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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human)) | BDBM3175 (3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.4 | 25 |
East China University of Science and Technology | Assay Description The inhibition assays against RSK2 in vitro were determined by ADP Quest® (DiscoveRx) in 96-well flat-bottom plates according to the manufacturer... | J Enzyme Inhib Med Chem 28: 747-52 (2013) Article DOI: 10.3109/14756366.2012.681651 BindingDB Entry DOI: 10.7270/Q2DV1HT9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human)) | BDBM241956 (5-(2-(4-Hydroxyphenyl)hydrazono)pyrimidine-2,4,6(1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.95E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
East China University of Science and Technology | Assay Description The inhibition assays against RSK2 in vitro were determined by ADP Quest® (DiscoveRx) in 96-well flat-bottom plates according to the manufacturer... | J Enzyme Inhib Med Chem 28: 747-52 (2013) Article DOI: 10.3109/14756366.2012.681651 BindingDB Entry DOI: 10.7270/Q2DV1HT9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human)) | BDBM241958 (5-(2-(4-Hydroxyphenyl)hydrazono)-dihydro-2-thioxop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.19E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
East China University of Science and Technology | Assay Description The inhibition assays against RSK2 in vitro were determined by ADP Quest® (DiscoveRx) in 96-well flat-bottom plates according to the manufacturer... | J Enzyme Inhib Med Chem 28: 747-52 (2013) Article DOI: 10.3109/14756366.2012.681651 BindingDB Entry DOI: 10.7270/Q2DV1HT9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human)) | BDBM241957 (5-(2-(4-Morpholinophenyl)hydrazono)pyrimidine-2,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.11E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
East China University of Science and Technology | Assay Description The inhibition assays against RSK2 in vitro were determined by ADP Quest® (DiscoveRx) in 96-well flat-bottom plates according to the manufacturer... | J Enzyme Inhib Med Chem 28: 747-52 (2013) Article DOI: 10.3109/14756366.2012.681651 BindingDB Entry DOI: 10.7270/Q2DV1HT9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human)) | BDBM241959 (5-(2-(4-Morpholinophenyl)hydrazono-dihydro-2-thiox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.23E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
East China University of Science and Technology | Assay Description The inhibition assays against RSK2 in vitro were determined by ADP Quest® (DiscoveRx) in 96-well flat-bottom plates according to the manufacturer... | J Enzyme Inhib Med Chem 28: 747-52 (2013) Article DOI: 10.3109/14756366.2012.681651 BindingDB Entry DOI: 10.7270/Q2DV1HT9 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
