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PubMed code 22483967

Compile data set for download or QSAR
Found 38 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381886
PNG
(CHEMBL2022363)
Show SMILES Fc1ccc(Cn2c3ccccc3cc(C(=O)NC3CCCCCC3)c2=O)cc1
Show InChI InChI=1S/C24H25FN2O2/c25-19-13-11-17(12-14-19)16-27-22-10-6-5-7-18(22)15-21(24(27)29)23(28)26-20-8-3-1-2-4-9-20/h5-7,10-15,20H,1-4,8-9,16H2,(H,26,28)
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0.25n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381882
PNG
(CHEMBL2022694)
Show SMILES Oc1c(C(=O)NC2CCCCCC2)c(=O)n(CCN2CCOCC2)c2ncccc12
Show InChI InChI=1S/C22H30N4O4/c27-19-17-8-5-9-23-20(17)26(11-10-25-12-14-30-15-13-25)22(29)18(19)21(28)24-16-6-3-1-2-4-7-16/h5,8-9,16,27H,1-4,6-7,10-15H2,(H,24,28)
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1.80n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50180036
PNG
((6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetra...)
Show SMILES CCCC(C)(C)c1ccc2[C@@H]3CC(C)=CC[C@H]3C(C)(C)Oc2c1 |r,c:13|
Show InChI InChI=1S/C22H32O/c1-7-12-21(3,4)16-9-10-17-18-13-15(2)8-11-19(18)22(5,6)23-20(17)14-16/h8-10,14,18-19H,7,11-13H2,1-6H3/t18-,19+/m0/s1
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1.82n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381885
PNG
(CHEMBL2022364)
Show SMILES O=C(NC1CCCCCC1)c1cc2ccccc2n(CCN2CCOCC2)c1=O
Show InChI InChI=1S/C23H31N3O3/c27-22(24-19-8-3-1-2-4-9-19)20-17-18-7-5-6-10-21(18)26(23(20)28)12-11-25-13-15-29-16-14-25/h5-7,10,17,19H,1-4,8-9,11-16H2,(H,24,27)
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2n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381883
PNG
(CHEMBL2022692)
Show SMILES Oc1c(C(=O)NC2CCCCC2)c(=O)n(CCN2CCOCC2)c2ncccc12
Show InChI InChI=1S/C21H28N4O4/c26-18-16-7-4-8-22-19(16)25(10-9-24-11-13-29-14-12-24)21(28)17(18)20(27)23-15-5-2-1-3-6-15/h4,7-8,15,26H,1-3,5-6,9-14H2,(H,23,27)
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2.40n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381888
PNG
(CHEMBL2022361)
Show SMILES Fc1ccc(Cn2c3ccccc3cc(C(=O)NC3CCCCC3)c2=O)cc1
Show InChI InChI=1S/C23H23FN2O2/c24-18-12-10-16(11-13-18)15-26-21-9-5-4-6-17(21)14-20(23(26)28)22(27)25-19-7-2-1-3-8-19/h4-6,9-14,19H,1-3,7-8,15H2,(H,25,27)
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2.90n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50200170
PNG
(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Show SMILES Cc1ccc(Cn2nc(cc2-c2ccc(Cl)c(C)c2)C(=O)N[C@H]2[C@@]3(C)CC[C@H](C3)C2(C)C)cc1 |r|
Show InChI InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22-,27-,29+/m1/s1
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4.35n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381880
PNG
(CHEMBL2022698)
Show SMILES Fc1ccc(Cn2cccc(C(=O)NC3CCCCCC3)c2=O)cc1
Show InChI InChI=1S/C20H23FN2O2/c21-16-11-9-15(10-12-16)14-23-13-5-8-18(20(23)25)19(24)22-17-6-3-1-2-4-7-17/h5,8-13,17H,1-4,6-7,14H2,(H,22,24)
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7.80n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381887
PNG
(CHEMBL2022362)
Show SMILES O=C(NC1CCCCC1)c1cc2ccccc2n(CCN2CCOCC2)c1=O
Show InChI InChI=1S/C22H29N3O3/c26-21(23-18-7-2-1-3-8-18)19-16-17-6-4-5-9-20(17)25(22(19)27)11-10-24-12-14-28-15-13-24/h4-6,9,16,18H,1-3,7-8,10-15H2,(H,23,26)
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9n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381886
PNG
(CHEMBL2022363)
Show SMILES Fc1ccc(Cn2c3ccccc3cc(C(=O)NC3CCCCCC3)c2=O)cc1
Show InChI InChI=1S/C24H25FN2O2/c25-19-13-11-17(12-14-19)16-27-22-10-6-5-7-18(22)15-21(24(27)29)23(28)26-20-8-3-1-2-4-9-20/h5-7,10-15,20H,1-4,8-9,16H2,(H,26,28)
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11.6n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381889
PNG
(CHEMBL2022360)
Show SMILES O=C(NC1CCCCC1)c1cc2ccccc2n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C23H24N2O2/c26-22(24-19-12-5-2-6-13-19)20-15-18-11-7-8-14-21(18)25(23(20)27)16-17-9-3-1-4-10-17/h1,3-4,7-11,14-15,19H,2,5-6,12-13,16H2,(H,24,26)
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16n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381888
PNG
(CHEMBL2022361)
Show SMILES Fc1ccc(Cn2c3ccccc3cc(C(=O)NC3CCCCC3)c2=O)cc1
Show InChI InChI=1S/C23H23FN2O2/c24-18-12-10-16(11-13-18)15-26-21-9-5-4-6-17(21)14-20(23(26)28)22(27)25-19-7-2-1-3-8-19/h4-6,9-14,19H,1-3,7-8,15H2,(H,25,27)
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16.5n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381873
PNG
(CHEMBL2022696)
Show SMILES Fc1ccc(Cn2cccc(C(=O)NC3CCCCC3)c2=O)cc1
Show InChI InChI=1S/C19H21FN2O2/c20-15-10-8-14(9-11-15)13-22-12-4-7-17(19(22)24)18(23)21-16-5-2-1-3-6-16/h4,7-12,16H,1-3,5-6,13H2,(H,21,23)
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20n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381875
PNG
(CHEMBL2022703)
Show SMILES Fc1ccc(COc2ncccc2C(=O)NC2CCCCCC2)cc1
Show InChI InChI=1S/C20H23FN2O2/c21-16-11-9-15(10-12-16)14-25-20-18(8-5-13-22-20)19(24)23-17-6-3-1-2-4-7-17/h5,8-13,17H,1-4,6-7,14H2,(H,23,24)
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25n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381880
PNG
(CHEMBL2022698)
Show SMILES Fc1ccc(Cn2cccc(C(=O)NC3CCCCCC3)c2=O)cc1
Show InChI InChI=1S/C20H23FN2O2/c21-16-11-9-15(10-12-16)14-23-13-5-8-18(20(23)25)19(24)22-17-6-3-1-2-4-7-17/h5,8-13,17H,1-4,6-7,14H2,(H,22,24)
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43n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381883
PNG
(CHEMBL2022692)
Show SMILES Oc1c(C(=O)NC2CCCCC2)c(=O)n(CCN2CCOCC2)c2ncccc12
Show InChI InChI=1S/C21H28N4O4/c26-18-16-7-4-8-22-19(16)25(10-9-24-11-13-29-14-12-24)21(28)17(18)20(27)23-15-5-2-1-3-6-15/h4,7-8,15,26H,1-3,5-6,9-14H2,(H,23,27)
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64.6n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381889
PNG
(CHEMBL2022360)
Show SMILES O=C(NC1CCCCC1)c1cc2ccccc2n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C23H24N2O2/c26-22(24-19-12-5-2-6-13-19)20-15-18-11-7-8-14-21(18)25(23(20)27)16-17-9-3-1-4-10-17/h1,3-4,7-11,14-15,19H,2,5-6,12-13,16H2,(H,24,26)
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67n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381873
PNG
(CHEMBL2022696)
Show SMILES Fc1ccc(Cn2cccc(C(=O)NC3CCCCC3)c2=O)cc1
Show InChI InChI=1S/C19H21FN2O2/c20-15-10-8-14(9-11-15)13-22-12-4-7-17(19(22)24)18(23)21-16-5-2-1-3-6-16/h4,7-12,16H,1-3,5-6,13H2,(H,21,23)
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70n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381884
PNG
(CHEMBL2022365)
Show SMILES Oc1c(C(=O)NC2CCCCC2)c(=O)n(Cc2ccccc2)c2ncccc12
Show InChI InChI=1S/C22H23N3O3/c26-19-17-12-7-13-23-20(17)25(14-15-8-3-1-4-9-15)22(28)18(19)21(27)24-16-10-5-2-6-11-16/h1,3-4,7-9,12-13,16,26H,2,5-6,10-11,14H2,(H,24,27)
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79n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381875
PNG
(CHEMBL2022703)
Show SMILES Fc1ccc(COc2ncccc2C(=O)NC2CCCCCC2)cc1
Show InChI InChI=1S/C20H23FN2O2/c21-16-11-9-15(10-12-16)14-25-20-18(8-5-13-22-20)19(24)23-17-6-3-1-2-4-7-17/h5,8-13,17H,1-4,6-7,14H2,(H,23,24)
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100n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50180036
PNG
((6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetra...)
Show SMILES CCCC(C)(C)c1ccc2[C@@H]3CC(C)=CC[C@H]3C(C)(C)Oc2c1 |r,c:13|
Show InChI InChI=1S/C22H32O/c1-7-12-21(3,4)16-9-10-17-18-13-15(2)8-11-19(18)22(5,6)23-20(17)14-16/h8-10,14,18-19H,7,11-13H2,1-6H3/t18-,19+/m0/s1
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117n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50200170
PNG
(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Show SMILES Cc1ccc(Cn2nc(cc2-c2ccc(Cl)c(C)c2)C(=O)N[C@H]2[C@@]3(C)CC[C@H](C3)C2(C)C)cc1 |r|
Show InChI InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22-,27-,29+/m1/s1
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121n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381878
PNG
(CHEMBL2022700)
Show SMILES Fc1ccc(COc2nc3ccccc3cc2C(=O)NC2CCCCC2)cc1
Show InChI InChI=1S/C23H23FN2O2/c24-18-12-10-16(11-13-18)15-28-23-20(14-17-6-4-5-9-21(17)26-23)22(27)25-19-7-2-1-3-8-19/h4-6,9-14,19H,1-3,7-8,15H2,(H,25,27)
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130n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381881
PNG
(CHEMBL2022695)
Show SMILES O=C(NC1CCCCC1)c1cccn(Cc2ccccc2)c1=O
Show InChI InChI=1S/C19H22N2O2/c22-18(20-16-10-5-2-6-11-16)17-12-7-13-21(19(17)23)14-15-8-3-1-4-9-15/h1,3-4,7-9,12-13,16H,2,5-6,10-11,14H2,(H,20,22)
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200n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381885
PNG
(CHEMBL2022364)
Show SMILES O=C(NC1CCCCCC1)c1cc2ccccc2n(CCN2CCOCC2)c1=O
Show InChI InChI=1S/C23H31N3O3/c27-22(24-19-8-3-1-2-4-9-19)20-17-18-7-5-6-10-21(18)26(23(20)28)12-11-25-13-15-29-16-14-25/h5-7,10,17,19H,1-4,8-9,11-16H2,(H,24,27)
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206n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381882
PNG
(CHEMBL2022694)
Show SMILES Oc1c(C(=O)NC2CCCCCC2)c(=O)n(CCN2CCOCC2)c2ncccc12
Show InChI InChI=1S/C22H30N4O4/c27-19-17-8-5-9-23-20(17)26(11-10-25-12-14-30-15-13-25)22(29)18(19)21(28)24-16-6-3-1-2-4-7-16/h5,8-9,16,27H,1-4,6-7,10-15H2,(H,24,28)
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234n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381876
PNG
(CHEMBL2022702)
Show SMILES Fc1ccc(COc2ncccc2C(=O)NC2CCCCC2)cc1
Show InChI InChI=1S/C19H21FN2O2/c20-15-10-8-14(9-11-15)13-24-19-17(7-4-12-21-19)18(23)22-16-5-2-1-3-6-16/h4,7-12,16H,1-3,5-6,13H2,(H,22,23)
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250n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381887
PNG
(CHEMBL2022362)
Show SMILES O=C(NC1CCCCC1)c1cc2ccccc2n(CCN2CCOCC2)c1=O
Show InChI InChI=1S/C22H29N3O3/c26-21(23-18-7-2-1-3-8-18)19-16-17-6-4-5-9-20(17)25(22(19)27)11-10-24-12-14-28-15-13-24/h4-6,9,16,18H,1-3,7-8,10-15H2,(H,23,26)
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300n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381884
PNG
(CHEMBL2022365)
Show SMILES Oc1c(C(=O)NC2CCCCC2)c(=O)n(Cc2ccccc2)c2ncccc12
Show InChI InChI=1S/C22H23N3O3/c26-19-17-12-7-13-23-20(17)25(14-15-8-3-1-4-9-15)22(28)18(19)21(27)24-16-10-5-2-6-11-16/h1,3-4,7-9,12-13,16,26H,2,5-6,10-11,14H2,(H,24,27)
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560n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381879
PNG
(CHEMBL2022699)
Show SMILES O=C(NC1CCCCCC1)c1cccn(CCN2CCOCC2)c1=O
Show InChI InChI=1S/C19H29N3O3/c23-18(20-16-6-3-1-2-4-7-16)17-8-5-9-22(19(17)24)11-10-21-12-14-25-15-13-21/h5,8-9,16H,1-4,6-7,10-15H2,(H,20,23)
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790n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381881
PNG
(CHEMBL2022695)
Show SMILES O=C(NC1CCCCC1)c1cccn(Cc2ccccc2)c1=O
Show InChI InChI=1S/C19H22N2O2/c22-18(20-16-10-5-2-6-11-16)17-12-7-13-21(19(17)23)14-15-8-3-1-4-9-15/h1,3-4,7-9,12-13,16H,2,5-6,10-11,14H2,(H,20,22)
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800n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381877
PNG
(CHEMBL2022701)
Show SMILES O=C(NC1CCCCC1)c1cccnc1OCc1ccccc1
Show InChI InChI=1S/C19H22N2O2/c22-18(21-16-10-5-2-6-11-16)17-12-7-13-20-19(17)23-14-15-8-3-1-4-9-15/h1,3-4,7-9,12-13,16H,2,5-6,10-11,14H2,(H,21,22)
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916n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381879
PNG
(CHEMBL2022699)
Show SMILES O=C(NC1CCCCCC1)c1cccn(CCN2CCOCC2)c1=O
Show InChI InChI=1S/C19H29N3O3/c23-18(20-16-6-3-1-2-4-7-16)17-8-5-9-22(19(17)24)11-10-21-12-14-25-15-13-21/h5,8-9,16H,1-4,6-7,10-15H2,(H,20,23)
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950n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381878
PNG
(CHEMBL2022700)
Show SMILES Fc1ccc(COc2nc3ccccc3cc2C(=O)NC2CCCCC2)cc1
Show InChI InChI=1S/C23H23FN2O2/c24-18-12-10-16(11-13-18)15-28-23-20(14-17-6-4-5-9-21(17)26-23)22(27)25-19-7-2-1-3-8-19/h4-6,9-14,19H,1-3,7-8,15H2,(H,25,27)
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1.20E+3n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381876
PNG
(CHEMBL2022702)
Show SMILES Fc1ccc(COc2ncccc2C(=O)NC2CCCCC2)cc1
Show InChI InChI=1S/C19H21FN2O2/c20-15-10-8-14(9-11-15)13-24-19-17(7-4-12-21-19)18(23)22-16-5-2-1-3-6-16/h4,7-12,16H,1-3,5-6,13H2,(H,22,23)
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1.81E+3n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50381874
PNG
(CHEMBL2022697)
Show SMILES O=C(NC1CCCCC1)c1cccn(CCN2CCOCC2)c1=O
Show InChI InChI=1S/C18H27N3O3/c22-17(19-15-5-2-1-3-6-15)16-7-4-8-21(18(16)23)10-9-20-11-13-24-14-12-20/h4,7-8,15H,1-3,5-6,9-14H2,(H,19,22)
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7.90E+3n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381877
PNG
(CHEMBL2022701)
Show SMILES O=C(NC1CCCCC1)c1cccnc1OCc1ccccc1
Show InChI InChI=1S/C19H22N2O2/c22-18(21-16-10-5-2-6-11-16)17-12-7-13-20-19(17)23-14-15-8-3-1-4-9-15/h1,3-4,7-9,12-13,16H,2,5-6,10-11,14H2,(H,21,22)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50381874
PNG
(CHEMBL2022697)
Show SMILES O=C(NC1CCCCC1)c1cccn(CCN2CCOCC2)c1=O
Show InChI InChI=1S/C18H27N3O3/c22-17(19-15-5-2-1-3-6-15)16-7-4-8-21(18(16)23)10-9-20-11-13-24-14-12-20/h4,7-8,15H,1-3,5-6,9-14H2,(H,19,22)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in human HEK293 cell membrane after 90 mins


Eur J Med Chem 52: 284-94 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.031
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%