Affinity Data by PubMed id=22929231

PubMed code 22929231

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50398332 (CHEMBL2177351) Show SMILES Oc1ccc(Br)cc1\C=C1/Oc2ccccc2C1=O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Campus Curated by ChEMBL					Assay Description Inhibition of full length recombinant human SIRT1 expressed in Escherichia coli BL21 (DE3) PLysS using Fluor-de-Lys as substrate by fluorimetric assa...				Bioorg Med Chem Lett 22: 6160-5 (2012) Article DOI: 10.1016/j.bmcl.2012.08.017 BindingDB Entry DOI: 10.7270/Q2CV4JWF
University of Hyderabad Campus Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50336799 (5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Campus Curated by ChEMBL					Assay Description Inhibition of full length recombinant human SIRT1 expressed in Escherichia coli BL21 (DE3) PLysS using Fluor-de-Lys as substrate by fluorimetric assa...				Bioorg Med Chem Lett 22: 6160-5 (2012) Article DOI: 10.1016/j.bmcl.2012.08.017 BindingDB Entry DOI: 10.7270/Q2CV4JWF
University of Hyderabad Campus Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50396053 (CHEMBL2170194) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Campus Curated by ChEMBL					Assay Description Inhibition of human SIRT2				Bioorg Med Chem Lett 22: 6160-5 (2012) Article DOI: 10.1016/j.bmcl.2012.08.017 BindingDB Entry DOI: 10.7270/Q2CV4JWF
University of Hyderabad Campus Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%