Found 28 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387669
(CHEMBL2058071)Show SMILES [O-][N+](=O)c1ccccc1NC(=O)[C@@H]1CCCN1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 |r,TLB:28:27:20.21.26:23.24,THB:19:20:27:23.24| Show InChI InChI=1S/C30H32FN5O4/c31-22-10-9-20-14-19(7-8-21(20)15-22)18-35-24-11-12-25(35)17-23(16-24)32-30(38)34-13-3-6-28(34)29(37)33-26-4-1-2-5-27(26)36(39)40/h1-2,4-5,7-10,14-15,23-25,28H,3,6,11-13,16-18H2,(H,32,38)(H,33,37)/t24-,25-,28+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387649
(CHEMBL2057751)Show SMILES Nc1ccc2n(C3CCN(CC3)C(=O)NC3C[C@H]4CC[C@H](C3)N4Cc3ccc4cc(F)ccc4c3)c(=O)[nH]c2c1 |r,TLB:23:22:15.16.21:18.19,THB:14:15:22:18.19| Show InChI InChI=1S/C31H35FN6O2/c32-22-4-3-20-13-19(1-2-21(20)14-22)18-37-26-6-7-27(37)17-24(16-26)34-30(39)36-11-9-25(10-12-36)38-29-8-5-23(33)15-28(29)35-31(38)40/h1-5,8,13-15,24-27H,6-7,9-12,16-18,33H2,(H,34,39)(H,35,40)/t26-,27-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387664
(CHEMBL2057766)Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC[C@H]3C(=O)Nc3ccccc3F)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C30H32F2N4O2/c31-22-10-9-20-14-19(7-8-21(20)15-22)18-36-24-11-12-25(36)17-23(16-24)33-30(38)35-13-3-6-28(35)29(37)34-27-5-2-1-4-26(27)32/h1-2,4-5,7-10,14-15,23-25,28H,3,6,11-13,16-18H2,(H,33,38)(H,34,37)/t24-,25-,28+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387661
(CHEMBL2057763)Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC[C@H]3C(=O)Nc3ccccc3Br)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C30H32BrFN4O2/c31-26-4-1-2-5-27(26)34-29(37)28-6-3-13-35(28)30(38)33-23-16-24-11-12-25(17-23)36(24)18-19-7-8-21-15-22(32)10-9-20(21)14-19/h1-2,4-5,7-10,14-15,23-25,28H,3,6,11-13,16-18H2,(H,33,38)(H,34,37)/t24-,25-,28+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387654
(CHEMBL2057756)Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCCN(Cc4c(Cl)cccc4Cl)CC3)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C31H35Cl2FN4O/c32-29-3-1-4-30(33)28(29)20-36-11-2-12-37(14-13-36)31(39)35-25-17-26-9-10-27(18-25)38(26)19-21-5-6-23-16-24(34)8-7-22(23)15-21/h1,3-8,15-16,25-27H,2,9-14,17-20H2,(H,35,39)/t26-,27-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387642
(CHEMBL2057491)Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3-c3ccccc3)ccc2c1 |r,TLB:16:14:8:10.11| Show InChI InChI=1S/C31H29FN2O/c32-25-13-12-23-16-21(10-11-24(23)17-25)20-34-27-14-15-28(34)19-26(18-27)33-31(35)30-9-5-4-8-29(30)22-6-2-1-3-7-22/h1-13,16-17,26-28H,14-15,18-20H2,(H,33,35)/t27-,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387665
(CHEMBL2058070)Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC[C@H]3C(=O)Nc3ccccc3Cl)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C30H32ClFN4O2/c31-26-4-1-2-5-27(26)34-29(37)28-6-3-13-35(28)30(38)33-23-16-24-11-12-25(17-23)36(24)18-19-7-8-21-15-22(32)10-9-20(21)14-19/h1-2,4-5,7-10,14-15,23-25,28H,3,6,11-13,16-18H2,(H,33,38)(H,34,37)/t24-,25-,28+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387667
(CHEMBL2058073)Show SMILES CC(C)c1ccccc1NC(=O)[C@@H]1CCCN1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 |r,TLB:28:27:20.21.26:23.24,THB:19:20:27:23.24| Show InChI InChI=1S/C33H39FN4O2/c1-21(2)29-6-3-4-7-30(29)36-32(39)31-8-5-15-37(31)33(40)35-26-18-27-13-14-28(19-26)38(27)20-22-9-10-24-17-25(34)12-11-23(24)16-22/h3-4,6-7,9-12,16-17,21,26-28,31H,5,8,13-15,18-20H2,1-2H3,(H,35,40)(H,36,39)/t27-,28-,31+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387666
(CHEMBL2058072)Show SMILES COc1ccccc1NC(=O)[C@@H]1CCCN1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 |r,TLB:27:26:19.20.25:22.23,THB:18:19:26:22.23| Show InChI InChI=1S/C31H35FN4O3/c1-39-29-7-3-2-5-27(29)34-30(37)28-6-4-14-35(28)31(38)33-24-17-25-12-13-26(18-24)36(25)19-20-8-9-22-16-23(32)11-10-21(22)15-20/h2-3,5,7-11,15-16,24-26,28H,4,6,12-14,17-19H2,1H3,(H,33,38)(H,34,37)/t25-,26-,28+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387648
(CHEMBL2057750)Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC(CC3)n3c4cccc(F)c4[nH]c3=O)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C31H33F2N5O2/c32-22-7-6-20-14-19(4-5-21(20)15-22)18-37-25-8-9-26(37)17-23(16-25)34-30(39)36-12-10-24(11-13-36)38-28-3-1-2-27(33)29(28)35-31(38)40/h1-7,14-15,23-26H,8-13,16-18H2,(H,34,39)(H,35,40)/t25-,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387658
(CHEMBL2057760)Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCCN(CC3)C(=O)C3(CC3)c3ccccc3)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C34H39FN4O2/c35-28-10-9-25-19-24(7-8-26(25)20-28)23-39-30-11-12-31(39)22-29(21-30)36-33(41)38-16-4-15-37(17-18-38)32(40)34(13-14-34)27-5-2-1-3-6-27/h1-3,5-10,19-20,29-31H,4,11-18,21-23H2,(H,36,41)/t30-,31-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387653
(CHEMBL2057755)Show SMILES Oc1cccc(F)c1C(=O)N1CCCN(CC1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 |r,TLB:28:27:20.21.26:23.24,THB:19:20:27:23.24| Show InChI InChI=1S/C31H34F2N4O3/c32-23-8-7-21-15-20(5-6-22(21)16-23)19-37-25-9-10-26(37)18-24(17-25)34-31(40)36-12-2-11-35(13-14-36)30(39)29-27(33)3-1-4-28(29)38/h1,3-8,15-16,24-26,38H,2,9-14,17-19H2,(H,34,40)/t25-,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387647
(CHEMBL2057749)Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC(CC3)n3c4ccccc4[nH]c3=O)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C31H34FN5O2/c32-23-8-7-21-15-20(5-6-22(21)16-23)19-36-26-9-10-27(36)18-24(17-26)33-30(38)35-13-11-25(12-14-35)37-29-4-2-1-3-28(29)34-31(37)39/h1-8,15-16,24-27H,9-14,17-19H2,(H,33,38)(H,34,39)/t26-,27-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387659
(CHEMBL2057761)Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCCN(CC3)S(=O)(=O)c3ccccc3)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C30H35FN4O3S/c31-25-10-9-23-17-22(7-8-24(23)18-25)21-35-27-11-12-28(35)20-26(19-27)32-30(36)33-13-4-14-34(16-15-33)39(37,38)29-5-2-1-3-6-29/h1-3,5-10,17-18,26-28H,4,11-16,19-21H2,(H,32,36)/t27-,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387646
(CHEMBL2057747)Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC4(CC3)N(CNC4=O)c3ccccc3)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C32H36FN5O2/c33-25-9-8-23-16-22(6-7-24(23)17-25)20-37-28-10-11-29(37)19-26(18-28)35-31(40)36-14-12-32(13-15-36)30(39)34-21-38(32)27-4-2-1-3-5-27/h1-9,16-17,26,28-29H,10-15,18-21H2,(H,34,39)(H,35,40)/t28-,29-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387652
(CHEMBL2057754)Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCCN(CC3)C(=O)c3c(Cl)cccc3Cl)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C31H33Cl2FN4O2/c32-27-3-1-4-28(33)29(27)30(39)36-11-2-12-37(14-13-36)31(40)35-24-17-25-9-10-26(18-24)38(25)19-20-5-6-22-16-23(34)8-7-21(22)15-20/h1,3-8,15-16,24-26H,2,9-14,17-19H2,(H,35,40)/t25-,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387657
(CHEMBL2057759)Show SMILES Oc1ccccc1C(=O)N1CCCN(CC1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 |r,TLB:27:26:19.20.25:22.23,THB:18:19:26:22.23| Show InChI InChI=1S/C31H35FN4O3/c32-24-9-8-22-16-21(6-7-23(22)17-24)20-36-26-10-11-27(36)19-25(18-26)33-31(39)35-13-3-12-34(14-15-35)30(38)28-4-1-2-5-29(28)37/h1-2,4-9,16-17,25-27,37H,3,10-15,18-20H2,(H,33,39)/t26-,27-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387662
(CHEMBL2057764)Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC[C@H]3C(=O)Nc3cccc(Br)c3)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C30H32BrFN4O2/c31-22-3-1-4-24(15-22)33-29(37)28-5-2-12-35(28)30(38)34-25-16-26-10-11-27(17-25)36(26)18-19-6-7-21-14-23(32)9-8-20(21)13-19/h1,3-4,6-9,13-15,25-28H,2,5,10-12,16-18H2,(H,33,37)(H,34,38)/t26-,27-,28+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387643
(CHEMBL2057490)Show SMILES Fc1ccc2C(=O)N(CCc2c1)C(=O)NCCCN1CCC(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H34FN3O2/c32-27-12-13-28-26(22-27)16-21-35(30(28)36)31(37)33-17-7-18-34-19-14-25(15-20-34)29(23-8-3-1-4-9-23)24-10-5-2-6-11-24/h1-6,8-13,22,25,29H,7,14-21H2,(H,33,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387660
(CHEMBL2057762)Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC[C@H]3C(=O)Nc3ccccc3)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C30H33FN4O2/c31-23-11-10-21-15-20(8-9-22(21)16-23)19-35-26-12-13-27(35)18-25(17-26)33-30(37)34-14-4-7-28(34)29(36)32-24-5-2-1-3-6-24/h1-3,5-6,8-11,15-16,25-28H,4,7,12-14,17-19H2,(H,32,36)(H,33,37)/t26-,27-,28+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387650
(CHEMBL2057752)Show SMILES Fc1ccc(cc1)C(=O)N1CCCN(CC1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 |r,TLB:27:26:19.20.25:22.23,THB:18:19:26:22.23| Show InChI InChI=1S/C31H34F2N4O2/c32-25-7-4-22(5-8-25)30(38)35-12-1-13-36(15-14-35)31(39)34-27-18-28-10-11-29(19-27)37(28)20-21-2-3-24-17-26(33)9-6-23(24)16-21/h2-9,16-17,27-29H,1,10-15,18-20H2,(H,34,39)/t28-,29-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387668
(CHEMBL2057748)Show SMILES CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccc3cc(F)ccc3c2)C1=O |r,TLB:27:26:19.20.25:22.23,THB:18:19:26:22.23| Show InChI InChI=1S/C33H38FN5O2/c1-36-22-39(28-5-3-2-4-6-28)33(31(36)40)13-15-37(16-14-33)32(41)35-27-19-29-11-12-30(20-27)38(29)21-23-7-8-25-18-26(34)10-9-24(25)17-23/h2-10,17-18,27,29-30H,11-16,19-22H2,1H3,(H,35,41)/t29-,30-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387651
(CHEMBL2057753)Show SMILES Nc1ccc(cc1)C(=O)N1CCCN(CC1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 |r,TLB:27:26:19.20.25:22.23,THB:18:19:26:22.23| Show InChI InChI=1S/C31H36FN5O2/c32-25-7-4-23-16-21(2-3-24(23)17-25)20-37-28-10-11-29(37)19-27(18-28)34-31(39)36-13-1-12-35(14-15-36)30(38)22-5-8-26(33)9-6-22/h2-9,16-17,27-29H,1,10-15,18-20,33H2,(H,34,39)/t28-,29-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387656
(CHEMBL2057758)Show SMILES Oc1ccc(cc1)C(=O)N1CCCN(CC1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 |r,TLB:27:26:19.20.25:22.23,THB:18:19:26:22.23| Show InChI InChI=1S/C31H35FN4O3/c32-25-7-4-23-16-21(2-3-24(23)17-25)20-36-27-8-9-28(36)19-26(18-27)33-31(39)35-13-1-12-34(14-15-35)30(38)22-5-10-29(37)11-6-22/h2-7,10-11,16-17,26-28,37H,1,8-9,12-15,18-20H2,(H,33,39)/t27-,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387644
(CHEMBL2057489)Show SMILES Cc1nnc2n(CCCN3CCN(CC3)C(c3ccccc3)c3ccccc3)c(=O)c3ccccc3n12 Show InChI InChI=1S/C30H32N6O/c1-23-31-32-30-35(29(37)26-15-8-9-16-27(26)36(23)30)18-10-17-33-19-21-34(22-20-33)28(24-11-4-2-5-12-24)25-13-6-3-7-14-25/h2-9,11-16,28H,10,17-22H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387645
(CHEMBL2057746)Show SMILES Fc1ccc2CN(CCc2c1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 |r,TLB:22:21:14.15.20:17.18,THB:13:14:21:17.18| Show InChI InChI=1S/C28H29F2N3O/c29-23-5-3-19-11-18(1-2-20(19)12-23)16-33-26-7-8-27(33)15-25(14-26)31-28(34)32-10-9-21-13-24(30)6-4-22(21)17-32/h1-6,11-13,25-27H,7-10,14-17H2,(H,31,34)/t26-,27-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387663
(CHEMBL2057765)Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC[C@H]3C(=O)Nc3ccc(Br)cc3)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C30H32BrFN4O2/c31-22-6-9-24(10-7-22)33-29(37)28-2-1-13-35(28)30(38)34-25-16-26-11-12-27(17-25)36(26)18-19-3-4-21-15-23(32)8-5-20(21)14-19/h3-10,14-15,25-28H,1-2,11-13,16-18H2,(H,33,37)(H,34,38)/t26-,27-,28+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50387655
(CHEMBL2057757)Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCN(CC3)C(=O)c3c(Cl)cccc3Cl)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C30H31Cl2FN4O2/c31-26-2-1-3-27(32)28(26)29(38)35-10-12-36(13-11-35)30(39)34-23-16-24-8-9-25(17-23)37(24)18-19-4-5-21-15-22(33)7-6-20(21)14-19/h1-7,14-15,23-25H,8-13,16-18H2,(H,34,39)/t24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR3 |
Bioorg Med Chem Lett 22: 4951-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.042
BindingDB Entry DOI: 10.7270/Q2057H06 |
More data for this
Ligand-Target Pair | |
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