Affinity Data by PubMed id=22831801

PubMed code 22831801

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
P2Y purinoceptor 1 (Homo sapiens (Human))	BDBM50390013 (CHEMBL2071529) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [125I]MRS2500 from human P2Y1R expressed in Sf9 cell membrane				Bioorg Med Chem 20: 5254-61 (2012) Article DOI: 10.1016/j.bmc.2012.06.044 BindingDB Entry DOI: 10.7270/Q2BP03V2
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
P2Y purinoceptor 1 (Homo sapiens (Human))	BDBM50390014 (CHEMBL2071530) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [125I]MRS2500 from human P2Y1R expressed in Sf9 cell membrane				Bioorg Med Chem 20: 5254-61 (2012) Article DOI: 10.1016/j.bmc.2012.06.044 BindingDB Entry DOI: 10.7270/Q2BP03V2
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
P2Y purinoceptor 1 (Homo sapiens (Human))	BDBM59704 (1-(3,4-dichlorophenyl)-3-[4-[(3,4-dimethyl-1,2-oxa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [125I]MRS2500 from human P2Y1R expressed in Sf9 cell membrane				Bioorg Med Chem 20: 5254-61 (2012) Article DOI: 10.1016/j.bmc.2012.06.044 BindingDB Entry DOI: 10.7270/Q2BP03V2
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
P2Y purinoceptor 1 (Homo sapiens (Human))	BDBM50390015 (CHEMBL2071532) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [125I]MRS2500 from human P2Y1R expressed in Sf9 cell membrane				Bioorg Med Chem 20: 5254-61 (2012) Article DOI: 10.1016/j.bmc.2012.06.044 BindingDB Entry DOI: 10.7270/Q2BP03V2
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
P2Y purinoceptor 1 (Homo sapiens (Human))	BDBM50390016 (CHEMBL2071534) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [125I]MRS2500 from human P2Y1R expressed in Sf9 cell membrane				Bioorg Med Chem 20: 5254-61 (2012) Article DOI: 10.1016/j.bmc.2012.06.044 BindingDB Entry DOI: 10.7270/Q2BP03V2
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
P2Y purinoceptor 1 (Homo sapiens (Human))	BDBM50390017 (CHEMBL2071537) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [125I]MRS2500 from human P2Y1R expressed in Sf9 cell membrane				Bioorg Med Chem 20: 5254-61 (2012) Article DOI: 10.1016/j.bmc.2012.06.044 BindingDB Entry DOI: 10.7270/Q2BP03V2
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
P2Y purinoceptor 1 (Homo sapiens (Human))	BDBM50390018 (CHEMBL2071539) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Antagonist activity at human P2Y1R expressed in human 1321N1 cells assessed as inhibition of 2-MeSADP-induced increase in intracellular inositol phos...				Bioorg Med Chem 20: 5254-61 (2012) Article DOI: 10.1016/j.bmc.2012.06.044 BindingDB Entry DOI: 10.7270/Q2BP03V2
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
P2Y purinoceptor 1 (Homo sapiens (Human))	BDBM59704 (1-(3,4-dichlorophenyl)-3-[4-[(3,4-dimethyl-1,2-oxa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Antagonist activity at human P2Y1R expressed in human 1321N1 cells assessed as inhibition of 2-MeSADP-induced increase in intracellular inositol phos...				Bioorg Med Chem 20: 5254-61 (2012) Article DOI: 10.1016/j.bmc.2012.06.044 BindingDB Entry DOI: 10.7270/Q2BP03V2
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%