-21-17(13-28-20)19(25)26/h1-6,8,13,15-16,23H,7,9-12H2,(H,25,26)/b8-6+/t15-,16+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50156547
(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C21H29NO4/c1-2-3-4-5-19(23)12-10-18-11-13-20(24)22(18)15-14-16-6-8-17(9-7-16)21(25)26/h6-10,12,18-19,23H,2-5,11,13-15H2,1H3,(H,25,26)/b12-10+/t18-,19-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50366137
(CHEMBL1957436)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc(Cl)cc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C26H25ClN2O4S2/c27-20-6-4-18(5-7-20)19-3-1-2-17(14-19)15-22(30)10-8-21-9-11-24(31)29(21)12-13-34-26-28-23(16-35-26)25(32)33/h1-8,10,14,16,21-22,30H,9,11-13,15H2,(H,32,33)/b10-8+/t21-,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50360621
(CHEMBL1933717)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSCCCC(O)=O)c1 |r| Show InChI InChI=1S/C21H29NO4S/c1-16-4-2-5-17(14-16)15-19(23)9-7-18-8-10-20(24)22(18)11-13-27-12-3-6-21(25)26/h2,4-5,7,9,14,18-19,23H,3,6,8,10-13,15H2,1H3,(H,25,26)/b9-7+/t18-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50156554
(4-(2-((R)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxopyrro...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSCCCC(O)=O |r| Show InChI InChI=1S/C18H31NO4S/c1-2-3-4-6-16(20)10-8-15-9-11-17(21)19(15)12-14-24-13-5-7-18(22)23/h8,10,15-16,20H,2-7,9,11-14H2,1H3,(H,22,23)/b10-8+/t15-,16-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50360628
(CHEMBL1933724)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C18H26N2O4S2/c1-2-3-4-5-14(21)8-6-13-7-9-16(22)20(13)10-11-25-18-19-15(12-26-18)17(23)24/h6,8,12-14,21H,2-5,7,9-11H2,1H3,(H,23,24)/b8-6+/t13-,14-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50366136
(CHEMBL1957435)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccccc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C26H26N2O4S2/c29-22(16-18-5-4-8-20(15-18)19-6-2-1-3-7-19)11-9-21-10-12-24(30)28(21)13-14-33-26-27-23(17-34-26)25(31)32/h1-9,11,15,17,21-22,29H,10,12-14,16H2,(H,31,32)/b11-9+/t21-,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM35847
((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM35847
((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50360627
(CHEMBL1933723)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2ncc(s2)C(O)=O)c1 |r| Show InChI InChI=1S/C21H24N2O4S2/c1-14-3-2-4-15(11-14)12-17(24)7-5-16-6-8-19(25)23(16)9-10-28-21-22-13-18(29-21)20(26)27/h2-5,7,11,13,16-17,24H,6,8-10,12H2,1H3,(H,26,27)/b7-5+/t16-,17+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM35847
((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50366139
(CHEMBL1957308)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1CCSCCCC(O)=O |r| Show InChI InChI=1S/C20H26ClNO4S/c21-16-4-1-3-15(13-16)14-18(23)8-6-17-7-9-19(24)22(17)10-12-27-11-2-5-20(25)26/h1,3-4,6,8,13,17-18,23H,2,5,7,9-12,14H2,(H,25,26)/b8-6+/t17-,18+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50142481
(7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrr...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C19H33NO4/c1-2-3-6-9-17(21)13-11-16-12-14-18(22)20(16)15-8-5-4-7-10-19(23)24/h11,13,16-17,21H,2-10,12,14-15H2,1H3,(H,23,24)/b13-11+/t16-,17-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 9.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50360626
(CHEMBL1933722)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2nc(cs2)C(O)=O)c1 |r| Show InChI InChI=1S/C21H24N2O4S2/c1-14-3-2-4-15(11-14)12-17(24)7-5-16-6-8-19(25)23(16)9-10-28-21-22-18(13-29-21)20(26)27/h2-5,7,11,13,16-17,24H,6,8-10,12H2,1H3,(H,26,27)/b7-5+/t16-,17+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 9.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50360625
(CHEMBL1933721)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCCc2nc(cs2)C(O)=O)c1 |r| Show InChI InChI=1S/C22H26N2O4S/c1-15-4-2-5-16(12-15)13-18(25)9-7-17-8-10-21(26)24(17)11-3-6-20-23-19(14-29-20)22(27)28/h2,4-5,7,9,12,14,17-18,25H,3,6,8,10-11,13H2,1H3,(H,27,28)/b9-7+/t17-,18+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50360628
(CHEMBL1933724)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C18H26N2O4S2/c1-2-3-4-5-14(21)8-6-13-7-9-16(22)20(13)10-11-25-18-19-15(12-26-18)17(23)24/h6,8,12-14,21H,2-5,7,9-11H2,1H3,(H,23,24)/b8-6+/t13-,14-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50360629
(CHEMBL1933725)Show SMILES O[C@@H](Cc1ccccc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H22N2O4S2/c23-16(12-14-4-2-1-3-5-14)8-6-15-7-9-18(24)22(15)10-11-27-20-21-17(13-28-20)19(25)26/h1-6,8,13,15-16,23H,7,9-12H2,(H,25,26)/b8-6+/t15-,16+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50366138
(CHEMBL1957437)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc2ccccc2c1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C30H28N2O4S2/c33-26(17-20-4-3-7-22(16-20)24-9-8-21-5-1-2-6-23(21)18-24)12-10-25-11-13-28(34)32(25)14-15-37-30-31-27(19-38-30)29(35)36/h1-10,12,16,18-19,25-26,33H,11,13-15,17H2,(H,35,36)/b12-10+/t25-,26+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM35847
((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50156554
(4-(2-((R)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxopyrro...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSCCCC(O)=O |r| Show InChI InChI=1S/C18H31NO4S/c1-2-3-4-6-16(20)10-8-15-9-11-17(21)19(15)12-14-24-13-5-7-18(22)23/h8,10,15-16,20H,2-7,9,11-14H2,1H3,(H,22,23)/b10-8+/t15-,16-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50360624
(CHEMBL1933720)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCCc2nc(co2)C(O)=O)c1 |r| Show InChI InChI=1S/C22H26N2O5/c1-15-4-2-5-16(12-15)13-18(25)9-7-17-8-10-21(26)24(17)11-3-6-20-23-19(14-29-20)22(27)28/h2,4-5,7,9,12,14,17-18,25H,3,6,8,10-11,13H2,1H3,(H,27,28)/b9-7+/t17-,18+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50142481
(7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrr...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C19H33NO4/c1-2-3-6-9-17(21)13-11-16-12-14-18(22)20(16)15-8-5-4-7-10-19(23)24/h11,13,16-17,21H,2-10,12,14-15H2,1H3,(H,23,24)/b13-11+/t16-,17-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50366144
(CHEMBL1957433)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1CCc1cccc(CC(O)=O)c1 |r| Show InChI InChI=1S/C24H26ClNO4/c25-20-6-2-5-19(14-20)15-22(27)9-7-21-8-10-23(28)26(21)12-11-17-3-1-4-18(13-17)16-24(29)30/h1-7,9,13-14,21-22,27H,8,10-12,15-16H2,(H,29,30)/b9-7+/t21-,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50366141
(CHEMBL1957432)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2Cc2cccc(CC(O)=O)c2)c1 |r| Show InChI InChI=1S/C24H27NO4/c1-17-4-2-5-18(12-17)14-22(26)10-8-21-9-11-23(27)25(21)16-20-7-3-6-19(13-20)15-24(28)29/h2-8,10,12-13,21-22,26H,9,11,14-16H2,1H3,(H,28,29)/b10-8+/t21-,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 78 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50360625
(CHEMBL1933721)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCCc2nc(cs2)C(O)=O)c1 |r| Show InChI InChI=1S/C22H26N2O4S/c1-15-4-2-5-16(12-15)13-18(25)9-7-17-8-10-21(26)24(17)11-3-6-20-23-19(14-29-20)22(27)28/h2,4-5,7,9,12,14,17-18,25H,3,6,8,10-11,13H2,1H3,(H,27,28)/b9-7+/t17-,18+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 84 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50156547
(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C21H29NO4/c1-2-3-4-5-19(23)12-10-18-11-13-20(24)22(18)15-14-16-6-8-17(9-7-16)21(25)26/h6-10,12,18-19,23H,2-5,11,13-15H2,1H3,(H,25,26)/b12-10+/t18-,19-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50366143
(CHEMBL1957430)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2ccc(s2)C(O)=O)c1 |r| Show InChI InChI=1S/C22H25NO4S2/c1-15-3-2-4-16(13-15)14-18(24)7-5-17-6-9-20(25)23(17)11-12-28-21-10-8-19(29-21)22(26)27/h2-5,7-8,10,13,17-18,24H,6,9,11-12,14H2,1H3,(H,26,27)/b7-5+/t17-,18+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 91 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50360623
(CHEMBL1933719)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCCc2ccc(s2)C(O)=O)c1 |r| Show InChI InChI=1S/C23H27NO4S/c1-16-4-2-5-17(14-16)15-19(25)9-7-18-8-12-22(26)24(18)13-3-6-20-10-11-21(29-20)23(27)28/h2,4-5,7,9-11,14,18-19,25H,3,6,8,12-13,15H2,1H3,(H,27,28)/b9-7+/t18-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 127 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50366142
(CHEMBL1957434)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(s1)C(O)=O |r| Show InChI InChI=1S/C22H24ClNO4S/c23-16-4-1-3-15(13-16)14-18(25)8-6-17-7-11-21(26)24(17)12-2-5-19-9-10-20(29-19)22(27)28/h1,3-4,6,8-10,13,17-18,25H,2,5,7,11-12,14H2,(H,27,28)/b8-6+/t17-,18+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50360624
(CHEMBL1933720)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCCc2nc(co2)C(O)=O)c1 |r| Show InChI InChI=1S/C22H26N2O5/c1-15-4-2-5-16(12-15)13-18(25)9-7-17-8-10-21(26)24(17)11-3-6-20-23-19(14-29-20)22(27)28/h2,4-5,7,9,12,14,17-18,25H,3,6,8,10-11,13H2,1H3,(H,27,28)/b9-7+/t17-,18+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50360627
(CHEMBL1933723)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2ncc(s2)C(O)=O)c1 |r| Show InChI InChI=1S/C21H24N2O4S2/c1-14-3-2-4-15(11-14)12-17(24)7-5-16-6-8-19(25)23(16)9-10-28-21-22-13-18(29-21)20(26)27/h2-5,7,11,13,16-17,24H,6,8-10,12H2,1H3,(H,26,27)/b7-5+/t16-,17+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50156547
(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C21H29NO4/c1-2-3-4-5-19(23)12-10-18-11-13-20(24)22(18)15-14-16-6-8-17(9-7-16)21(25)26/h6-10,12,18-19,23H,2-5,11,13-15H2,1H3,(H,25,26)/b12-10+/t18-,19-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50366142
(CHEMBL1957434)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(s1)C(O)=O |r| Show InChI InChI=1S/C22H24ClNO4S/c23-16-4-1-3-15(13-16)14-18(25)8-6-17-7-11-21(26)24(17)12-2-5-19-9-10-20(29-19)22(27)28/h1,3-4,6,8-10,13,17-18,25H,2,5,7,11-12,14H2,(H,27,28)/b8-6+/t17-,18+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50360622
(CHEMBL1933718)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCc2ccc(cc2)C(O)=O)c1 |r| Show InChI InChI=1S/C24H27NO4/c1-17-3-2-4-19(15-17)16-22(26)11-9-21-10-12-23(27)25(21)14-13-18-5-7-20(8-6-18)24(28)29/h2-9,11,15,21-22,26H,10,12-14,16H2,1H3,(H,28,29)/b11-9+/t21-,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50360626
(CHEMBL1933722)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2nc(cs2)C(O)=O)c1 |r| Show InChI InChI=1S/C21H24N2O4S2/c1-14-3-2-4-15(11-14)12-17(24)7-5-16-6-8-19(25)23(16)9-10-28-21-22-18(13-29-21)20(26)27/h2-5,7,11,13,16-17,24H,6,8-10,12H2,1H3,(H,26,27)/b7-5+/t16-,17+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50366143
(CHEMBL1957430)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2ccc(s2)C(O)=O)c1 |r| Show InChI InChI=1S/C22H25NO4S2/c1-15-3-2-4-16(13-15)14-18(24)7-5-17-6-9-20(25)23(17)11-12-28-21-10-8-19(29-21)22(26)27/h2-5,7-8,10,13,17-18,24H,6,9,11-12,14H2,1H3,(H,26,27)/b7-5+/t17-,18+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 570 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50360629
(CHEMBL1933725)Show SMILES O[C@@H](Cc1ccccc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H22N2O4S2/c23-16(12-14-4-2-1-3-5-14)8-6-15-7-9-18(24)22(15)10-11-27-20-21-17(13-28-20)19(25)26/h1-6,8,13,15-16,23H,7,9-12H2,(H,25,26)/b8-6+/t15-,16+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 770 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50360623
(CHEMBL1933719)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCCc2ccc(s2)C(O)=O)c1 |r| Show InChI InChI=1S/C23H27NO4S/c1-16-4-2-5-17(14-16)15-19(25)9-7-18-8-12-22(26)24(18)13-3-6-20-10-11-21(29-20)23(27)28/h2,4-5,7,9-11,14,18-19,25H,3,6,8,12-13,15H2,1H3,(H,27,28)/b9-7+/t18-,19+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50156554
(4-(2-((R)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxopyrro...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSCCCC(O)=O |r| Show InChI InChI=1S/C18H31NO4S/c1-2-3-4-6-16(20)10-8-15-9-11-17(21)19(15)12-14-24-13-5-7-18(22)23/h8,10,15-16,20H,2-7,9,11-14H2,1H3,(H,22,23)/b10-8+/t15-,16-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Mus musculus (Mouse)) | BDBM50366140
(CHEMBL1957431)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1c1cccc(CCC(O)=O)c1 |r| Show InChI InChI=1S/C23H24ClNO4/c24-18-5-1-4-17(13-18)15-21(26)10-8-19-9-11-22(27)25(19)20-6-2-3-16(14-20)7-12-23(28)29/h1-6,8,10,13-14,19,21,26H,7,9,11-12,15H2,(H,28,29)/b10-8+/t19-,21+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50360628
(CHEMBL1933724)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C18H26N2O4S2/c1-2-3-4-5-14(21)8-6-13-7-9-16(22)20(13)10-11-25-18-19-15(12-26-18)17(23)24/h6,8,12-14,21H,2-5,7,9-11H2,1H3,(H,23,24)/b8-6+/t13-,14-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50366136
(CHEMBL1957435)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccccc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C26H26N2O4S2/c29-22(16-18-5-4-8-20(15-18)19-6-2-1-3-7-19)11-9-21-10-12-24(30)28(21)13-14-33-26-27-23(17-34-26)25(31)32/h1-9,11,15,17,21-22,29H,10,12-14,16H2,(H,31,32)/b11-9+/t21-,22+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50366136
(CHEMBL1957435)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccccc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C26H26N2O4S2/c29-22(16-18-5-4-8-20(15-18)19-6-2-1-3-7-19)11-9-21-10-12-24(30)28(21)13-14-33-26-27-23(17-34-26)25(31)32/h1-9,11,15,17,21-22,29H,10,12-14,16H2,(H,31,32)/b11-9+/t21-,22+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50366144
(CHEMBL1957433)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1CCc1cccc(CC(O)=O)c1 |r| Show InChI InChI=1S/C24H26ClNO4/c25-20-6-2-5-19(14-20)15-22(27)9-7-21-8-10-23(28)26(21)12-11-17-3-1-4-18(13-17)16-24(29)30/h1-7,9,13-14,21-22,27H,8,10-12,15-16H2,(H,29,30)/b9-7+/t21-,22+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50360621
(CHEMBL1933717)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSCCCC(O)=O)c1 |r| Show InChI InChI=1S/C21H29NO4S/c1-16-4-2-5-17(14-16)15-19(23)9-7-18-8-10-20(24)22(18)11-13-27-12-3-6-21(25)26/h2,4-5,7,9,14,18-19,23H,3,6,8,10-13,15H2,1H3,(H,25,26)/b9-7+/t18-,19+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50366140
(CHEMBL1957431)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1c1cccc(CCC(O)=O)c1 |r| Show InChI InChI=1S/C23H24ClNO4/c24-18-5-1-4-17(13-18)15-21(26)10-8-19-9-11-22(27)25(19)20-6-2-3-16(14-20)7-12-23(28)29/h1-6,8,10,13-14,19,21,26H,7,9,11-12,15H2,(H,28,29)/b10-8+/t19-,21+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50366137
(CHEMBL1957436)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc(Cl)cc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C26H25ClN2O4S2/c27-20-6-4-18(5-7-20)19-3-1-2-17(14-19)15-22(30)10-8-21-9-11-24(31)29(21)12-13-34-26-28-23(16-35-26)25(32)33/h1-8,10,14,16,21-22,30H,9,11-13,15H2,(H,32,33)/b10-8+/t21-,22+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50366139
(CHEMBL1957308)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1CCSCCCC(O)=O |r| Show InChI InChI=1S/C20H26ClNO4S/c21-16-4-1-3-15(13-16)14-18(23)8-6-17-7-9-19(24)22(17)10-12-27-11-2-5-20(25)26/h1,3-4,6,8,13,17-18,23H,2,5,7,9-12,14H2,(H,25,26)/b8-6+/t17-,18+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50360622
(CHEMBL1933718)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCc2ccc(cc2)C(O)=O)c1 |r| Show InChI InChI=1S/C24H27NO4/c1-17-3-2-4-19(15-17)16-22(26)11-9-21-10-12-23(27)25(21)14-13-18-5-7-20(8-6-18)24(28)29/h2-9,11,15,21-22,26H,10,12-14,16H2,1H3,(H,28,29)/b11-9+/t21-,22+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50366143
(CHEMBL1957430)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2ccc(s2)C(O)=O)c1 |r| Show InChI InChI=1S/C22H25NO4S2/c1-15-3-2-4-16(13-15)14-18(24)7-5-17-6-9-20(25)23(17)11-12-28-21-10-8-19(29-21)22(26)27/h2-5,7-8,10,13,17-18,24H,6,9,11-12,14H2,1H3,(H,26,27)/b7-5+/t17-,18+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50366138
(CHEMBL1957437)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc2ccccc2c1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C30H28N2O4S2/c33-26(17-20-4-3-7-22(16-20)24-9-8-21-5-1-2-6-23(21)18-24)12-10-25-11-13-28(34)32(25)14-15-37-30-31-27(19-38-30)29(35)36/h1-10,12,16,18-19,25-26,33H,11,13-15,17H2,(H,35,36)/b12-10+/t25-,26+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50366137
(CHEMBL1957436)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc(Cl)cc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C26H25ClN2O4S2/c27-20-6-4-18(5-7-20)19-3-1-2-17(14-19)15-22(30)10-8-21-9-11-24(31)29(21)12-13-34-26-28-23(16-35-26)25(32)33/h1-8,10,14,16,21-22,30H,9,11-13,15H2,(H,32,33)/b10-8+/t21-,22+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50156554
(4-(2-((R)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxopyrro...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSCCCC(O)=O |r| Show InChI InChI=1S/C18H31NO4S/c1-2-3-4-6-16(20)10-8-15-9-11-17(21)19(15)12-14-24-13-5-7-18(22)23/h8,10,15-16,20H,2-7,9,11-14H2,1H3,(H,22,23)/b10-8+/t15-,16-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50366140
(CHEMBL1957431)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1c1cccc(CCC(O)=O)c1 |r| Show InChI InChI=1S/C23H24ClNO4/c24-18-5-1-4-17(13-18)15-21(26)10-8-19-9-11-22(27)25(19)20-6-2-3-16(14-20)7-12-23(28)29/h1-6,8,10,13-14,19,21,26H,7,9,11-12,15H2,(H,28,29)/b10-8+/t19-,21+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50360629
(CHEMBL1933725)Show SMILES O[C@@H](Cc1ccccc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H22N2O4S2/c23-16(12-14-4-2-1-3-5-14)8-6-15-7-9-18(24)22(15)10-11-27-20-21-17(13-28-20)19(25)26/h1-6,8,13,15-16,23H,7,9-12H2,(H,25,26)/b8-6+/t15-,16+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50366142
(CHEMBL1957434)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(s1)C(O)=O |r| Show InChI InChI=1S/C22H24ClNO4S/c23-16-4-1-3-15(13-16)14-18(25)8-6-17-7-11-21(26)24(17)12-2-5-19-9-10-20(29-19)22(27)28/h1,3-4,6,8-10,13,17-18,25H,2,5,7,11-12,14H2,(H,27,28)/b8-6+/t17-,18+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50360623
(CHEMBL1933719)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCCc2ccc(s2)C(O)=O)c1 |r| Show InChI InChI=1S/C23H27NO4S/c1-16-4-2-5-17(14-16)15-19(25)9-7-18-8-12-22(26)24(18)13-3-6-20-10-11-21(29-20)23(27)28/h2,4-5,7,9-11,14,18-19,25H,3,6,8,12-13,15H2,1H3,(H,27,28)/b9-7+/t18-,19+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50360626
(CHEMBL1933722)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2nc(cs2)C(O)=O)c1 |r| Show InChI InChI=1S/C21H24N2O4S2/c1-14-3-2-4-15(11-14)12-17(24)7-5-16-6-8-19(25)23(16)9-10-28-21-22-18(13-29-21)20(26)27/h2-5,7,11,13,16-17,24H,6,8-10,12H2,1H3,(H,26,27)/b7-5+/t16-,17+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50142481
(7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrr...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C19H33NO4/c1-2-3-6-9-17(21)13-11-16-12-14-18(22)20(16)15-8-5-4-7-10-19(23)24/h11,13,16-17,21H,2-10,12,14-15H2,1H3,(H,23,24)/b13-11+/t16-,17-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50366141
(CHEMBL1957432)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2Cc2cccc(CC(O)=O)c2)c1 |r| Show InChI InChI=1S/C24H27NO4/c1-17-4-2-5-18(12-17)14-22(26)10-8-21-9-11-23(27)25(21)16-20-7-3-6-19(13-20)15-24(28)29/h2-8,10,12-13,21-22,26H,9,11,14-16H2,1H3,(H,28,29)/b10-8+/t21-,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50366144
(CHEMBL1957433)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1CCc1cccc(CC(O)=O)c1 |r| Show InChI InChI=1S/C24H26ClNO4/c25-20-6-2-5-19(14-20)15-22(27)9-7-21-8-10-23(28)26(21)12-11-17-3-1-4-18(13-17)16-24(29)30/h1-7,9,13-14,21-22,27H,8,10-12,15-16H2,(H,29,30)/b9-7+/t21-,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50366139
(CHEMBL1957308)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1CCSCCCC(O)=O |r| Show InChI InChI=1S/C20H26ClNO4S/c21-16-4-1-3-15(13-16)14-18(23)8-6-17-7-9-19(24)22(17)10-12-27-11-2-5-20(25)26/h1,3-4,6,8,13,17-18,23H,2,5,7,9-12,14H2,(H,25,26)/b8-6+/t17-,18+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50360625
(CHEMBL1933721)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCCc2nc(cs2)C(O)=O)c1 |r| Show InChI InChI=1S/C22H26N2O4S/c1-15-4-2-5-16(12-15)13-18(25)9-7-17-8-10-21(26)24(17)11-3-6-20-23-19(14-29-20)22(27)28/h2,4-5,7,9,12,14,17-18,25H,3,6,8,10-11,13H2,1H3,(H,27,28)/b9-7+/t17-,18+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50366138
(CHEMBL1957437)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc2ccccc2c1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C30H28N2O4S2/c33-26(17-20-4-3-7-22(16-20)24-9-8-21-5-1-2-6-23(21)18-24)12-10-25-11-13-28(34)32(25)14-15-37-30-31-27(19-38-30)29(35)36/h1-10,12,16,18-19,25-26,33H,11,13-15,17H2,(H,35,36)/b12-10+/t25-,26+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50366141
(CHEMBL1957432)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2Cc2cccc(CC(O)=O)c2)c1 |r| Show InChI InChI=1S/C24H27NO4/c1-17-4-2-5-18(12-17)14-22(26)10-8-21-9-11-23(27)25(21)16-20-7-3-6-19(13-20)15-24(28)29/h2-8,10,12-13,21-22,26H,9,11,14-16H2,1H3,(H,28,29)/b10-8+/t21-,22+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50360624
(CHEMBL1933720)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCCc2nc(co2)C(O)=O)c1 |r| Show InChI InChI=1S/C22H26N2O5/c1-15-4-2-5-16(12-15)13-18(25)9-7-17-8-10-21(26)24(17)11-3-6-20-23-19(14-29-20)22(27)28/h2,4-5,7,9,12,14,17-18,25H,3,6,8,10-11,13H2,1H3,(H,27,28)/b9-7+/t17-,18+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50142481
(7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrr...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C19H33NO4/c1-2-3-6-9-17(21)13-11-16-12-14-18(22)20(16)15-8-5-4-7-10-19(23)24/h11,13,16-17,21H,2-10,12,14-15H2,1H3,(H,23,24)/b13-11+/t16-,17-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50360625
(CHEMBL1933721)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCCc2nc(cs2)C(O)=O)c1 |r| Show InChI InChI=1S/C22H26N2O4S/c1-15-4-2-5-16(12-15)13-18(25)9-7-17-8-10-21(26)24(17)11-3-6-20-23-19(14-29-20)22(27)28/h2,4-5,7,9,12,14,17-18,25H,3,6,8,10-11,13H2,1H3,(H,27,28)/b9-7+/t17-,18+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50360627
(CHEMBL1933723)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2ncc(s2)C(O)=O)c1 |r| Show InChI InChI=1S/C21H24N2O4S2/c1-14-3-2-4-15(11-14)12-17(24)7-5-16-6-8-19(25)23(16)9-10-28-21-22-13-18(29-21)20(26)27/h2-5,7,11,13,16-17,24H,6,8-10,12H2,1H3,(H,26,27)/b7-5+/t16-,17+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50360622
(CHEMBL1933718)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCc2ccc(cc2)C(O)=O)c1 |r| Show InChI InChI=1S/C24H27NO4/c1-17-3-2-4-19(15-17)16-22(26)11-9-21-10-12-23(27)25(21)14-13-18-5-7-20(8-6-18)24(28)29/h2-9,11,15,21-22,26H,10,12-14,16H2,1H3,(H,28,29)/b11-9+/t21-,22+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50366139
(CHEMBL1957308)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1CCSCCCC(O)=O |r| Show InChI InChI=1S/C20H26ClNO4S/c21-16-4-1-3-15(13-16)14-18(23)8-6-17-7-9-19(24)22(17)10-12-27-11-2-5-20(25)26/h1,3-4,6,8,13,17-18,23H,2,5,7,9-12,14H2,(H,25,26)/b8-6+/t17-,18+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50366144
(CHEMBL1957433)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1CCc1cccc(CC(O)=O)c1 |r| Show InChI InChI=1S/C24H26ClNO4/c25-20-6-2-5-19(14-20)15-22(27)9-7-21-8-10-23(28)26(21)12-11-17-3-1-4-18(13-17)16-24(29)30/h1-7,9,13-14,21-22,27H,8,10-12,15-16H2,(H,29,30)/b9-7+/t21-,22+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50366140
(CHEMBL1957431)Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)N1c1cccc(CCC(O)=O)c1 |r| Show InChI InChI=1S/C23H24ClNO4/c24-18-5-1-4-17(13-18)15-21(26)10-8-19-9-11-22(27)25(19)20-6-2-3-16(14-20)7-12-23(28)29/h1-6,8,10,13-14,19,21,26H,7,9,11-12,15H2,(H,28,29)/b10-8+/t19-,21+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50366141
(CHEMBL1957432)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2Cc2cccc(CC(O)=O)c2)c1 |r| Show InChI InChI=1S/C24H27NO4/c1-17-4-2-5-18(12-17)14-22(26)10-8-21-9-11-23(27)25(21)16-20-7-3-6-19(13-20)15-24(28)29/h2-8,10,12-13,21-22,26H,9,11,14-16H2,1H3,(H,28,29)/b10-8+/t21-,22+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Mus musculus (Mouse)) | BDBM50360627
(CHEMBL1933723)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2ncc(s2)C(O)=O)c1 |r| Show InChI InChI=1S/C21H24N2O4S2/c1-14-3-2-4-15(11-14)12-17(24)7-5-16-6-8-19(25)23(16)9-10-28-21-22-13-18(29-21)20(26)27/h2-5,7,11,13,16-17,24H,6,8-10,12H2,1H3,(H,26,27)/b7-5+/t16-,17+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50360621
(CHEMBL1933717)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSCCCC(O)=O)c1 |r| Show InChI InChI=1S/C21H29NO4S/c1-16-4-2-5-17(14-16)15-19(23)9-7-18-8-10-20(24)22(18)11-13-27-12-3-6-21(25)26/h2,4-5,7,9,14,18-19,23H,3,6,8,10-13,15H2,1H3,(H,25,26)/b9-7+/t18-,19+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50156547
(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C21H29NO4/c1-2-3-4-5-19(23)12-10-18-11-13-20(24)22(18)15-14-16-6-8-17(9-7-16)21(25)26/h6-10,12,18-19,23H,2-5,11,13-15H2,1H3,(H,25,26)/b12-10+/t18-,19-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Mus musculus (Mouse)) | BDBM50360624
(CHEMBL1933720)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCCc2nc(co2)C(O)=O)c1 |r| Show InChI InChI=1S/C22H26N2O5/c1-15-4-2-5-16(12-15)13-18(25)9-7-17-8-10-21(26)24(17)11-3-6-20-23-19(14-29-20)22(27)28/h2,4-5,7,9,12,14,17-18,25H,3,6,8,10-11,13H2,1H3,(H,27,28)/b9-7+/t17-,18+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Mus musculus (Mouse)) | BDBM50360621
(CHEMBL1933717)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSCCCC(O)=O)c1 |r| Show InChI InChI=1S/C21H29NO4S/c1-16-4-2-5-17(14-16)15-19(23)9-7-18-8-10-20(24)22(18)11-13-27-12-3-6-21(25)26/h2,4-5,7,9,14,18-19,23H,3,6,8,10-13,15H2,1H3,(H,25,26)/b9-7+/t18-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50156547
(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C21H29NO4/c1-2-3-4-5-19(23)12-10-18-11-13-20(24)22(18)15-14-16-6-8-17(9-7-16)21(25)26/h6-10,12,18-19,23H,2-5,11,13-15H2,1H3,(H,25,26)/b12-10+/t18-,19-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP2 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50156547
(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C21H29NO4/c1-2-3-4-5-19(23)12-10-18-11-13-20(24)22(18)15-14-16-6-8-17(9-7-16)21(25)26/h6-10,12,18-19,23H,2-5,11,13-15H2,1H3,(H,25,26)/b12-10+/t18-,19-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP4 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50366136
(CHEMBL1957435)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccccc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C26H26N2O4S2/c29-22(16-18-5-4-8-20(15-18)19-6-2-1-3-7-19)11-9-21-10-12-24(30)28(21)13-14-33-26-27-23(17-34-26)25(31)32/h1-9,11,15,17,21-22,29H,10,12-14,16H2,(H,31,32)/b11-9+/t21-,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 8 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP4 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM35847
((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP4 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50366138
(CHEMBL1957437)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc2ccccc2c1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C30H28N2O4S2/c33-26(17-20-4-3-7-22(16-20)24-9-8-21-5-1-2-6-23(21)18-24)12-10-25-11-13-28(34)32(25)14-15-37-30-31-27(19-38-30)29(35)36/h1-10,12,16,18-19,25-26,33H,11,13-15,17H2,(H,35,36)/b12-10+/t25-,26+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP2 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50156554
(4-(2-((R)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxopyrro...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSCCCC(O)=O |r| Show InChI InChI=1S/C18H31NO4S/c1-2-3-4-6-16(20)10-8-15-9-11-17(21)19(15)12-14-24-13-5-7-18(22)23/h8,10,15-16,20H,2-7,9,11-14H2,1H3,(H,22,23)/b10-8+/t15-,16-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP2 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50360626
(CHEMBL1933722)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2nc(cs2)C(O)=O)c1 |r| Show InChI InChI=1S/C21H24N2O4S2/c1-14-3-2-4-15(11-14)12-17(24)7-5-16-6-8-19(25)23(16)9-10-28-21-22-18(13-29-21)20(26)27/h2-5,7,11,13,16-17,24H,6,8-10,12H2,1H3,(H,26,27)/b7-5+/t16-,17+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 0.790 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP4 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50360626
(CHEMBL1933722)Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2nc(cs2)C(O)=O)c1 |r| Show InChI InChI=1S/C21H24N2O4S2/c1-14-3-2-4-15(11-14)12-17(24)7-5-16-6-8-19(25)23(16)9-10-28-21-22-18(13-29-21)20(26)27/h2-5,7,11,13,16-17,24H,6,8-10,12H2,1H3,(H,26,27)/b7-5+/t16-,17+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 90 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP2 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50366136
(CHEMBL1957435)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccccc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C26H26N2O4S2/c29-22(16-18-5-4-8-20(15-18)19-6-2-1-3-7-19)11-9-21-10-12-24(30)28(21)13-14-33-26-27-23(17-34-26)25(31)32/h1-9,11,15,17,21-22,29H,10,12-14,16H2,(H,31,32)/b11-9+/t21-,22+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP2 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50366137
(CHEMBL1957436)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc(Cl)cc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C26H25ClN2O4S2/c27-20-6-4-18(5-7-20)19-3-1-2-17(14-19)15-22(30)10-8-21-9-11-24(31)29(21)12-13-34-26-28-23(16-35-26)25(32)33/h1-8,10,14,16,21-22,30H,9,11-13,15H2,(H,32,33)/b10-8+/t21-,22+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 260 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP2 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50366138
(CHEMBL1957437)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc2ccccc2c1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C30H28N2O4S2/c33-26(17-20-4-3-7-22(16-20)24-9-8-21-5-1-2-6-23(21)18-24)12-10-25-11-13-28(34)32(25)14-15-37-30-31-27(19-38-30)29(35)36/h1-10,12,16,18-19,25-26,33H,11,13-15,17H2,(H,35,36)/b12-10+/t25-,26+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 480 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP4 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM35847
((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP2 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50156554
(4-(2-((R)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxopyrro...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSCCCC(O)=O |r| Show InChI InChI=1S/C18H31NO4S/c1-2-3-4-6-16(20)10-8-15-9-11-17(21)19(15)12-14-24-13-5-7-18(22)23/h8,10,15-16,20H,2-7,9,11-14H2,1H3,(H,22,23)/b10-8+/t15-,16-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP4 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50142481
(7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrr...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C19H33NO4/c1-2-3-6-9-17(21)13-11-16-12-14-18(22)20(16)15-8-5-4-7-10-19(23)24/h11,13,16-17,21H,2-10,12,14-15H2,1H3,(H,23,24)/b13-11+/t16-,17-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP2 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50366137
(CHEMBL1957436)Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc(Cl)cc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C26H25ClN2O4S2/c27-20-6-4-18(5-7-20)19-3-1-2-17(14-19)15-22(30)10-8-21-9-11-24(31)29(21)12-13-34-26-28-23(16-35-26)25(32)33/h1-8,10,14,16,21-22,30H,9,11-13,15H2,(H,32,33)/b10-8+/t21-,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 27 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP4 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50142481
(7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrr...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C19H33NO4/c1-2-3-6-9-17(21)13-11-16-12-14-18(22)20(16)15-8-5-4-7-10-19(23)24/h11,13,16-17,21H,2-10,12,14-15H2,1H3,(H,23,24)/b13-11+/t16-,17-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 8.40 | n/a | n/a | n/a | n/a |
Minase Research Institute
Curated by ChEMBL
| Assay Description Agonist activity at rat EP4 receptor |
Bioorg Med Chem 20: 2235-51 (2012)
Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G |
More data for this Ligand-Target Pair | |