Affinity Data by PubMed id=22607683

PubMed code 22607683

Found 19 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384273 (CHEMBL2030612) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384274 (CHEMBL2030613) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384268 (CHEMBL2030607) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384265 (CHEMBL2030452) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384271 (CHEMBL2030610) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384272 (CHEMBL2030611) Show SMILES CC(C)c1nc(SCc2cc(C)ccc2C)[nH]c(=O)c1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384269 (CHEMBL2030608) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384270 (CHEMBL2030609) Show SMILES O=c1[nH]c(SCc2ccccc2)nc(C2CCCCC2)c1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384267 (CHEMBL2030606) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384264 (CHEMBL316966) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384275 (CHEMBL2030614) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.27E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384278 (CHEMBL2030617) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384263 (CHEMBL2030618) Show SMILES OC(=O)CSc1nc(C2CCCCC2)c(C#N)c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384266 (CHEMBL2030605) Show SMILES O=c1[nH]c(=S)[nH]c(C2CCCCC2)c1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384279 (CHEMBL2030620) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384277 (CHEMBL2030616) Show SMILES O=c1[nH]c(Nc2ccccc2)nc(C2CCCCC2)c1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384281 (CHEMBL2030619) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384276 (CHEMBL2030615) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50384280 (CHEMBL2030621) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis				Bioorg Med Chem Lett 22: 4038-43 (2012) Article DOI: 10.1016/j.bmcl.2012.04.082 BindingDB Entry DOI: 10.7270/Q2H70GVP
University of Texas Medical Branch Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%