Found 72 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387437
(CHEMBL2047450)Show InChI InChI=1S/C14H17ClN4O/c1-18-2-4-19(5-3-18)14(20)12-7-9-6-10(15)8-11(16)13(9)17-12/h6-8,17H,2-5,16H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.01 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM22566
(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)Show InChI InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
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| Article
PubMed
| 6.31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50133018
((4,5-Dichloro-1H-indol-2-yl)-(4-methyl-piperazin-1...)Show InChI InChI=1S/C14H15Cl2N3O/c1-18-4-6-19(7-5-18)14(20)12-8-9-11(17-12)3-2-10(15)13(9)16/h2-3,8,17H,4-7H2,1H3 | PDB
Reactome pathway
KEGG
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DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| 6.31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387434
(CHEMBL2047447)Show InChI InChI=1S/C14H15ClFN3O/c1-18-4-6-19(7-5-18)14(20)12-8-9-11(17-12)3-2-10(15)13(9)16/h2-3,8,17H,4-7H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387436
(CHEMBL2047449)Show InChI InChI=1S/C15H18ClN3O/c1-10-7-12(16)8-11-9-13(17-14(10)11)15(20)19-5-3-18(2)4-6-19/h7-9,17H,3-6H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387435
(CHEMBL2047448)Show InChI InChI=1S/C14H15ClFN3O/c1-18-2-4-19(5-3-18)14(20)12-7-9-6-10(15)8-11(16)13(9)17-12/h6-8,17H,2-5H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387449
(CHEMBL2047466)Show InChI InChI=1S/C16H18ClN3O/c17-12-3-4-14-11(7-12)8-15(18-14)16(21)20-9-13(10-20)19-5-1-2-6-19/h3-4,7-8,13,18H,1-2,5-6,9-10H2 | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387438
(CHEMBL2047451)Show InChI InChI=1S/C14H16ClN3O/c1-9-6-11(15)7-10-8-12(17-13(9)10)14(19)18-4-2-16-3-5-18/h6-8,16-17H,2-5H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 12.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM26391
(5-chloro-2-(piperazin-1-ylcarbonyl)-1H-indole | JN...)Show InChI InChI=1S/C13H14ClN3O/c14-10-1-2-11-9(7-10)8-12(16-11)13(18)17-5-3-15-4-6-17/h1-2,7-8,15-16H,3-6H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 12.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50132999
((7-Methyl-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)...)Show InChI InChI=1S/C15H19N3O/c1-11-4-3-5-12-10-13(16-14(11)12)15(19)18-8-6-17(2)7-9-18/h3-5,10,16H,6-9H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 12.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50132996
((5-Fluoro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)...)Show InChI InChI=1S/C14H16FN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 15.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387452
(CHEMBL2047470)Show SMILES Fc1cc(Cl)cc2cc([nH]c12)C(=O)N1CC(C1)N1CCCC1 Show InChI InChI=1S/C16H17ClFN3O/c17-11-5-10-6-14(19-15(10)13(18)7-11)16(22)21-8-12(9-21)20-3-1-2-4-20/h5-7,12,19H,1-4,8-9H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 15.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50133004
((7-Amino-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-...)Show InChI InChI=1S/C14H18N4O/c1-17-5-7-18(8-6-17)14(19)12-9-10-3-2-4-11(15)13(10)16-12/h2-4,9,16H,5-8,15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 15.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387427
(CHEMBL2047276)Show InChI InChI=1S/C14H16FN3O/c1-17-5-7-18(8-6-17)14(19)12-9-10-3-2-4-11(15)13(10)16-12/h2-4,9,16H,5-8H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 19.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387467
(CHEMBL2047473)Show InChI InChI=1S/C13H13ClFN3O/c14-9-5-8-6-11(17-12(8)10(15)7-9)13(19)18-3-1-16-2-4-18/h5-7,16-17H,1-4H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 19.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50133016
((7-Chloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)...)Show InChI InChI=1S/C14H16ClN3O/c1-17-5-7-18(8-6-17)14(19)12-9-10-3-2-4-11(15)13(10)16-12/h2-4,9,16H,5-8H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 19.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387424
(CHEMBL2047273)Show InChI InChI=1S/C14H17N3O2/c1-16-4-6-17(7-5-16)14(19)13-8-10-2-3-11(18)9-12(10)15-13/h2-3,8-9,15,18H,4-7H2,1H3 | PDB
Reactome pathway
KEGG
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GoogleScholar
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| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 25.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50133007
((5-Hydroxy-1H-indol-2-yl)-(4-methyl-piperazin-1-yl...)Show InChI InChI=1S/C14H17N3O2/c1-16-4-6-17(7-5-16)14(19)13-9-10-8-11(18)2-3-12(10)15-13/h2-3,8-9,15,18H,4-7H2,1H3 | PDB
Reactome pathway
KEGG
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antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 25.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50133020
((1H-Indol-2-yl)-(4-methyl-piperazin-1-yl)-methanon...)Show InChI InChI=1S/C14H17N3O/c1-16-6-8-17(9-7-16)14(18)13-10-11-4-2-3-5-12(11)15-13/h2-5,10,15H,6-9H2,1H3 | PDB
Reactome pathway
KEGG
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AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 25.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50133001
((5-Amino-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-...)Show InChI InChI=1S/C14H18N4O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7,15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 31.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387451
(CHEMBL2047469)Show InChI InChI=1S/C15H17ClFN3O/c1-19-5-2-6-20(8-7-19)15(21)13-9-10-12(18-13)4-3-11(16)14(10)17/h3-4,9,18H,2,5-8H2,1H3 | PDB
Reactome pathway
KEGG
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DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 31.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387459
(CHEMBL2047263)Show InChI InChI=1S/C14H16FN3O/c1-17-5-7-18(8-6-17)14(19)13-9-10-11(15)3-2-4-12(10)16-13/h2-4,9,16H,5-8H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 31.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387469
(CHEMBL2047264)Show InChI InChI=1S/C14H16ClN3O/c1-17-5-7-18(8-6-17)14(19)13-9-10-11(15)3-2-4-12(10)16-13/h2-4,9,16H,5-8H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 31.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387464
(CHEMBL2047454)Show SMILES Cc1cc(Cl)cc2cc([nH]c12)C(=O)N1CC(C1)N1CCCC1 Show InChI InChI=1S/C17H20ClN3O/c1-11-6-13(18)7-12-8-15(19-16(11)12)17(22)21-9-14(10-21)20-4-2-3-5-20/h6-8,14,19H,2-5,9-10H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 31.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387446
(CHEMBL2047462)Show InChI InChI=1S/C16H18FN3O/c17-13-5-3-4-11-8-14(18-15(11)13)16(21)20-9-12(10-20)19-6-1-2-7-19/h3-5,8,12,18H,1-2,6-7,9-10H2 | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| 39.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387455
(CHEMBL2047475)Show InChI InChI=1S/C15H18FN3O/c1-10-3-4-12(16)11-9-13(17-14(10)11)15(20)19-7-5-18(2)6-8-19/h3-4,9,17H,5-8H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 39.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387440
(CHEMBL2047455)Show InChI InChI=1S/C15H18ClN3O/c1-18-5-2-6-19(8-7-18)15(20)14-10-11-9-12(16)3-4-13(11)17-14/h3-4,9-10,17H,2,5-8H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 39.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387471
(CHEMBL2047443)Show InChI InChI=1S/C14H17N3O/c1-10-3-2-4-11-9-12(16-13(10)11)14(18)17-7-5-15-6-8-17/h2-4,9,15-16H,5-8H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 39.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50133017
((5-methyl-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)...)Show InChI InChI=1S/C15H19N3O/c1-11-3-4-13-12(9-11)10-14(16-13)15(19)18-7-5-17(2)6-8-18/h3-4,9-10,16H,5-8H2,1-2H3 | PDB
Reactome pathway
KEGG
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DrugBank
antibodypedia
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| Purchase
CHEMBL
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PC sid
UniChem
Patents
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| Article
PubMed
| 50.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387475
(CHEMBL2047468)Show InChI InChI=1S/C15H17ClFN3O/c1-19-3-2-4-20(6-5-19)15(21)13-8-10-7-11(16)9-12(17)14(10)18-13/h7-9,18H,2-6H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 63.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387450
(CHEMBL2047467)Show InChI InChI=1S/C14H16ClN3O/c15-11-2-3-12-10(8-11)9-13(17-12)14(19)18-6-1-4-16-5-7-18/h2-3,8-9,16-17H,1,4-7H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 63.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387476
(CHEMBL2047476)Show InChI InChI=1S/C14H15F2N3O/c1-18-4-6-19(7-5-18)14(20)12-8-9-10(15)2-3-11(16)13(9)17-12/h2-3,8,17H,4-7H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 79.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387421
(CHEMBL2047270)Show SMILES CN1CCN(CC1)C(=O)c1cc2cc(ccc2[nH]1)[N+]([O-])=O Show InChI InChI=1S/C14H16N4O3/c1-16-4-6-17(7-5-16)14(19)13-9-10-8-11(18(20)21)2-3-12(10)15-13/h2-3,8-9,15H,4-7H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 79.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387426
(CHEMBL2047275)Show InChI InChI=1S/C14H18N4O/c1-17-4-6-18(7-5-17)14(19)13-8-10-2-3-11(15)9-12(10)16-13/h2-3,8-9,16H,4-7,15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 79.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387433
(CHEMBL2047446)Show InChI InChI=1S/C17H21N3O/c1-12-5-4-6-13-9-15(18-16(12)13)17(21)20-10-14(11-20)19-7-2-3-8-19/h4-6,9,14,18H,2-3,7-8,10-11H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 79.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387453
(CHEMBL2047471)Show InChI InChI=1S/C13H13ClFN3O/c1-16-9-5-18(6-9)13(19)11-3-7-2-8(14)4-10(15)12(7)17-11/h2-4,9,16-17H,5-6H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387474
(CHEMBL2047463)Show InChI InChI=1S/C13H14FN3O/c14-10-3-1-2-9-8-11(16-12(9)10)13(18)17-6-4-15-5-7-17/h1-3,8,15-16H,4-7H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387461
(CHEMBL2047266)Show InChI InChI=1S/C14H17N3O2/c1-16-5-7-17(8-6-16)14(19)12-9-10-11(15-12)3-2-4-13(10)18/h2-4,9,15,18H,5-8H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387423
(CHEMBL2047272)Show InChI InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-8-10-2-3-11(15)9-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387439
(CHEMBL2047453)Show InChI InChI=1S/C14H16ClN3O/c1-8-3-10(15)4-9-5-12(17-13(8)9)14(19)18-6-11(7-18)16-2/h3-5,11,16-17H,6-7H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387473
(CHEMBL2047458)Show InChI InChI=1S/C15H18FN3O/c1-18-6-3-7-19(9-8-18)15(20)14-10-11-12(16)4-2-5-13(11)17-14/h2,4-5,10,17H,3,6-9H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387465
(CHEMBL2047472)Show SMILES CN[C@@H]1CCN(C1)C(=O)c1cc2cc(Cl)cc(F)c2[nH]1 |r| Show InChI InChI=1S/C14H15ClFN3O/c1-17-10-2-3-19(7-10)14(20)12-5-8-4-9(15)6-11(16)13(8)18-12/h4-6,10,17-18H,2-3,7H2,1H3/t10-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387466
(CHEMBL2047259)Show InChI InChI=1S/C14H15ClN2O2/c1-16-4-6-17(7-5-16)14(18)13-9-10-8-11(15)2-3-12(10)19-13/h2-3,8-9H,4-7H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387472
(CHEMBL2047452)Show SMILES CN[C@@H]1CCN(C1)C(=O)c1cc2cc(Cl)cc(C)c2[nH]1 |r| Show InChI InChI=1S/C15H18ClN3O/c1-9-5-11(16)6-10-7-13(18-14(9)10)15(20)19-4-3-12(8-19)17-2/h5-7,12,17-18H,3-4,8H2,1-2H3/t12-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387463
(CHEMBL2047268)Show InChI InChI=1S/C14H18N4O/c1-17-5-7-18(8-6-17)14(19)13-9-10-11(15)3-2-4-12(10)16-13/h2-4,9,16H,5-8,15H2,1H3 | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387444
(CHEMBL2047460)Show InChI InChI=1S/C15H18FN3O/c1-18-6-3-7-19(9-8-18)15(20)13-10-11-4-2-5-12(16)14(11)17-13/h2,4-5,10,17H,3,6-9H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387454
(CHEMBL2047474)Show SMILES CN1CCN(CC1)C(=O)c1cc2cc(Cl)cc([N+]([O-])=O)c2[nH]1 Show InChI InChI=1S/C14H15ClN4O3/c1-17-2-4-18(5-3-17)14(20)11-7-9-6-10(15)8-12(19(21)22)13(9)16-11/h6-8,16H,2-5H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387448
(CHEMBL2047465)Show InChI InChI=1S/C13H14FN3O/c1-15-9-6-17(7-9)13(18)11-5-8-3-2-4-10(14)12(8)16-11/h2-5,9,15-16H,6-7H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387432
(CHEMBL2047445)Show InChI InChI=1S/C14H17N3O/c1-9-4-3-5-10-6-12(16-13(9)10)14(18)17-7-11(8-17)15-2/h3-6,11,15-16H,7-8H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387441
(CHEMBL2047456)Show InChI InChI=1S/C15H19N3O/c1-17-7-4-8-18(10-9-17)15(19)14-11-12-5-2-3-6-13(12)16-14/h2-3,5-6,11,16H,4,7-10H2,1H3 | PDB
Reactome pathway
KEGG
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| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387447
(CHEMBL2047464)Show SMILES CN[C@@H]1CCN(C1)C(=O)c1cc2cccc(F)c2[nH]1 |r| Show InChI InChI=1S/C14H16FN3O/c1-16-10-5-6-18(8-10)14(19)12-7-9-3-2-4-11(15)13(9)17-12/h2-4,7,10,16-17H,5-6,8H2,1H3/t10-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387431
(CHEMBL2047444)Show SMILES CN[C@@H]1CCN(C1)C(=O)c1cc2cccc(C)c2[nH]1 |r| Show InChI InChI=1S/C15H19N3O/c1-10-4-3-5-11-8-13(17-14(10)11)15(19)18-7-6-12(9-18)16-2/h3-5,8,12,16-17H,6-7,9H2,1-2H3/t12-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387462
(CHEMBL2047267)Show SMILES CN1CCN(CC1)C(=O)c1cc2c(cccc2[nH]1)[N+]([O-])=O Show InChI InChI=1S/C14H16N4O3/c1-16-5-7-17(8-6-16)14(19)12-9-10-11(15-12)3-2-4-13(10)18(20)21/h2-4,9,15H,5-8H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387429
(CHEMBL2047441)Show SMILES CN1CCN(CC1)C(=O)c1cc2cccc([N+]([O-])=O)c2[nH]1 Show InChI InChI=1S/C14H16N4O3/c1-16-5-7-17(8-6-16)14(19)11-9-10-3-2-4-12(18(20)21)13(10)15-11/h2-4,9,15H,5-8H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50132997
((5-Methoxy-1H-indol-2-yl)-(4-methyl-piperazin-1-yl...)Show InChI InChI=1S/C15H19N3O2/c1-17-5-7-18(8-6-17)15(19)14-10-11-9-12(20-2)3-4-13(11)16-14/h3-4,9-10,16H,5-8H2,1-2H3 | PDB
Reactome pathway
KEGG
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CHEMBL
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UniChem
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| Article
PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387460
(CHEMBL2047265)Show InChI InChI=1S/C15H19N3O2/c1-17-6-8-18(9-7-17)15(19)13-10-11-12(16-13)4-3-5-14(11)20-2/h3-5,10,16H,6-9H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387430
(CHEMBL2047442)Show InChI InChI=1S/C15H16F3N3O/c1-20-5-7-21(8-6-20)14(22)12-9-10-3-2-4-11(13(10)19-12)15(16,17)18/h2-4,9,19H,5-8H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387445
(CHEMBL2047461)Show InChI InChI=1S/C16H21N3O/c1-12-5-3-6-13-11-14(17-15(12)13)16(20)19-8-4-7-18(2)9-10-19/h3,5-6,11,17H,4,7-10H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387425
(CHEMBL2047274)Show SMILES CN1CCN(CC1)C(=O)c1cc2ccc(cc2[nH]1)[N+]([O-])=O Show InChI InChI=1S/C14H16N4O3/c1-16-4-6-17(7-5-16)14(19)13-8-10-2-3-11(18(20)21)9-12(10)15-13/h2-3,8-9,15H,4-7H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387458
(CHEMBL2047262)Show InChI InChI=1S/C13H16N4O/c1-16-4-6-17(7-5-16)13(18)11-8-10-2-3-14-9-12(10)15-11/h2-3,8-9,15H,4-7H2,1H3 | PDB
Reactome pathway
KEGG
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DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50362202
(CHEMBL1938843)Show InChI InChI=1S/C13H16N4O/c1-16-5-7-17(8-6-16)13(18)11-9-10-3-2-4-14-12(10)15-11/h2-4,9H,5-8H2,1H3,(H,14,15) | PDB
Reactome pathway
KEGG
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387428
(CHEMBL2047440)Show InChI InChI=1S/C15H19N3O2/c1-17-6-8-18(9-7-17)15(19)12-10-11-4-3-5-13(20-2)14(11)16-12/h3-5,10,16H,6-9H2,1-2H3 | PDB
Reactome pathway
KEGG
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DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387456
(CHEMBL2047258)Show InChI InChI=1S/C14H16N2OS/c1-15-6-8-16(9-7-15)14(17)13-10-11-4-2-3-5-12(11)18-13/h2-5,10H,6-9H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387468
(CHEMBL2047260)Show InChI InChI=1S/C13H16N4O/c1-16-5-7-17(8-6-16)13(18)12-9-11-10(15-12)3-2-4-14-11/h2-4,9,15H,5-8H2,1H3 | PDB
Reactome pathway
KEGG
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| Purchase
CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387420
(CHEMBL2047269)Show InChI InChI=1S/C16H19N3O2/c1-11(20)12-4-3-5-14-13(12)10-15(17-14)16(21)19-8-6-18(2)7-9-19/h3-5,10,17H,6-9H2,1-2H3 | PDB
Reactome pathway
KEGG
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387442
(CHEMBL2047457)Show SMILES CN1CCCN(CC1)C(=O)c1cc2cccc(c2[nH]1)C(F)(F)F Show InChI InChI=1S/C16H18F3N3O/c1-21-6-3-7-22(9-8-21)15(23)13-10-11-4-2-5-12(14(11)20-13)16(17,18)19/h2,4-5,10,20H,3,6-9H2,1H3 | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387457
(CHEMBL2047261)Show InChI InChI=1S/C13H16N4O/c1-16-4-6-17(7-5-16)13(18)12-8-10-9-14-3-2-11(10)15-12/h2-3,8-9,15H,4-7H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387422
(CHEMBL2047271)Show InChI InChI=1S/C16H19N3O2/c1-11(20)12-3-4-14-13(9-12)10-15(17-14)16(21)19-7-5-18(2)6-8-19/h3-4,9-10,17H,5-8H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387470
(CHEMBL1437043)Show InChI InChI=1S/C15H19N3O2/c1-17-5-7-18(8-6-17)15(19)14-9-11-3-4-12(20-2)10-13(11)16-14/h3-4,9-10,16H,5-8H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50387443
(CHEMBL2047459)Show InChI InChI=1S/C16H21N3O2/c1-18-7-4-8-19(10-9-18)16(20)13-11-12-5-3-6-14(21-2)15(12)17-13/h3,5-6,11,17H,4,7-10H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Mus musculus (mouse)) | BDBM22566
(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)Show InChI InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Inhibition of histamine H4 receptor-mediated chemotaxis in mouse bone marrow cells |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM22566
(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)Show InChI InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG
Curated by ChEMBL
| Assay Description
Inhibition of histamine H4 receptor-mediated chemotaxis in human eosinophils |
Eur J Med Chem 54: 660-8 (2012)
Article DOI: 10.1016/j.ejmech.2012.06.016
BindingDB Entry DOI: 10.7270/Q2251K7H |
More data for this
Ligand-Target Pair | |
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