Affinity Data by PubMed id=22682300

PubMed code 22682300

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50393706 (CHEMBL2158999) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of norA-mediated ethidium bromide efflux in methicillin-resistant Staphylococcus aureus SA-1199B by spectrofluorometric analysis				Bioorg Med Chem 20: 4514-21 (2012) Article DOI: 10.1016/j.bmc.2012.05.025 BindingDB Entry DOI: 10.7270/Q2K075D0
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50017712 ((-)-reserpine \| (3beta,16beta,17alpha,18beta,20alp...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of norA-mediated ethidium bromide efflux in methicillin-resistant Staphylococcus aureus SA-1199B by spectrofluorometric analysis				Bioorg Med Chem 20: 4514-21 (2012) Article DOI: 10.1016/j.bmc.2012.05.025 BindingDB Entry DOI: 10.7270/Q2K075D0
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50393707 (CHEMBL2158998) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of norA-mediated ethidium bromide efflux in methicillin-resistant Staphylococcus aureus SA-1199B by spectrofluorometric analysis				Bioorg Med Chem 20: 4514-21 (2012) Article DOI: 10.1016/j.bmc.2012.05.025 BindingDB Entry DOI: 10.7270/Q2K075D0
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50393711 (CHEMBL358518) Show SMILES COc1cc(O)cc(C)c1\C=C\C(=O)c1ccc(O)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of norA-mediated ethidium bromide efflux in methicillin-resistant Staphylococcus aureus SA-1199B by spectrofluorometric analysis				Bioorg Med Chem 20: 4514-21 (2012) Article DOI: 10.1016/j.bmc.2012.05.025 BindingDB Entry DOI: 10.7270/Q2K075D0
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50393710 (CHEMBL422481) Show SMILES COc1ccc(OC)c(\C=C\C(=O)c2ccc(O)cc2)c1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of norA-mediated ethidium bromide efflux in methicillin-resistant Staphylococcus aureus SA-1199B by spectrofluorometric analysis				Bioorg Med Chem 20: 4514-21 (2012) Article DOI: 10.1016/j.bmc.2012.05.025 BindingDB Entry DOI: 10.7270/Q2K075D0
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50393709 (CHEMBL2158996) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of norA-mediated ethidium bromide efflux in methicillin-resistant Staphylococcus aureus SA-1199B by spectrofluorometric analysis				Bioorg Med Chem 20: 4514-21 (2012) Article DOI: 10.1016/j.bmc.2012.05.025 BindingDB Entry DOI: 10.7270/Q2K075D0
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50393708 (CHEMBL2158997) Show SMILES CN(C)CCOc1ccc(cc1)C(=O)\C=C\c1ccccc1F Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of norA-mediated ethidium bromide efflux in methicillin-resistant Staphylococcus aureus SA-1199B by spectrofluorometric analysis				Bioorg Med Chem 20: 4514-21 (2012) Article DOI: 10.1016/j.bmc.2012.05.025 BindingDB Entry DOI: 10.7270/Q2K075D0
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50393714 (CHEMBL142493) Show SMILES COc1cccc(\C=C\C(=O)c2ccc(O)cc2)c1OC Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of norA-mediated ethidium bromide efflux in methicillin-resistant Staphylococcus aureus SA-1199B by spectrofluorometric analysis				Bioorg Med Chem 20: 4514-21 (2012) Article DOI: 10.1016/j.bmc.2012.05.025 BindingDB Entry DOI: 10.7270/Q2K075D0
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50393713 (CHEMBL2158995) Show SMILES COc1ccc(\C=C\C(=O)c2ccc(O)cc2)cc1OC Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of norA-mediated ethidium bromide efflux in methicillin-resistant Staphylococcus aureus SA-1199B by spectrofluorometric analysis				Bioorg Med Chem 20: 4514-21 (2012) Article DOI: 10.1016/j.bmc.2012.05.025 BindingDB Entry DOI: 10.7270/Q2K075D0
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50393715 (CHEMBL2158994) Show SMILES CN(C)CCOc1ccc(cc1)C(=O)\C=C\c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of norA-mediated ethidium bromide efflux in methicillin-resistant Staphylococcus aureus SA-1199B by spectrofluorometric analysis				Bioorg Med Chem 20: 4514-21 (2012) Article DOI: 10.1016/j.bmc.2012.05.025 BindingDB Entry DOI: 10.7270/Q2K075D0
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50393712 (CHEMBL434066) Show SMILES COc1ccc(\C=C\C(=O)c2ccc(O)cc2)c(OC)c1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of norA-mediated ethidium bromide efflux in methicillin-resistant Staphylococcus aureus SA-1199B by spectrofluorometric analysis				Bioorg Med Chem 20: 4514-21 (2012) Article DOI: 10.1016/j.bmc.2012.05.025 BindingDB Entry DOI: 10.7270/Q2K075D0
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%