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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human)) | BDBM50390489 (CHEMBL2071602) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem | Article PubMed | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Miami Curated by ChEMBL | Assay Description Inhibition of ERBB2 autophosphorylation Thr 1139 residue in human BT474 cells at 2 to 14 uM after 12 hrs by fluorescence assay | Bioorg Med Chem Lett 22: 5532-5 (2012) Article DOI: 10.1016/j.bmcl.2012.07.034 BindingDB Entry DOI: 10.7270/Q2N017MV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human)) | BDBM50390489 (CHEMBL2071602) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a |
University of Miami Curated by ChEMBL | Assay Description Binding affinity to full-lenght/His-tagged ERBB2 UV-vis emission spectroscopy | Bioorg Med Chem Lett 22: 5532-5 (2012) Article DOI: 10.1016/j.bmcl.2012.07.034 BindingDB Entry DOI: 10.7270/Q2N017MV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
