Affinity Data by PubMed id=22703703

PubMed code 22703703

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50086170 ((4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-di...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	10.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Porto Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by liquid scintillation counting				Eur J Med Chem 54: 914-8 (2012) Article DOI: 10.1016/j.ejmech.2012.05.033 BindingDB Entry DOI: 10.7270/Q2S46T0B
Universidade do Porto Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50350114 (CHEMBL1814066) Show SMILES Oc1ccc(NC(=O)c2coc3ccccc3c2=O)cc1O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Porto Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by liquid scintillation counting				Eur J Med Chem 54: 914-8 (2012) Article DOI: 10.1016/j.ejmech.2012.05.033 BindingDB Entry DOI: 10.7270/Q2S46T0B
Universidade do Porto Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50350111 (CHEMBL1814064) Show SMILES Oc1ccc(NC(=O)c2coc3ccccc3c2=O)cc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Porto Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by liquid scintillation counting				Eur J Med Chem 54: 914-8 (2012) Article DOI: 10.1016/j.ejmech.2012.05.033 BindingDB Entry DOI: 10.7270/Q2S46T0B
Universidade do Porto Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50350112 (CHEMBL1814065) Show SMILES COc1ccc(NC(=O)c2coc3ccccc3c2=O)cc1O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Porto Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by liquid scintillation counting				Eur J Med Chem 54: 914-8 (2012) Article DOI: 10.1016/j.ejmech.2012.05.033 BindingDB Entry DOI: 10.7270/Q2S46T0B
Universidade do Porto Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50350118 (CHEMBL1814067) Show SMILES COc1ccc(NC(=O)c2coc3ccccc3c2=O)cc1OC Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Porto Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by liquid scintillation counting				Eur J Med Chem 54: 914-8 (2012) Article DOI: 10.1016/j.ejmech.2012.05.033 BindingDB Entry DOI: 10.7270/Q2S46T0B
Universidade do Porto Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50333651 (4-oxo-N-phenyl-4H-chromene-3-carboxamide \| CHEMBL1...) Show SMILES O=C(Nc1ccccc1)c1coc2ccccc2c1=O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Porto Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by liquid scintillation counting				Eur J Med Chem 54: 914-8 (2012) Article DOI: 10.1016/j.ejmech.2012.05.033 BindingDB Entry DOI: 10.7270/Q2S46T0B
Universidade do Porto Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%