Affinity Data by PubMed id=22738633

PubMed code 22738633

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Hepatocyte growth factor receptor (Canis familiaris)	BDBM50341636 ((3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-MET...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of Met-triggered cell scattering in HGF-stimulated MDCK cells preincubated for overnight before HGF challenge measured after 24 to 48 hrs				Bioorg Med Chem Lett 22: 4693-6 (2012) Article DOI: 10.1016/j.bmcl.2012.05.078 BindingDB Entry DOI: 10.7270/Q2PV6MF0
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Canis familiaris)	BDBM50359982 (CHEMBL1927771) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of Met-triggered cell scattering in HGF-stimulated MDCK cells preincubated for overnight before HGF challenge measured after 24 to 48 hrs				Bioorg Med Chem Lett 22: 4693-6 (2012) Article DOI: 10.1016/j.bmcl.2012.05.078 BindingDB Entry DOI: 10.7270/Q2PV6MF0
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Canis familiaris)	BDBM50359981 (CHEMBL1927770) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of Met-triggered cell scattering in HGF-stimulated MDCK cells preincubated for overnight before HGF challenge measured after 24 to 48 hrs				Bioorg Med Chem Lett 22: 4693-6 (2012) Article DOI: 10.1016/j.bmcl.2012.05.078 BindingDB Entry DOI: 10.7270/Q2PV6MF0
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Canis familiaris)	BDBM50387355 (CHEMBL2046801) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of Met-triggered cell scattering in HGF-stimulated MDCK cells preincubated for overnight before HGF challenge measured after 24 to 48 hrs				Bioorg Med Chem Lett 22: 4693-6 (2012) Article DOI: 10.1016/j.bmcl.2012.05.078 BindingDB Entry DOI: 10.7270/Q2PV6MF0
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%