Found 102 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Delta-type opioid receptor
(MOUSE) | BDBM50391602
(CHEMBL2147915)Show SMILES CN1CC[C@]23Cc4nc5c(O)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H24N2O3/c1-26-8-7-23-13-19-16(9-15-3-2-4-20(28)22(15)25-19)12-24(23,29)21(26)10-14-5-6-17(27)11-18(14)23/h2-6,9,11,21,27-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.0920 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391591
(CHEMBL2147904)Show SMILES CN1CC[C@]23Cc4nc5cccc(F)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23FN2O2/c1-27-8-7-23-13-21-15(9-17-19(25)3-2-4-20(17)26-21)12-24(23,29)22(27)10-14-5-6-16(28)11-18(14)23/h2-6,9,11,22,28-29H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.143 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391594
(CHEMBL2147907)Show SMILES CN1CC[C@]23Cc4nc5c(F)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23FN2O2/c1-27-8-7-23-13-20-16(9-15-3-2-4-19(25)22(15)26-20)12-24(23,29)21(27)10-14-5-6-17(28)11-18(14)23/h2-6,9,11,21,28-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.146 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391595
(CHEMBL2147908)Show SMILES CN1CC[C@]23Cc4nc5cccc(C)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C25H26N2O2/c1-15-4-3-5-21-19(15)10-17-13-25(29)23-11-16-6-7-18(28)12-20(16)24(25,8-9-27(23)2)14-22(17)26-21/h3-7,10,12,23,28-29H,8-9,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.148 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391603
(CHEMBL2147916)Show SMILES COc1cccc2nc3C[C@]45CCN(C)[C@H](Cc6ccc(O)cc46)[C@]5(O)Cc3cc12 |r,TLB:14:13:24:23.17.16| Show InChI InChI=1S/C25H26N2O3/c1-27-9-8-24-14-21-16(10-18-20(26-21)4-3-5-22(18)30-2)13-25(24,29)23(27)11-15-6-7-17(28)12-19(15)24/h3-7,10,12,23,28-29H,8-9,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.151 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50329095
(CHEMBL1270282)Show SMILES CN1CC[C@]23Cc4nc5ccccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:17:21.27.20| Show InChI InChI=1S/C24H24N2O2/c1-26-9-8-23-14-21-17(10-16-4-2-3-5-20(16)25-21)13-24(23,28)22(26)11-15-6-7-18(27)12-19(15)23/h2-7,10,12,22,27-28H,8-9,11,13-14H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM21864
((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)Show SMILES [H][C@@]12Cc3ccc(O)c4OC5c6[nH]c7ccccc7c6CC1(O)C5(CCN2CC1CC1)c34 |THB:27:26:21:31.2.3| Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391582
(CHEMBL2147927)Show SMILES CN1CC[C@]23Cc4nc5c(cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)[N+]([O-])=O |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C24H23N3O4/c1-26-8-7-23-13-19-16(9-15-3-2-4-20(27(30)31)22(15)25-19)12-24(23,29)21(26)10-14-5-6-17(28)11-18(14)23/h2-6,9,11,21,28-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.218 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391590
(CHEMBL2147903)Show SMILES CN1CC[C@]23Cc4nc5c(Cl)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23ClN2O2/c1-27-8-7-23-13-20-16(9-15-3-2-4-19(25)22(15)26-20)12-24(23,29)21(27)10-14-5-6-17(28)11-18(14)23/h2-6,9,11,21,28-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.235 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391607
(CHEMBL2147920)Show SMILES CN1CC[C@]23Cc4nc5cccc(c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)C(F)(F)F |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C25H23F3N2O2/c1-30-8-7-23-13-21-15(9-17-18(25(26,27)28)3-2-4-20(17)29-21)12-24(23,32)22(30)10-14-5-6-16(31)11-19(14)23/h2-6,9,11,22,31-32H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.244 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391593
(CHEMBL2147906)Show SMILES CN1CC[C@]23Cc4nc5cc(F)ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23FN2O2/c1-27-7-6-23-13-21-16(8-15-2-4-17(25)10-20(15)26-21)12-24(23,29)22(27)9-14-3-5-18(28)11-19(14)23/h2-5,8,10-11,22,28-29H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.255 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391598
(CHEMBL2147911)Show SMILES CN1CC[C@]23Cc4nc5c(C)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C25H26N2O2/c1-15-4-3-5-17-10-18-13-25(29)22-11-16-6-7-19(28)12-20(16)24(25,8-9-27(22)2)14-21(18)26-23(15)17/h3-7,10,12,22,28-29H,8-9,11,13-14H2,1-2H3/t22-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.267 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391601
(CHEMBL2147914)Show SMILES CN1CC[C@]23Cc4nc5cc(O)ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H24N2O3/c1-26-7-6-23-13-21-16(8-15-3-5-18(28)11-20(15)25-21)12-24(23,29)22(26)9-14-2-4-17(27)10-19(14)23/h2-5,8,10-11,22,27-29H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391596
(CHEMBL2147909)Show SMILES CN1CC[C@]23Cc4nc5ccc(C)cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C25H26N2O2/c1-15-3-6-21-17(9-15)10-18-13-25(29)23-11-16-4-5-19(28)12-20(16)24(25,7-8-27(23)2)14-22(18)26-21/h3-6,9-10,12,23,28-29H,7-8,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391579
(CHEMBL2147924)Show SMILES CN1CC[C@]23Cc4nc5cccc([N+]([O-])=O)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:20:30.24.23| Show InChI InChI=1S/C24H23N3O4/c1-26-8-7-23-13-20-15(9-17-19(25-20)3-2-4-21(17)27(30)31)12-24(23,29)22(26)10-14-5-6-16(28)11-18(14)23/h2-6,9,11,22,28-29H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.344 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391587
(CHEMBL2147891)Show SMILES CN1CC[C@]23Cc4nc5cccc(Cl)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23ClN2O2/c1-27-8-7-23-13-21-15(9-17-19(25)3-2-4-20(17)26-21)12-24(23,29)22(27)10-14-5-6-16(28)11-18(14)23/h2-6,9,11,22,28-29H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.353 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391597
(CHEMBL2147910)Show SMILES CN1CC[C@]23Cc4nc5cc(C)ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C25H26N2O2/c1-15-3-4-17-10-18-13-25(29)23-11-16-5-6-19(28)12-20(16)24(25,7-8-27(23)2)14-22(18)26-21(17)9-15/h3-6,9-10,12,23,28-29H,7-8,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.362 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391589
(CHEMBL2147902)Show SMILES CN1CC[C@]23Cc4nc5cc(Cl)ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23ClN2O2/c1-27-7-6-23-13-21-16(8-15-2-4-17(25)10-20(15)26-21)12-24(23,29)22(27)9-14-3-5-18(28)11-19(14)23/h2-5,8,10-11,22,28-29H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.403 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391578
(CHEMBL2147923)Show SMILES CN1CC[C@]23Cc4nc5c(cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)C(F)(F)F |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C25H23F3N2O2/c1-30-8-7-23-13-20-16(9-15-3-2-4-18(22(15)29-20)25(26,27)28)12-24(23,32)21(30)10-14-5-6-17(31)11-19(14)23/h2-6,9,11,21,31-32H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.493 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391606
(CHEMBL2147919)Show SMILES COc1cccc2cc3C[C@@]4(O)[C@H]5Cc6ccc(O)cc6[C@@]4(CCN5C)Cc3nc12 |r,THB:25:24:10:20.14.13| Show InChI InChI=1S/C25H26N2O3/c1-27-9-8-24-14-20-17(10-16-4-3-5-21(30-2)23(16)26-20)13-25(24,29)22(27)11-15-6-7-18(28)12-19(15)24/h3-7,10,12,22,28-29H,8-9,11,13-14H2,1-2H3/t22-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.498 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391588
(CHEMBL2147901)Show SMILES CN1CC[C@]23Cc4nc5ccc(Cl)cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23ClN2O2/c1-27-7-6-23-13-21-16(8-15-9-17(25)3-5-20(15)26-21)12-24(23,29)22(27)10-14-2-4-18(28)11-19(14)23/h2-5,8-9,11,22,28-29H,6-7,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.583 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391583
(CHEMBL2147928)Show SMILES CN(C)c1cccc2nc3C[C@]45CCN(C)[C@H](Cc6ccc(O)cc46)[C@]5(O)Cc3cc12 |r,TLB:15:14:25:24.18.17| Show InChI InChI=1S/C26H29N3O2/c1-28(2)23-6-4-5-21-19(23)11-17-14-26(31)24-12-16-7-8-18(30)13-20(16)25(26,9-10-29(24)3)15-22(17)27-21/h4-8,11,13,24,30-31H,9-10,12,14-15H2,1-3H3/t24-,25-,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.621 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391586
(CHEMBL2147931)Show SMILES CN(C)c1cccc2cc3C[C@@]4(O)[C@H]5Cc6ccc(O)cc6[C@@]4(CCN5C)Cc3nc12 |r,THB:26:25:11:21.15.14| Show InChI InChI=1S/C26H29N3O2/c1-28(2)22-6-4-5-17-11-18-14-26(31)23-12-16-7-8-19(30)13-20(16)25(26,9-10-29(23)3)15-21(18)27-24(17)22/h4-8,11,13,23,30-31H,9-10,12,14-15H2,1-3H3/t23-,25-,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391592
(CHEMBL2147905)Show SMILES CN1CC[C@]23Cc4nc5ccc(F)cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23FN2O2/c1-27-7-6-23-13-21-16(8-15-9-17(25)3-5-20(15)26-21)12-24(23,29)22(27)10-14-2-4-18(28)11-19(14)23/h2-5,8-9,11,22,28-29H,6-7,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.730 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391605
(CHEMBL2147918)Show SMILES COc1ccc2cc3C[C@@]4(O)[C@H]5Cc6ccc(O)cc6[C@@]4(CCN5C)Cc3nc2c1 |r,THB:24:23:9:19.13.12| Show InChI InChI=1S/C25H26N2O3/c1-27-8-7-24-14-22-17(9-16-4-6-19(30-2)12-21(16)26-22)13-25(24,29)23(27)10-15-3-5-18(28)11-20(15)24/h3-6,9,11-12,23,28-29H,7-8,10,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.808 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391604
(CHEMBL2147917)Show SMILES COc1ccc2nc3C[C@]45CCN(C)[C@H](Cc6ccc(O)cc46)[C@]5(O)Cc3cc2c1 |r,TLB:13:12:23:22.16.15| Show InChI InChI=1S/C25H26N2O3/c1-27-8-7-24-14-22-17(9-16-10-19(30-2)5-6-21(16)26-22)13-25(24,29)23(27)11-15-3-4-18(28)12-20(15)24/h3-6,9-10,12,23,28-29H,7-8,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.874 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391608
(CHEMBL2147921)Show SMILES CN1CC[C@]23Cc4nc5ccc(cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)C(F)(F)F |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C25H23F3N2O2/c1-30-7-6-23-13-21-16(8-15-9-17(25(26,27)28)3-5-20(15)29-21)12-24(23,32)22(30)10-14-2-4-18(31)11-19(14)23/h2-5,8-9,11,22,31-32H,6-7,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.923 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391584
(CHEMBL2147929)Show SMILES CN(C)c1ccc2nc3C[C@]45CCN(C)[C@H](Cc6ccc(O)cc46)[C@]5(O)Cc3cc2c1 |r,TLB:14:13:24:23.17.16| Show InChI InChI=1S/C26H29N3O2/c1-28(2)19-5-7-22-17(11-19)10-18-14-26(31)24-12-16-4-6-20(30)13-21(16)25(26,8-9-29(24)3)15-23(18)27-22/h4-7,10-11,13,24,30-31H,8-9,12,14-15H2,1-3H3/t24-,25-,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.963 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391581
(CHEMBL2147926)Show SMILES CN1CC[C@]23Cc4nc5cc(ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)[N+]([O-])=O |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C24H23N3O4/c1-26-7-6-23-13-21-16(8-15-2-4-17(27(30)31)10-20(15)25-21)12-24(23,29)22(26)9-14-3-5-18(28)11-19(14)23/h2-5,8,10-11,22,28-29H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391609
(CHEMBL2147922)Show SMILES CN1CC[C@]23Cc4nc5cc(ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)C(F)(F)F |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C25H23F3N2O2/c1-30-7-6-23-13-21-16(8-15-2-4-17(25(26,27)28)10-20(15)29-21)12-24(23,32)22(30)9-14-3-5-18(31)11-19(14)23/h2-5,8,10-11,22,31-32H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391585
(CHEMBL2147930)Show SMILES CN(C)c1ccc2cc3C[C@@]4(O)[C@H]5Cc6ccc(O)cc6[C@@]4(CCN5C)Cc3nc2c1 |r,THB:25:24:10:20.14.13| Show InChI InChI=1S/C26H29N3O2/c1-28(2)19-6-4-17-10-18-14-26(31)24-11-16-5-7-20(30)13-21(16)25(26,8-9-29(24)3)15-23(18)27-22(17)12-19/h4-7,10,12-13,24,30-31H,8-9,11,14-15H2,1-3H3/t24-,25-,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391600
(CHEMBL2147913)Show SMILES CN1CC[C@]23Cc4nc5ccc(O)cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H24N2O3/c1-26-7-6-23-13-21-16(8-15-9-17(27)4-5-20(15)25-21)12-24(23,29)22(26)10-14-2-3-18(28)11-19(14)23/h2-5,8-9,11,22,27-29H,6-7,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391580
(CHEMBL2147925)Show SMILES CN1CC[C@]23Cc4nc5ccc(cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)[N+]([O-])=O |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C24H23N3O4/c1-26-7-6-23-13-21-16(8-15-9-17(27(30)31)3-5-20(15)25-21)12-24(23,29)22(26)10-14-2-4-18(28)11-19(14)23/h2-5,8-9,11,22,28-29H,6-7,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.66 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50391599
(CHEMBL2147912)Show SMILES CN1CC[C@]23Cc4nc5cccc(O)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H24N2O3/c1-26-8-7-23-13-20-15(9-17-19(25-20)3-2-4-21(17)28)12-24(23,29)22(26)10-14-5-6-16(27)11-18(14)23/h2-6,9,11,22,27-29H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.73 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391591
(CHEMBL2147904)Show SMILES CN1CC[C@]23Cc4nc5cccc(F)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23FN2O2/c1-27-8-7-23-13-21-15(9-17-19(25)3-2-4-20(17)26-21)12-24(23,29)22(27)10-14-5-6-16(28)11-18(14)23/h2-6,9,11,22,28-29H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.76 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391592
(CHEMBL2147905)Show SMILES CN1CC[C@]23Cc4nc5ccc(F)cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23FN2O2/c1-27-7-6-23-13-21-16(8-15-9-17(25)3-5-20(15)26-21)12-24(23,29)22(27)10-14-2-4-18(28)11-19(14)23/h2-5,8-9,11,22,28-29H,6-7,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
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UniChem
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PubMed
| 8.27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM21864
((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)Show SMILES [H][C@@]12Cc3ccc(O)c4OC5c6[nH]c7ccccc7c6CC1(O)C5(CCN2CC1CC1)c34 |THB:27:26:21:31.2.3| Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
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PC cid
PC sid
UniChem
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| Article
PubMed
| 9.04 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391593
(CHEMBL2147906)Show SMILES CN1CC[C@]23Cc4nc5cc(F)ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23FN2O2/c1-27-7-6-23-13-21-16(8-15-2-4-17(25)10-20(15)26-21)12-24(23,29)22(27)9-14-3-5-18(28)11-19(14)23/h2-5,8,10-11,22,28-29H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 10.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391600
(CHEMBL2147913)Show SMILES CN1CC[C@]23Cc4nc5ccc(O)cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H24N2O3/c1-26-7-6-23-13-21-16(8-15-9-17(27)4-5-20(15)25-21)12-24(23,29)22(26)10-14-2-3-18(28)11-19(14)23/h2-5,8-9,11,22,27-29H,6-7,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
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PC sid
UniChem
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PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391594
(CHEMBL2147907)Show SMILES CN1CC[C@]23Cc4nc5c(F)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23FN2O2/c1-27-8-7-23-13-20-16(9-15-3-2-4-19(25)22(15)26-20)12-24(23,29)21(27)10-14-5-6-17(28)11-18(14)23/h2-6,9,11,21,28-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
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PC sid
UniChem
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| Article
PubMed
| 12.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391579
(CHEMBL2147924)Show SMILES CN1CC[C@]23Cc4nc5cccc([N+]([O-])=O)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:20:30.24.23| Show InChI InChI=1S/C24H23N3O4/c1-26-8-7-23-13-20-15(9-17-19(25-20)3-2-4-21(17)27(30)31)12-24(23,29)22(26)10-14-5-6-16(28)11-18(14)23/h2-6,9,11,22,28-29H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| 12.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM21864
((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)Show SMILES [H][C@@]12Cc3ccc(O)c4OC5c6[nH]c7ccccc7c6CC1(O)C5(CCN2CC1CC1)c34 |THB:27:26:21:31.2.3| Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 | PDB
Reactome pathway
KEGG
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PC sid
UniChem
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| Article
PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391599
(CHEMBL2147912)Show SMILES CN1CC[C@]23Cc4nc5cccc(O)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H24N2O3/c1-26-8-7-23-13-20-15(9-17-19(25-20)3-2-4-21(17)28)12-24(23,29)22(26)10-14-5-6-16(27)11-18(14)23/h2-6,9,11,22,27-29H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 15.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391599
(CHEMBL2147912)Show SMILES CN1CC[C@]23Cc4nc5cccc(O)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H24N2O3/c1-26-8-7-23-13-20-15(9-17-19(25-20)3-2-4-21(17)28)12-24(23,29)22(26)10-14-5-6-16(27)11-18(14)23/h2-6,9,11,22,27-29H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 17.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391603
(CHEMBL2147916)Show SMILES COc1cccc2nc3C[C@]45CCN(C)[C@H](Cc6ccc(O)cc46)[C@]5(O)Cc3cc12 |r,TLB:14:13:24:23.17.16| Show InChI InChI=1S/C25H26N2O3/c1-27-9-8-24-14-21-16(10-18-20(26-21)4-3-5-22(18)30-2)13-25(24,29)23(27)11-15-6-7-17(28)12-19(15)24/h3-7,10,12,23,28-29H,8-9,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 20.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391601
(CHEMBL2147914)Show SMILES CN1CC[C@]23Cc4nc5cc(O)ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H24N2O3/c1-26-7-6-23-13-21-16(8-15-3-5-18(28)11-20(15)25-21)12-24(23,29)22(26)9-14-2-4-17(27)10-19(14)23/h2-5,8,10-11,22,27-29H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 20.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391581
(CHEMBL2147926)Show SMILES CN1CC[C@]23Cc4nc5cc(ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)[N+]([O-])=O |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C24H23N3O4/c1-26-7-6-23-13-21-16(8-15-2-4-17(27(30)31)10-20(15)25-21)12-24(23,29)22(26)9-14-3-5-18(28)11-19(14)23/h2-5,8,10-11,22,28-29H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 20.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50329095
(CHEMBL1270282)Show SMILES CN1CC[C@]23Cc4nc5ccccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:17:21.27.20| Show InChI InChI=1S/C24H24N2O2/c1-26-9-8-23-14-21-17(10-16-4-2-3-5-20(16)25-21)13-24(23,28)22(26)11-15-6-7-18(27)12-19(15)23/h2-7,10,12,22,27-28H,8-9,11,13-14H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 21.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391605
(CHEMBL2147918)Show SMILES COc1ccc2cc3C[C@@]4(O)[C@H]5Cc6ccc(O)cc6[C@@]4(CCN5C)Cc3nc2c1 |r,THB:24:23:9:19.13.12| Show InChI InChI=1S/C25H26N2O3/c1-27-8-7-24-14-22-17(9-16-4-6-19(30-2)12-21(16)26-22)13-25(24,29)23(27)10-15-3-5-18(28)11-20(15)24/h3-6,9,11-12,23,28-29H,7-8,10,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 21.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391601
(CHEMBL2147914)Show SMILES CN1CC[C@]23Cc4nc5cc(O)ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H24N2O3/c1-26-7-6-23-13-21-16(8-15-3-5-18(28)11-20(15)25-21)12-24(23,29)22(26)9-14-2-4-17(27)10-19(14)23/h2-5,8,10-11,22,27-29H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 22.0 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391586
(CHEMBL2147931)Show SMILES CN(C)c1cccc2cc3C[C@@]4(O)[C@H]5Cc6ccc(O)cc6[C@@]4(CCN5C)Cc3nc12 |r,THB:26:25:11:21.15.14| Show InChI InChI=1S/C26H29N3O2/c1-28(2)22-6-4-5-17-11-18-14-26(31)23-12-16-7-8-19(30)13-20(16)25(26,9-10-29(23)3)15-21(18)27-24(17)22/h4-8,11,13,23,30-31H,9-10,12,14-15H2,1-3H3/t23-,25-,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 22.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391600
(CHEMBL2147913)Show SMILES CN1CC[C@]23Cc4nc5ccc(O)cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H24N2O3/c1-26-7-6-23-13-21-16(8-15-9-17(27)4-5-20(15)25-21)12-24(23,29)22(26)10-14-2-3-18(28)11-19(14)23/h2-5,8-9,11,22,27-29H,6-7,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 22.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391580
(CHEMBL2147925)Show SMILES CN1CC[C@]23Cc4nc5ccc(cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)[N+]([O-])=O |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C24H23N3O4/c1-26-7-6-23-13-21-16(8-15-9-17(27(30)31)3-5-20(15)25-21)12-24(23,29)22(26)10-14-2-4-18(28)11-19(14)23/h2-5,8-9,11,22,28-29H,6-7,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 24.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391588
(CHEMBL2147901)Show SMILES CN1CC[C@]23Cc4nc5ccc(Cl)cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23ClN2O2/c1-27-7-6-23-13-21-16(8-15-9-17(25)3-5-20(15)26-21)12-24(23,29)22(27)10-14-2-4-18(28)11-19(14)23/h2-5,8-9,11,22,28-29H,6-7,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 24.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391582
(CHEMBL2147927)Show SMILES CN1CC[C@]23Cc4nc5c(cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)[N+]([O-])=O |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C24H23N3O4/c1-26-8-7-23-13-19-16(9-15-3-2-4-20(27(30)31)22(15)25-19)12-24(23,29)21(26)10-14-5-6-17(28)11-18(14)23/h2-6,9,11,21,28-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 27.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391589
(CHEMBL2147902)Show SMILES CN1CC[C@]23Cc4nc5cc(Cl)ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23ClN2O2/c1-27-7-6-23-13-21-16(8-15-2-4-17(25)10-20(15)26-21)12-24(23,29)22(27)9-14-3-5-18(28)11-19(14)23/h2-5,8,10-11,22,28-29H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 29.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391604
(CHEMBL2147917)Show SMILES COc1ccc2nc3C[C@]45CCN(C)[C@H](Cc6ccc(O)cc46)[C@]5(O)Cc3cc2c1 |r,TLB:13:12:23:22.16.15| Show InChI InChI=1S/C25H26N2O3/c1-27-8-7-24-14-22-17(9-16-10-19(30-2)5-6-21(16)26-22)13-25(24,29)23(27)11-15-3-4-18(28)12-20(15)24/h3-6,9-10,12,23,28-29H,7-8,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 29.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391595
(CHEMBL2147908)Show SMILES CN1CC[C@]23Cc4nc5cccc(C)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C25H26N2O2/c1-15-4-3-5-21-19(15)10-17-13-25(29)23-11-16-6-7-18(28)12-20(16)24(25,8-9-27(23)2)14-22(17)26-21/h3-7,10,12,23,28-29H,8-9,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 31.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391596
(CHEMBL2147909)Show SMILES CN1CC[C@]23Cc4nc5ccc(C)cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C25H26N2O2/c1-15-3-6-21-17(9-15)10-18-13-25(29)23-11-16-4-5-19(28)12-20(16)24(25,7-8-27(23)2)14-22(18)26-21/h3-6,9-10,12,23,28-29H,7-8,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 32.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391583
(CHEMBL2147928)Show SMILES CN(C)c1cccc2nc3C[C@]45CCN(C)[C@H](Cc6ccc(O)cc46)[C@]5(O)Cc3cc12 |r,TLB:15:14:25:24.18.17| Show InChI InChI=1S/C26H29N3O2/c1-28(2)23-6-4-5-21-19(23)11-17-14-26(31)24-12-16-7-8-18(30)13-20(16)25(26,9-10-29(24)3)15-22(17)27-21/h4-8,11,13,24,30-31H,9-10,12,14-15H2,1-3H3/t24-,25-,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 32.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391584
(CHEMBL2147929)Show SMILES CN(C)c1ccc2nc3C[C@]45CCN(C)[C@H](Cc6ccc(O)cc46)[C@]5(O)Cc3cc2c1 |r,TLB:14:13:24:23.17.16| Show InChI InChI=1S/C26H29N3O2/c1-28(2)19-5-7-22-17(11-19)10-18-14-26(31)24-12-16-4-6-20(30)13-21(16)25(26,8-9-29(24)3)15-23(18)27-22/h4-7,10-11,13,24,30-31H,8-9,12,14-15H2,1-3H3/t24-,25-,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 33.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391597
(CHEMBL2147910)Show SMILES CN1CC[C@]23Cc4nc5cc(C)ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C25H26N2O2/c1-15-3-4-17-10-18-13-25(29)23-11-16-5-6-19(28)12-20(16)24(25,7-8-27(23)2)14-22(18)26-21(17)9-15/h3-6,9-10,12,23,28-29H,7-8,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 34.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391590
(CHEMBL2147903)Show SMILES CN1CC[C@]23Cc4nc5c(Cl)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23ClN2O2/c1-27-8-7-23-13-20-16(9-15-3-2-4-19(25)22(15)26-20)12-24(23,29)21(27)10-14-5-6-17(28)11-18(14)23/h2-6,9,11,21,28-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 34.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391579
(CHEMBL2147924)Show SMILES CN1CC[C@]23Cc4nc5cccc([N+]([O-])=O)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:20:30.24.23| Show InChI InChI=1S/C24H23N3O4/c1-26-8-7-23-13-20-15(9-17-19(25-20)3-2-4-21(17)27(30)31)12-24(23,29)22(26)10-14-5-6-16(28)11-18(14)23/h2-6,9,11,22,28-29H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 36.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391606
(CHEMBL2147919)Show SMILES COc1cccc2cc3C[C@@]4(O)[C@H]5Cc6ccc(O)cc6[C@@]4(CCN5C)Cc3nc12 |r,THB:25:24:10:20.14.13| Show InChI InChI=1S/C25H26N2O3/c1-27-9-8-24-14-20-17(10-16-4-3-5-21(30-2)23(16)26-20)13-25(24,29)22(27)11-15-6-7-18(28)12-19(15)24/h3-7,10,12,22,28-29H,8-9,11,13-14H2,1-2H3/t22-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 39.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391602
(CHEMBL2147915)Show SMILES CN1CC[C@]23Cc4nc5c(O)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H24N2O3/c1-26-8-7-23-13-19-16(9-15-3-2-4-20(28)22(15)25-19)12-24(23,29)21(26)10-14-5-6-17(27)11-18(14)23/h2-6,9,11,21,27-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 45.0 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391587
(CHEMBL2147891)Show SMILES CN1CC[C@]23Cc4nc5cccc(Cl)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23ClN2O2/c1-27-8-7-23-13-21-15(9-17-19(25)3-2-4-20(17)26-21)12-24(23,29)22(27)10-14-5-6-16(28)11-18(14)23/h2-6,9,11,22,28-29H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 47.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391596
(CHEMBL2147909)Show SMILES CN1CC[C@]23Cc4nc5ccc(C)cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C25H26N2O2/c1-15-3-6-21-17(9-15)10-18-13-25(29)23-11-16-4-5-19(28)12-20(16)24(25,7-8-27(23)2)14-22(18)26-21/h3-6,9-10,12,23,28-29H,7-8,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 48.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391608
(CHEMBL2147921)Show SMILES CN1CC[C@]23Cc4nc5ccc(cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)C(F)(F)F |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C25H23F3N2O2/c1-30-7-6-23-13-21-16(8-15-9-17(25(26,27)28)3-5-20(15)29-21)12-24(23,32)22(30)10-14-2-4-18(31)11-19(14)23/h2-5,8-9,11,22,31-32H,6-7,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 52.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391587
(CHEMBL2147891)Show SMILES CN1CC[C@]23Cc4nc5cccc(Cl)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23ClN2O2/c1-27-8-7-23-13-21-15(9-17-19(25)3-2-4-20(17)26-21)12-24(23,29)22(27)10-14-5-6-16(28)11-18(14)23/h2-6,9,11,22,28-29H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 58.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391591
(CHEMBL2147904)Show SMILES CN1CC[C@]23Cc4nc5cccc(F)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23FN2O2/c1-27-8-7-23-13-21-15(9-17-19(25)3-2-4-20(17)26-21)12-24(23,29)22(27)10-14-5-6-16(28)11-18(14)23/h2-6,9,11,22,28-29H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 59.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391607
(CHEMBL2147920)Show SMILES CN1CC[C@]23Cc4nc5cccc(c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)C(F)(F)F |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C25H23F3N2O2/c1-30-8-7-23-13-21-15(9-17-18(25(26,27)28)3-2-4-20(17)29-21)12-24(23,32)22(30)10-14-5-6-16(31)11-19(14)23/h2-6,9,11,22,31-32H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 61.0 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391580
(CHEMBL2147925)Show SMILES CN1CC[C@]23Cc4nc5ccc(cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)[N+]([O-])=O |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C24H23N3O4/c1-26-7-6-23-13-21-16(8-15-9-17(27(30)31)3-5-20(15)25-21)12-24(23,29)22(26)10-14-2-4-18(28)11-19(14)23/h2-5,8-9,11,22,28-29H,6-7,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 65.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391602
(CHEMBL2147915)Show SMILES CN1CC[C@]23Cc4nc5c(O)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H24N2O3/c1-26-8-7-23-13-19-16(9-15-3-2-4-20(28)22(15)25-19)12-24(23,29)21(26)10-14-5-6-17(27)11-18(14)23/h2-6,9,11,21,27-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 67.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391585
(CHEMBL2147930)Show SMILES CN(C)c1ccc2cc3C[C@@]4(O)[C@H]5Cc6ccc(O)cc6[C@@]4(CCN5C)Cc3nc2c1 |r,THB:25:24:10:20.14.13| Show InChI InChI=1S/C26H29N3O2/c1-28(2)19-6-4-17-10-18-14-26(31)24-11-16-5-7-20(30)13-21(16)25(26,8-9-29(24)3)15-23(18)27-22(17)12-19/h4-7,10,12-13,24,30-31H,8-9,11,14-15H2,1-3H3/t24-,25-,26-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 67.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391598
(CHEMBL2147911)Show SMILES CN1CC[C@]23Cc4nc5c(C)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C25H26N2O2/c1-15-4-3-5-17-10-18-13-25(29)22-11-16-6-7-19(28)12-20(16)24(25,8-9-27(22)2)14-21(18)26-23(15)17/h3-7,10,12,22,28-29H,8-9,11,13-14H2,1-2H3/t22-,24-,25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 71.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391595
(CHEMBL2147908)Show SMILES CN1CC[C@]23Cc4nc5cccc(C)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C25H26N2O2/c1-15-4-3-5-21-19(15)10-17-13-25(29)23-11-16-6-7-18(28)12-20(16)24(25,8-9-27(23)2)14-22(17)26-21/h3-7,10,12,23,28-29H,8-9,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 71.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391605
(CHEMBL2147918)Show SMILES COc1ccc2cc3C[C@@]4(O)[C@H]5Cc6ccc(O)cc6[C@@]4(CCN5C)Cc3nc2c1 |r,THB:24:23:9:19.13.12| Show InChI InChI=1S/C25H26N2O3/c1-27-8-7-24-14-22-17(9-16-4-6-19(30-2)12-21(16)26-22)13-25(24,29)23(27)10-15-3-5-18(28)11-20(15)24/h3-6,9,11-12,23,28-29H,7-8,10,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 77.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391604
(CHEMBL2147917)Show SMILES COc1ccc2nc3C[C@]45CCN(C)[C@H](Cc6ccc(O)cc46)[C@]5(O)Cc3cc2c1 |r,TLB:13:12:23:22.16.15| Show InChI InChI=1S/C25H26N2O3/c1-27-8-7-24-14-22-17(9-16-10-19(30-2)5-6-21(16)26-22)13-25(24,29)23(27)11-15-3-4-18(28)12-20(15)24/h3-6,9-10,12,23,28-29H,7-8,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 77.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391603
(CHEMBL2147916)Show SMILES COc1cccc2nc3C[C@]45CCN(C)[C@H](Cc6ccc(O)cc46)[C@]5(O)Cc3cc12 |r,TLB:14:13:24:23.17.16| Show InChI InChI=1S/C25H26N2O3/c1-27-9-8-24-14-21-16(10-18-20(26-21)4-3-5-22(18)30-2)13-25(24,29)23(27)11-15-6-7-17(28)12-19(15)24/h3-7,10,12,23,28-29H,8-9,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 80.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391607
(CHEMBL2147920)Show SMILES CN1CC[C@]23Cc4nc5cccc(c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)C(F)(F)F |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C25H23F3N2O2/c1-30-8-7-23-13-21-15(9-17-18(25(26,27)28)3-2-4-20(17)29-21)12-24(23,32)22(30)10-14-5-6-16(31)11-19(14)23/h2-6,9,11,22,31-32H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 97.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391608
(CHEMBL2147921)Show SMILES CN1CC[C@]23Cc4nc5ccc(cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)C(F)(F)F |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C25H23F3N2O2/c1-30-7-6-23-13-21-16(8-15-9-17(25(26,27)28)3-5-20(15)29-21)12-24(23,32)22(30)10-14-2-4-18(31)11-19(14)23/h2-5,8-9,11,22,31-32H,6-7,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 97.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391590
(CHEMBL2147903)Show SMILES CN1CC[C@]23Cc4nc5c(Cl)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23ClN2O2/c1-27-8-7-23-13-20-16(9-15-3-2-4-19(25)22(15)26-20)12-24(23,29)21(27)10-14-5-6-17(28)11-18(14)23/h2-6,9,11,21,28-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 127 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391578
(CHEMBL2147923)Show SMILES CN1CC[C@]23Cc4nc5c(cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)C(F)(F)F |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C25H23F3N2O2/c1-30-8-7-23-13-20-16(9-15-3-2-4-18(22(15)29-20)25(26,27)28)12-24(23,32)21(30)10-14-5-6-17(31)11-19(14)23/h2-6,9,11,21,31-32H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 131 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391588
(CHEMBL2147901)Show SMILES CN1CC[C@]23Cc4nc5ccc(Cl)cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23ClN2O2/c1-27-7-6-23-13-21-16(8-15-9-17(25)3-5-20(15)26-21)12-24(23,29)22(27)10-14-2-4-18(28)11-19(14)23/h2-5,8-9,11,22,28-29H,6-7,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 132 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50391609
(CHEMBL2147922)Show SMILES CN1CC[C@]23Cc4nc5cc(ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)C(F)(F)F |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C25H23F3N2O2/c1-30-7-6-23-13-21-16(8-15-2-4-17(25(26,27)28)10-20(15)29-21)12-24(23,32)22(30)9-14-3-5-18(31)11-19(14)23/h2-5,8,10-11,22,31-32H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 153 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50329095
(CHEMBL1270282)Show SMILES CN1CC[C@]23Cc4nc5ccccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:17:21.27.20| Show InChI InChI=1S/C24H24N2O2/c1-26-9-8-23-14-21-17(10-16-4-2-3-5-20(16)25-21)13-24(23,28)22(26)11-15-6-7-18(27)12-19(15)23/h2-7,10,12,22,27-28H,8-9,11,13-14H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 153 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391594
(CHEMBL2147907)Show SMILES CN1CC[C@]23Cc4nc5c(F)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23FN2O2/c1-27-8-7-23-13-20-16(9-15-3-2-4-19(25)22(15)26-20)12-24(23,29)21(27)10-14-5-6-17(28)11-18(14)23/h2-6,9,11,21,28-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 154 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391582
(CHEMBL2147927)Show SMILES CN1CC[C@]23Cc4nc5c(cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)[N+]([O-])=O |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C24H23N3O4/c1-26-8-7-23-13-19-16(9-15-3-2-4-20(27(30)31)22(15)25-19)12-24(23,29)21(26)10-14-5-6-17(28)11-18(14)23/h2-6,9,11,21,28-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
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PC sid
UniChem
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PubMed
| 166 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391598
(CHEMBL2147911)Show SMILES CN1CC[C@]23Cc4nc5c(C)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C25H26N2O2/c1-15-4-3-5-17-10-18-13-25(29)22-11-16-6-7-19(28)12-20(16)24(25,8-9-27(22)2)14-21(18)26-23(15)17/h3-7,10,12,22,28-29H,8-9,11,13-14H2,1-2H3/t22-,24-,25-/m1/s1 | PDB
UniProtKB/SwissProt
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PC sid
UniChem
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| Article
PubMed
| 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391597
(CHEMBL2147910)Show SMILES CN1CC[C@]23Cc4nc5cc(C)ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C25H26N2O2/c1-15-3-4-17-10-18-13-25(29)23-11-16-5-6-19(28)12-20(16)24(25,7-8-27(23)2)14-22(18)26-21(17)9-15/h3-6,9-10,12,23,28-29H,7-8,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1 | PDB
UniProtKB/SwissProt
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PC sid
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PubMed
| 187 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391592
(CHEMBL2147905)Show SMILES CN1CC[C@]23Cc4nc5ccc(F)cc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23FN2O2/c1-27-7-6-23-13-21-16(8-15-9-17(25)3-5-20(15)26-21)12-24(23,29)22(27)10-14-2-4-18(28)11-19(14)23/h2-5,8-9,11,22,28-29H,6-7,10,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
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PubMed
| 196 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391583
(CHEMBL2147928)Show SMILES CN(C)c1cccc2nc3C[C@]45CCN(C)[C@H](Cc6ccc(O)cc46)[C@]5(O)Cc3cc12 |r,TLB:15:14:25:24.18.17| Show InChI InChI=1S/C26H29N3O2/c1-28(2)23-6-4-5-21-19(23)11-17-14-26(31)24-12-16-7-8-18(30)13-20(16)25(26,9-10-29(24)3)15-22(17)27-21/h4-8,11,13,24,30-31H,9-10,12,14-15H2,1-3H3/t24-,25-,26-/m1/s1 | PDB
UniProtKB/SwissProt
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PubMed
| 276 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391581
(CHEMBL2147926)Show SMILES CN1CC[C@]23Cc4nc5cc(ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)[N+]([O-])=O |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C24H23N3O4/c1-26-7-6-23-13-21-16(8-15-2-4-17(27(30)31)10-20(15)25-21)12-24(23,29)22(26)9-14-3-5-18(28)11-19(14)23/h2-5,8,10-11,22,28-29H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
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PC sid
UniChem
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| Article
PubMed
| 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391578
(CHEMBL2147923)Show SMILES CN1CC[C@]23Cc4nc5c(cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)C(F)(F)F |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C25H23F3N2O2/c1-30-8-7-23-13-20-16(9-15-3-2-4-18(22(15)29-20)25(26,27)28)12-24(23,32)21(30)10-14-5-6-17(31)11-19(14)23/h2-6,9,11,21,31-32H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
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PC sid
UniChem
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| Article
PubMed
| 338 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391586
(CHEMBL2147931)Show SMILES CN(C)c1cccc2cc3C[C@@]4(O)[C@H]5Cc6ccc(O)cc6[C@@]4(CCN5C)Cc3nc12 |r,THB:26:25:11:21.15.14| Show InChI InChI=1S/C26H29N3O2/c1-28(2)22-6-4-5-17-11-18-14-26(31)23-12-16-7-8-19(30)13-20(16)25(26,9-10-29(23)3)15-21(18)27-24(17)22/h4-8,11,13,23,30-31H,9-10,12,14-15H2,1-3H3/t23-,25-,26-/m1/s1 | PDB
UniProtKB/SwissProt
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PC sid
UniChem
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| Article
PubMed
| 343 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391584
(CHEMBL2147929)Show SMILES CN(C)c1ccc2nc3C[C@]45CCN(C)[C@H](Cc6ccc(O)cc46)[C@]5(O)Cc3cc2c1 |r,TLB:14:13:24:23.17.16| Show InChI InChI=1S/C26H29N3O2/c1-28(2)19-5-7-22-17(11-19)10-18-14-26(31)24-12-16-4-6-20(30)13-21(16)25(26,8-9-29(24)3)15-23(18)27-22/h4-7,10-11,13,24,30-31H,8-9,12,14-15H2,1-3H3/t24-,25-,26-/m1/s1 | PDB
UniProtKB/SwissProt
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PC sid
UniChem
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| Article
PubMed
| 349 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391585
(CHEMBL2147930)Show SMILES CN(C)c1ccc2cc3C[C@@]4(O)[C@H]5Cc6ccc(O)cc6[C@@]4(CCN5C)Cc3nc2c1 |r,THB:25:24:10:20.14.13| Show InChI InChI=1S/C26H29N3O2/c1-28(2)19-6-4-17-10-18-14-26(31)24-11-16-5-7-20(30)13-21(16)25(26,8-9-29(24)3)15-23(18)27-22(17)12-19/h4-7,10,12-13,24,30-31H,8-9,11,14-15H2,1-3H3/t24-,25-,26-/m1/s1 | PDB
UniProtKB/SwissProt
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UniChem
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PubMed
| 393 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391589
(CHEMBL2147902)Show SMILES CN1CC[C@]23Cc4nc5cc(Cl)ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23ClN2O2/c1-27-7-6-23-13-21-16(8-15-2-4-17(25)10-20(15)26-21)12-24(23,29)22(27)9-14-3-5-18(28)11-19(14)23/h2-5,8,10-11,22,28-29H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
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PubMed
| 394 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391593
(CHEMBL2147906)Show SMILES CN1CC[C@]23Cc4nc5cc(F)ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:18:28.22.21| Show InChI InChI=1S/C24H23FN2O2/c1-27-7-6-23-13-21-16(8-15-2-4-17(25)10-20(15)26-21)12-24(23,29)22(27)9-14-3-5-18(28)11-19(14)23/h2-5,8,10-11,22,28-29H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
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UniChem
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PubMed
| 412 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391609
(CHEMBL2147922)Show SMILES CN1CC[C@]23Cc4nc5cc(ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)C(F)(F)F |r,THB:0:1:17:27.21.20| Show InChI InChI=1S/C25H23F3N2O2/c1-30-7-6-23-13-21-16(8-15-2-4-17(25(26,27)28)10-20(15)29-21)12-24(23,32)22(30)9-14-3-5-18(31)11-19(14)23/h2-5,8,10-11,22,31-32H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1 | PDB
UniProtKB/SwissProt
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PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50391606
(CHEMBL2147919)Show SMILES COc1cccc2cc3C[C@@]4(O)[C@H]5Cc6ccc(O)cc6[C@@]4(CCN5C)Cc3nc12 |r,THB:25:24:10:20.14.13| Show InChI InChI=1S/C25H26N2O3/c1-27-9-8-24-14-20-17(10-16-4-3-5-21(30-2)23(16)26-20)13-25(24,29)22(27)11-15-6-7-18(28)12-19(15)24/h3-7,10,12,22,28-29H,8-9,11,13-14H2,1-2H3/t22-,24-,25-/m1/s1 | PDB
UniProtKB/SwissProt
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PubMed
| 1.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem 20: 5810-31 (2012)
Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5 |
More data for this
Ligand-Target Pair | |
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