Affinity Data by PubMed id=22483584

PubMed code 22483584

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
DNA (cytosine-5)-methyltransferase 1 (Homo sapiens (Human))	BDBM50009672 (AdoHcy \| CHEMBL418052 \| S-(5'-adenosyl)-L-homocyst...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	941	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Inhibition of human Dnmt1 using oligonucleotide 2 as substrate after 5000 sec by micro plate reader based real-time break-light assay				Bioorg Med Chem Lett 22: 3079-82 (2012) Article DOI: 10.1016/j.bmcl.2012.03.072 BindingDB Entry DOI: 10.7270/Q25Q4X4W
University of Southampton Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA (cytosine-5)-methyltransferase 1 (Homo sapiens (Human))	BDBM50381263 (CHEMBL2018855) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.32E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Inhibition of human Dnmt1 using oligonucleotide 2 as substrate after 5000 sec by micro plate reader based real-time break-light assay				Bioorg Med Chem Lett 22: 3079-82 (2012) Article DOI: 10.1016/j.bmcl.2012.03.072 BindingDB Entry DOI: 10.7270/Q25Q4X4W
University of Southampton Curated by ChEMBL					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 1 (Homo sapiens (Human))	BDBM50381264 (CHEMBL1235825) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3.02E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Inhibition of human Dnmt1 using oligonucleotide 2 as substrate after 5000 sec by micro plate reader based real-time break-light assay				Bioorg Med Chem Lett 22: 3079-82 (2012) Article DOI: 10.1016/j.bmcl.2012.03.072 BindingDB Entry DOI: 10.7270/Q25Q4X4W
University of Southampton Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%