Affinity Data by PubMed id=22712432

PubMed code 22712432

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50396234 (CHEMBL2172214 \| US9402842, 57) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>4.14E+4	n/a	n/a	n/a	n/a
The University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human RXRalpha expressed in african green monkey COS1 cells assessed as induction of RXRE transcriptional activity after 12 hrs b...				J Med Chem 55: 5965-81 (2012) Article DOI: 10.1021/jm3006806 BindingDB Entry DOI: 10.7270/Q2QR4Z7Z
The University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50396236 (CHEMBL2172210) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.96E+3	n/a	n/a	n/a	n/a
The University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human RXRalpha expressed in african green monkey COS1 cells assessed as induction of RXRE transcriptional activity after 12 hrs b...				J Med Chem 55: 5965-81 (2012) Article DOI: 10.1021/jm3006806 BindingDB Entry DOI: 10.7270/Q2QR4Z7Z
The University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50396235 (CHEMBL2172299) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a
The University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human RXRalpha expressed in african green monkey COS1 cells assessed as induction of RXRE transcriptional activity after 12 hrs b...				J Med Chem 55: 5965-81 (2012) Article DOI: 10.1021/jm3006806 BindingDB Entry DOI: 10.7270/Q2QR4Z7Z
The University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50396238 (CHEMBL2172212 \| US9402842, 62) Show SMILES NCCCn1c2-c3ccccc3C(=O)c2c2ccc(N)cc2c1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.37E+3	n/a	n/a	n/a	n/a
The University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human RXRalpha expressed in african green monkey COS1 cells assessed as induction of RXRE transcriptional activity after 12 hrs b...				J Med Chem 55: 5965-81 (2012) Article DOI: 10.1021/jm3006806 BindingDB Entry DOI: 10.7270/Q2QR4Z7Z
The University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50396237 (CHEMBL2172208) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.65E+3	n/a	n/a	n/a	n/a
The University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human RXRalpha expressed in african green monkey COS1 cells assessed as induction of RXRE transcriptional activity after 12 hrs b...				J Med Chem 55: 5965-81 (2012) Article DOI: 10.1021/jm3006806 BindingDB Entry DOI: 10.7270/Q2QR4Z7Z
The University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%