Found 62 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397390
(CHEMBL2170545)Show SMILES CCCCCn1cc(C(=O)NC2C3CC4CC(C3)CC2C4)c(=O)cc1C |TLB:20:19:17:13.14.15,THB:20:14:11.19.18:17,15:14:11:18.16.17,15:16:11:13.20.14,10:11:17:13.14.15,(25.24,-38.56,;26.58,-39.34,;27.92,-38.57,;29.25,-39.35,;30.6,-38.58,;31.93,-39.36,;33.27,-38.58,;34.61,-39.36,;35.95,-38.59,;35.95,-37.05,;37.29,-39.37,;38.73,-38.65,;39.88,-37.52,;41.08,-38.03,;42.39,-37.76,;42.46,-36.35,;41.19,-35.76,;39.93,-36.15,;40.18,-36.86,;40.13,-38.32,;41.4,-38.9,;34.61,-40.91,;35.94,-41.68,;33.26,-41.67,;31.93,-40.9,;30.59,-41.67,)| Show InChI InChI=1S/C22H32N2O2/c1-3-4-5-6-24-13-19(20(25)7-14(24)2)22(26)23-21-17-9-15-8-16(11-17)12-18(21)10-15/h7,13,15-18,21H,3-6,8-12H2,1-2H3,(H,23,26) | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| 0.260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397387
(CHEMBL2170532)Show SMILES Cc1cc(=O)c(cn1CCCC(F)(F)F)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:17:18:21:25.24.23,THB:19:20:23:27.18.26,19:18:21.20.25:23,26:18:21:25.24.23,26:24:21:27.19.18| Show InChI InChI=1S/C21H27F3N2O2/c1-13-5-18(27)17(12-26(13)4-2-3-21(22,23)24)19(28)25-20-9-14-6-15(10-20)8-16(7-14)11-20/h5,12,14-16H,2-4,6-11H2,1H3,(H,25,28) | PDB
Reactome pathway
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| Article
PubMed
| 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM21281
((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23 |r| Show InChI InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1 | PDB
Reactome pathway
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| PDB
Article
PubMed
| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397391
(CHEMBL2170544)Show SMILES CCCCCn1cc(C(=O)NC(C)C23CC4CC(CC(C4)C2)C3)c(=O)cc1C |TLB:16:17:14.15.20:21,THB:16:15:21:22.17.18,18:17:14:20.19.21,18:19:14:22.16.17| Show InChI InChI=1S/C24H36N2O2/c1-4-5-6-7-26-15-21(22(27)8-16(26)2)23(28)25-17(3)24-12-18-9-19(13-24)11-20(10-18)14-24/h8,15,17-20H,4-7,9-14H2,1-3H3,(H,25,28) | PDB
Reactome pathway
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PubMed
| 6.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397396
(CHEMBL2170550)Show SMILES CCCCCn1cc(C(=O)NC(C)C23CC4CC(CC(C4)C2)C3)c(=O)cc1C(C)(C)C |TLB:16:17:14.15.20:21,THB:16:15:21:22.17.18,18:17:14:20.19.21,18:19:14:22.16.17| Show InChI InChI=1S/C27H42N2O2/c1-6-7-8-9-29-17-22(23(30)13-24(29)26(3,4)5)25(31)28-18(2)27-14-19-10-20(15-27)12-21(11-19)16-27/h13,17-21H,6-12,14-16H2,1-5H3,(H,28,31) | PDB
Reactome pathway
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397393
(CHEMBL2170547)Show InChI InChI=1S/C21H28N2O2/c1-5-6-10-13-23-15-17(18(24)14-19(23)21(2,3)4)20(25)22-16-11-8-7-9-12-16/h7-9,11-12,14-15H,5-6,10,13H2,1-4H3,(H,22,25) | PDB
Reactome pathway
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| CHEMBL
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UniChem
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PubMed
| 9.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397395
(CHEMBL2170549)Show SMILES CCCCCn1cc(C(=O)NC2C3CC4CC(C3)CC2C4)c(=O)cc1C(C)(C)C |TLB:20:19:17:13.14.15,THB:10:11:17:13.14.15,20:14:11.19.18:17,15:14:11:18.16.17,15:16:11:13.20.14,(4.03,-16.9,;5.37,-17.68,;6.72,-16.91,;8.05,-17.69,;9.39,-16.91,;10.72,-17.69,;12.07,-16.92,;13.41,-17.7,;14.74,-16.93,;14.75,-15.38,;16.08,-17.71,;17.52,-16.99,;18.67,-15.86,;19.88,-16.36,;21.18,-16.1,;21.25,-14.69,;19.98,-14.1,;18.72,-14.49,;18.98,-15.2,;18.92,-16.66,;20.19,-17.24,;13.4,-19.24,;14.74,-20.02,;12.06,-20.01,;10.72,-19.24,;9.38,-20,;9.38,-21.54,;8.05,-19.23,;8.04,-20.77,)| Show InChI InChI=1S/C25H38N2O2/c1-5-6-7-8-27-15-20(21(28)14-22(27)25(2,3)4)24(29)26-23-18-10-16-9-17(12-18)13-19(23)11-16/h14-19,23H,5-13H2,1-4H3,(H,26,29) | PDB
Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397397
(CHEMBL2170551)Show SMILES CCCCCn1cc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c(=O)cc1C(C)(C)C |TLB:15:16:13.14.19:20,THB:15:14:20:21.16.17,17:16:13:19.18.20,17:18:13:21.15.16| Show InChI InChI=1S/C26H40N2O2/c1-5-6-7-8-28-16-21(22(29)12-23(28)25(2,3)4)24(30)27-17-26-13-18-9-19(14-26)11-20(10-18)15-26/h12,16,18-20H,5-11,13-15,17H2,1-4H3,(H,27,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 10.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397383
(CHEMBL2170526)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(C2CC2)c1C |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C25H36N2O2/c1-3-4-5-8-27-15-21(23(28)22(16(27)2)20-6-7-20)24(29)26-25-12-17-9-18(13-25)11-19(10-17)14-25/h15,17-20H,3-14H2,1-2H3,(H,26,29) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 13.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397394
(CHEMBL2170548)Show InChI InChI=1S/C19H30N2O2/c1-5-6-7-10-21-13-15(18(23)20-12-14-8-9-14)16(22)11-17(21)19(2,3)4/h11,13-14H,5-10,12H2,1-4H3,(H,20,23) | PDB
Reactome pathway
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Similars
| Article
PubMed
| 14.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397392
(CHEMBL2170546)Show SMILES CCCCCn1cc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c(=O)cc1C |TLB:15:16:13.14.19:20,THB:15:14:20:21.16.17,17:16:13:19.18.20,17:18:13:21.15.16| Show InChI InChI=1S/C23H34N2O2/c1-3-4-5-6-25-14-20(21(26)7-16(25)2)22(27)24-15-23-11-17-8-18(12-23)10-19(9-17)13-23/h7,14,17-19H,3-6,8-13,15H2,1-2H3,(H,24,27) | PDB
Reactome pathway
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| CHEMBL
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UniChem
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| Article
PubMed
| 15.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397386
(CHEMBL2170530)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(I)c1C |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C22H31IN2O2/c1-3-4-5-6-25-13-18(20(26)19(23)14(25)2)21(27)24-22-10-15-7-16(11-22)9-17(8-15)12-22/h13,15-17H,3-12H2,1-2H3,(H,24,27) | PDB
Reactome pathway
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PC sid
UniChem
Similars
| Article
PubMed
| 20.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397388
(CHEMBL2170534)Show SMILES Cc1cc(=O)c(cn1CC1CCOCC1)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:17:18:21:25.24.23,THB:19:20:23:27.18.26,19:18:21.20.25:23,26:18:21:25.24.23,26:24:21:27.19.18| Show InChI InChI=1S/C23H32N2O3/c1-15-6-21(26)20(14-25(15)13-16-2-4-28-5-3-16)22(27)24-23-10-17-7-18(11-23)9-19(8-17)12-23/h6,14,16-19H,2-5,7-13H2,1H3,(H,24,27) | PDB
Reactome pathway
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PC sid
UniChem
Similars
| Article
PubMed
| 24.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397389
(CHEMBL2170542)Show InChI InChI=1S/C18H28N2O2/c1-3-4-8-11-20-13-16(17(21)12-14(20)2)18(22)19-15-9-6-5-7-10-15/h12-13,15H,3-11H2,1-2H3,(H,19,22) | PDB
Reactome pathway
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UniChem
Similars
| Article
PubMed
| 24.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397385
(CHEMBL2170529)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(-c2ccncc2)c1C |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C27H35N3O2/c1-3-4-5-10-30-17-23(25(31)24(18(30)2)22-6-8-28-9-7-22)26(32)29-27-14-19-11-20(15-27)13-21(12-19)16-27/h6-9,17,19-21H,3-5,10-16H2,1-2H3,(H,29,32) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 36.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM21281
((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23 |r| Show InChI InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1 | PDB
NCI pathway
Reactome pathway
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| Purchase
CHEMBL
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| Article
PubMed
| 52.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397384
(CHEMBL2170528)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(c1C)-c1ccc(CC)cc1 |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C30H40N2O2/c1-4-6-7-12-32-19-26(28(33)27(20(32)3)25-10-8-21(5-2)9-11-25)29(34)31-30-16-22-13-23(17-30)15-24(14-22)18-30/h8-11,19,22-24H,4-7,12-18H2,1-3H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 54.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50397393
(CHEMBL2170547)Show InChI InChI=1S/C21H28N2O2/c1-5-6-10-13-23-15-17(18(24)14-19(23)21(2,3)4)20(25)22-16-11-8-7-9-12-16/h7-9,11-12,14-15H,5-6,10,13H2,1-4H3,(H,22,25) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 87.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50397383
(CHEMBL2170526)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(C2CC2)c1C |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C25H36N2O2/c1-3-4-5-8-27-15-21(23(28)22(16(27)2)20-6-7-20)24(29)26-25-12-17-9-18(13-25)11-19(10-17)14-25/h15,17-20H,3-14H2,1-2H3,(H,26,29) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 105 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50397394
(CHEMBL2170548)Show InChI InChI=1S/C19H30N2O2/c1-5-6-7-10-21-13-15(18(23)20-12-14-8-9-14)16(22)11-17(21)19(2,3)4/h11,13-14H,5-10,12H2,1-4H3,(H,20,23) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 176 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397400
(CHEMBL2170525)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(c1C)-c1ccccc1 |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C28H36N2O2/c1-3-4-8-11-30-18-24(26(31)25(19(30)2)23-9-6-5-7-10-23)27(32)29-28-15-20-12-21(16-28)14-22(13-20)17-28/h5-7,9-10,18,20-22H,3-4,8,11-17H2,1-2H3,(H,29,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 189 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50397386
(CHEMBL2170530)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(I)c1C |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C22H31IN2O2/c1-3-4-5-6-25-13-18(20(26)19(23)14(25)2)21(27)24-22-10-15-7-16(11-22)9-17(8-15)12-22/h13,15-17H,3-12H2,1-2H3,(H,24,27) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 193 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397403
(CHEMBL2170533)Show SMILES Cc1cc(=O)c(cn1CCC1CCOCC1)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:18:19:22:26.25.24,THB:20:21:24:28.19.27,20:19:22.21.26:24,27:19:22:26.25.24,27:25:22:28.20.19| Show InChI InChI=1S/C24H34N2O3/c1-16-8-22(27)21(15-26(16)5-2-17-3-6-29-7-4-17)23(28)25-24-12-18-9-19(13-24)11-20(10-18)14-24/h8,15,17-20H,2-7,9-14H2,1H3,(H,25,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 196 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50397396
(CHEMBL2170550)Show SMILES CCCCCn1cc(C(=O)NC(C)C23CC4CC(CC(C4)C2)C3)c(=O)cc1C(C)(C)C |TLB:16:17:14.15.20:21,THB:16:15:21:22.17.18,18:17:14:20.19.21,18:19:14:22.16.17| Show InChI InChI=1S/C27H42N2O2/c1-6-7-8-9-29-17-22(23(30)13-24(29)26(3,4)5)25(31)28-18(2)27-14-19-10-20(15-27)12-21(11-19)16-27/h13,17-21H,6-12,14-16H2,1-5H3,(H,28,31) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 548 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50397395
(CHEMBL2170549)Show SMILES CCCCCn1cc(C(=O)NC2C3CC4CC(C3)CC2C4)c(=O)cc1C(C)(C)C |TLB:20:19:17:13.14.15,THB:10:11:17:13.14.15,20:14:11.19.18:17,15:14:11:18.16.17,15:16:11:13.20.14,(4.03,-16.9,;5.37,-17.68,;6.72,-16.91,;8.05,-17.69,;9.39,-16.91,;10.72,-17.69,;12.07,-16.92,;13.41,-17.7,;14.74,-16.93,;14.75,-15.38,;16.08,-17.71,;17.52,-16.99,;18.67,-15.86,;19.88,-16.36,;21.18,-16.1,;21.25,-14.69,;19.98,-14.1,;18.72,-14.49,;18.98,-15.2,;18.92,-16.66,;20.19,-17.24,;13.4,-19.24,;14.74,-20.02,;12.06,-20.01,;10.72,-19.24,;9.38,-20,;9.38,-21.54,;8.05,-19.23,;8.04,-20.77,)| Show InChI InChI=1S/C25H38N2O2/c1-5-6-7-8-27-15-20(21(28)14-22(27)25(2,3)4)24(29)26-23-18-10-16-9-17(12-18)13-19(23)11-16/h14-19,23H,5-13H2,1-4H3,(H,26,29) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 562 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397408
(CHEMBL2170540)Show InChI InChI=1S/C18H22N2O2/c1-3-4-8-11-20-13-16(17(21)12-14(20)2)18(22)19-15-9-6-5-7-10-15/h5-7,9-10,12-13H,3-4,8,11H2,1-2H3,(H,19,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50397392
(CHEMBL2170546)Show SMILES CCCCCn1cc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c(=O)cc1C |TLB:15:16:13.14.19:20,THB:15:14:20:21.16.17,17:16:13:19.18.20,17:18:13:21.15.16| Show InChI InChI=1S/C23H34N2O2/c1-3-4-5-6-25-14-20(21(26)7-16(25)2)22(27)24-15-23-11-17-8-18(12-23)10-19(9-17)13-23/h7,14,17-19H,3-6,8-13,15H2,1-2H3,(H,24,27) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397398
(CHEMBL2170523)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(c1C)-c1cccc(c1)C#N |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C29H35N3O2/c1-3-4-5-9-32-18-25(27(33)26(19(32)2)24-8-6-7-20(13-24)17-30)28(34)31-29-14-21-10-22(15-29)12-23(11-21)16-29/h6-8,13,18,21-23H,3-5,9-12,14-16H2,1-2H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397401
(CHEMBL2170527)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(c1C)-c1cccc(c1)C(C)=O |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C30H38N2O3/c1-4-5-6-10-32-18-26(28(34)27(19(32)2)25-9-7-8-24(14-25)20(3)33)29(35)31-30-15-21-11-22(16-30)13-23(12-21)17-30/h7-9,14,18,21-23H,4-6,10-13,15-17H2,1-3H3,(H,31,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50397385
(CHEMBL2170529)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(-c2ccncc2)c1C |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C27H35N3O2/c1-3-4-5-10-30-17-23(25(31)24(18(30)2)22-6-8-28-9-7-22)26(32)29-27-14-19-11-20(15-27)13-21(12-19)16-27/h6-9,17,19-21H,3-5,10-16H2,1-2H3,(H,29,32) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50397390
(CHEMBL2170545)Show SMILES CCCCCn1cc(C(=O)NC2C3CC4CC(C3)CC2C4)c(=O)cc1C |TLB:20:19:17:13.14.15,THB:20:14:11.19.18:17,15:14:11:18.16.17,15:16:11:13.20.14,10:11:17:13.14.15,(25.24,-38.56,;26.58,-39.34,;27.92,-38.57,;29.25,-39.35,;30.6,-38.58,;31.93,-39.36,;33.27,-38.58,;34.61,-39.36,;35.95,-38.59,;35.95,-37.05,;37.29,-39.37,;38.73,-38.65,;39.88,-37.52,;41.08,-38.03,;42.39,-37.76,;42.46,-36.35,;41.19,-35.76,;39.93,-36.15,;40.18,-36.86,;40.13,-38.32,;41.4,-38.9,;34.61,-40.91,;35.94,-41.68,;33.26,-41.67,;31.93,-40.9,;30.59,-41.67,)| Show InChI InChI=1S/C22H32N2O2/c1-3-4-5-6-24-13-19(20(25)7-14(24)2)22(26)23-21-17-9-15-8-16(11-17)12-18(21)10-15/h7,13,15-18,21H,3-6,8-12H2,1-2H3,(H,23,26) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397399
(CHEMBL2170524)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(c1C)-c1ccc(C)cc1 |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C29H38N2O2/c1-4-5-6-11-31-18-25(27(32)26(20(31)3)24-9-7-19(2)8-10-24)28(33)30-29-15-21-12-22(16-29)14-23(13-21)17-29/h7-10,18,21-23H,4-6,11-17H2,1-3H3,(H,30,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397411
(CHEMBL2170543)Show InChI InChI=1S/C16H24N2O2/c1-3-4-5-8-18-11-14(15(19)9-12(18)2)16(20)17-10-13-6-7-13/h9,11,13H,3-8,10H2,1-2H3,(H,17,20) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397410
(CHEMBL2170541)Show InChI InChI=1S/C17H27N3O2/c1-3-4-6-9-19-13-15(16(21)12-14(19)2)17(22)18-20-10-7-5-8-11-20/h12-13H,3-11H2,1-2H3,(H,18,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397409
(CHEMBL2170539)Show InChI InChI=1S/C15H24N2O2/c1-5-6-7-8-17-10-13(14(18)9-12(17)4)15(19)16-11(2)3/h9-11H,5-8H2,1-4H3,(H,16,19) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397407
(CHEMBL2170538)Show SMILES C\C=C/n1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1C |TLB:8:9:12:16.15.14,THB:10:11:14:18.9.17,10:9:12.11.16:14,17:9:12:16.15.14,17:15:12:18.10.9| Show InChI InChI=1S/C20H26N2O2/c1-3-4-22-12-17(18(23)5-13(22)2)19(24)21-20-9-14-6-15(10-20)8-16(7-14)11-20/h3-5,12,14-16H,6-11H2,1-2H3,(H,21,24)/b4-3- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397404
(CHEMBL2170535)Show SMILES Cc1cc(=O)c(cn1CCC1OCCO1)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:17:18:21:25.24.23,THB:19:20:23:27.18.26,19:18:21.20.25:23,26:18:21:25.24.23,26:24:21:27.19.18| Show InChI InChI=1S/C22H30N2O4/c1-14-6-19(25)18(13-24(14)3-2-20-27-4-5-28-20)21(26)23-22-10-15-7-16(11-22)9-17(8-15)12-22/h6,13,15-17,20H,2-5,7-12H2,1H3,(H,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50397387
(CHEMBL2170532)Show SMILES Cc1cc(=O)c(cn1CCCC(F)(F)F)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:17:18:21:25.24.23,THB:19:20:23:27.18.26,19:18:21.20.25:23,26:18:21:25.24.23,26:24:21:27.19.18| Show InChI InChI=1S/C21H27F3N2O2/c1-13-5-18(27)17(12-26(13)4-2-3-21(22,23)24)19(28)25-20-9-14-6-15(10-20)8-16(7-14)11-20/h5,12,14-16H,2-4,6-11H2,1H3,(H,25,28) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50397397
(CHEMBL2170551)Show SMILES CCCCCn1cc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c(=O)cc1C(C)(C)C |TLB:15:16:13.14.19:20,THB:15:14:20:21.16.17,17:16:13:19.18.20,17:18:13:21.15.16| Show InChI InChI=1S/C26H40N2O2/c1-5-6-7-8-28-16-21(22(29)12-23(28)25(2,3)4)24(30)27-17-26-13-18-9-19(14-26)11-20(10-18)15-26/h12,16,18-20H,5-11,13-15,17H2,1-4H3,(H,27,30) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50397388
(CHEMBL2170534)Show SMILES Cc1cc(=O)c(cn1CC1CCOCC1)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:17:18:21:25.24.23,THB:19:20:23:27.18.26,19:18:21.20.25:23,26:18:21:25.24.23,26:24:21:27.19.18| Show InChI InChI=1S/C23H32N2O3/c1-15-6-21(26)20(14-25(15)13-16-2-4-28-5-3-16)22(27)24-23-10-17-7-18(11-23)9-19(8-17)12-23/h6,14,16-19H,2-5,7-13H2,1H3,(H,24,27) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50397384
(CHEMBL2170528)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(c1C)-c1ccc(CC)cc1 |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C30H40N2O2/c1-4-6-7-12-32-19-26(28(33)27(20(32)3)25-10-8-21(5-2)9-11-25)29(34)31-30-16-22-13-23(17-30)15-24(14-22)18-30/h8-11,19,22-24H,4-7,12-18H2,1-3H3,(H,31,34) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397402
(CHEMBL2170531)Show SMILES COCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1C |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C21H30N2O3/c1-14-6-19(24)18(13-23(14)4-3-5-26-2)20(25)22-21-10-15-7-16(11-21)9-17(8-15)12-21/h6,13,15-17H,3-5,7-12H2,1-2H3,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50397389
(CHEMBL2170542)Show InChI InChI=1S/C18H28N2O2/c1-3-4-8-11-20-13-16(17(21)12-14(20)2)18(22)19-15-9-6-5-7-10-15/h12-13,15H,3-11H2,1-2H3,(H,19,22) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397405
(CHEMBL2170536)Show SMILES Cc1cc(=O)c(cn1CC1OCCO1)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:16:17:20:24.23.22,THB:18:19:22:26.17.25,18:17:20.19.24:22,25:17:20:24.23.22,25:23:20:26.18.17| Show InChI InChI=1S/C21H28N2O4/c1-13-4-18(24)17(11-23(13)12-19-26-2-3-27-19)20(25)22-21-8-14-5-15(9-21)7-16(6-14)10-21/h4,11,14-16,19H,2-3,5-10,12H2,1H3,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50397391
(CHEMBL2170544)Show SMILES CCCCCn1cc(C(=O)NC(C)C23CC4CC(CC(C4)C2)C3)c(=O)cc1C |TLB:16:17:14.15.20:21,THB:16:15:21:22.17.18,18:17:14:20.19.21,18:19:14:22.16.17| Show InChI InChI=1S/C24H36N2O2/c1-4-5-6-7-26-15-21(22(27)8-16(26)2)23(28)25-17(3)24-12-18-9-19(13-24)11-20(10-18)14-24/h8,15,17-20H,4-7,9-14H2,1-3H3,(H,25,28) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397406
(CHEMBL2170537)Show SMILES COC(Cn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1C)OC |TLB:9:10:13:17.16.15,THB:11:12:15:19.10.18,11:10:13.12.17:15,18:10:13:17.16.15,18:16:13:19.11.10| Show InChI InChI=1S/C21H30N2O4/c1-13-4-18(24)17(11-23(13)12-19(26-2)27-3)20(25)22-21-8-14-5-15(9-21)7-16(6-14)10-21/h4,11,14-16,19H,5-10,12H2,1-3H3,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation counting |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397389
(CHEMBL2170542)Show InChI InChI=1S/C18H28N2O2/c1-3-4-8-11-20-13-16(17(21)12-14(20)2)18(22)19-15-9-6-5-7-10-15/h12-13,15H,3-11H2,1-2H3,(H,19,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 49.9 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397390
(CHEMBL2170545)Show SMILES CCCCCn1cc(C(=O)NC2C3CC4CC(C3)CC2C4)c(=O)cc1C |TLB:20:19:17:13.14.15,THB:20:14:11.19.18:17,15:14:11:18.16.17,15:16:11:13.20.14,10:11:17:13.14.15,(25.24,-38.56,;26.58,-39.34,;27.92,-38.57,;29.25,-39.35,;30.6,-38.58,;31.93,-39.36,;33.27,-38.58,;34.61,-39.36,;35.95,-38.59,;35.95,-37.05,;37.29,-39.37,;38.73,-38.65,;39.88,-37.52,;41.08,-38.03,;42.39,-37.76,;42.46,-36.35,;41.19,-35.76,;39.93,-36.15,;40.18,-36.86,;40.13,-38.32,;41.4,-38.9,;34.61,-40.91,;35.94,-41.68,;33.26,-41.67,;31.93,-40.9,;30.59,-41.67,)| Show InChI InChI=1S/C22H32N2O2/c1-3-4-5-6-24-13-19(20(25)7-14(24)2)22(26)23-21-17-9-15-8-16(11-17)12-18(21)10-15/h7,13,15-18,21H,3-6,8-12H2,1-2H3,(H,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 38.4 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397396
(CHEMBL2170550)Show SMILES CCCCCn1cc(C(=O)NC(C)C23CC4CC(CC(C4)C2)C3)c(=O)cc1C(C)(C)C |TLB:16:17:14.15.20:21,THB:16:15:21:22.17.18,18:17:14:20.19.21,18:19:14:22.16.17| Show InChI InChI=1S/C27H42N2O2/c1-6-7-8-9-29-17-22(23(30)13-24(29)26(3,4)5)25(31)28-18(2)27-14-19-10-20(15-27)12-21(11-19)16-27/h13,17-21H,6-12,14-16H2,1-5H3,(H,28,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 47.1 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397392
(CHEMBL2170546)Show SMILES CCCCCn1cc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c(=O)cc1C |TLB:15:16:13.14.19:20,THB:15:14:20:21.16.17,17:16:13:19.18.20,17:18:13:21.15.16| Show InChI InChI=1S/C23H34N2O2/c1-3-4-5-6-25-14-20(21(26)7-16(25)2)22(27)24-15-23-11-17-8-18(12-23)10-19(9-17)13-23/h7,14,17-19H,3-6,8-13,15H2,1-2H3,(H,24,27) | PDB
Reactome pathway
KEGG
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UniProtKB/TrEMBL
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 53.1 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397387
(CHEMBL2170532)Show SMILES Cc1cc(=O)c(cn1CCCC(F)(F)F)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:17:18:21:25.24.23,THB:19:20:23:27.18.26,19:18:21.20.25:23,26:18:21:25.24.23,26:24:21:27.19.18| Show InChI InChI=1S/C21H27F3N2O2/c1-13-5-18(27)17(12-26(13)4-2-3-21(22,23)24)19(28)25-20-9-14-6-15(10-20)8-16(7-14)11-20/h5,12,14-16H,2-4,6-11H2,1H3,(H,25,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
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antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 17.3 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397384
(CHEMBL2170528)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(c1C)-c1ccc(CC)cc1 |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C30H40N2O2/c1-4-6-7-12-32-19-26(28(33)27(20(32)3)25-10-8-21(5-2)9-11-25)29(34)31-30-16-22-13-23(17-30)15-24(14-22)18-30/h8-11,19,22-24H,4-7,12-18H2,1-3H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 39.9 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397397
(CHEMBL2170551)Show SMILES CCCCCn1cc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c(=O)cc1C(C)(C)C |TLB:15:16:13.14.19:20,THB:15:14:20:21.16.17,17:16:13:19.18.20,17:18:13:21.15.16| Show InChI InChI=1S/C26H40N2O2/c1-5-6-7-8-28-16-21(22(29)12-23(28)25(2,3)4)24(30)27-17-26-13-18-9-19(14-26)11-20(10-18)15-26/h12,16,18-20H,5-11,13-15,17H2,1-4H3,(H,27,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 49.2 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397395
(CHEMBL2170549)Show SMILES CCCCCn1cc(C(=O)NC2C3CC4CC(C3)CC2C4)c(=O)cc1C(C)(C)C |TLB:20:19:17:13.14.15,THB:10:11:17:13.14.15,20:14:11.19.18:17,15:14:11:18.16.17,15:16:11:13.20.14,(4.03,-16.9,;5.37,-17.68,;6.72,-16.91,;8.05,-17.69,;9.39,-16.91,;10.72,-17.69,;12.07,-16.92,;13.41,-17.7,;14.74,-16.93,;14.75,-15.38,;16.08,-17.71,;17.52,-16.99,;18.67,-15.86,;19.88,-16.36,;21.18,-16.1,;21.25,-14.69,;19.98,-14.1,;18.72,-14.49,;18.98,-15.2,;18.92,-16.66,;20.19,-17.24,;13.4,-19.24,;14.74,-20.02,;12.06,-20.01,;10.72,-19.24,;9.38,-20,;9.38,-21.54,;8.05,-19.23,;8.04,-20.77,)| Show InChI InChI=1S/C25H38N2O2/c1-5-6-7-8-27-15-20(21(28)14-22(27)25(2,3)4)24(29)26-23-18-10-16-9-17(12-18)13-19(23)11-16/h14-19,23H,5-13H2,1-4H3,(H,26,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 452 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397391
(CHEMBL2170544)Show SMILES CCCCCn1cc(C(=O)NC(C)C23CC4CC(CC(C4)C2)C3)c(=O)cc1C |TLB:16:17:14.15.20:21,THB:16:15:21:22.17.18,18:17:14:20.19.21,18:19:14:22.16.17| Show InChI InChI=1S/C24H36N2O2/c1-4-5-6-7-26-15-21(22(27)8-16(26)2)23(28)25-17(3)24-12-18-9-19(13-24)11-20(10-18)14-24/h8,15,17-20H,4-7,9-14H2,1-3H3,(H,25,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
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antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 84.2 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397386
(CHEMBL2170530)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(I)c1C |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C22H31IN2O2/c1-3-4-5-6-25-13-18(20(26)19(23)14(25)2)21(27)24-22-10-15-7-16(11-22)9-17(8-15)12-22/h13,15-17H,3-12H2,1-2H3,(H,24,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 11.9 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397383
(CHEMBL2170526)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(C2CC2)c1C |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C25H36N2O2/c1-3-4-5-8-27-15-21(23(28)22(16(27)2)20-6-7-20)24(29)26-25-12-17-9-18(13-25)11-19(10-17)14-25/h15,17-20H,3-14H2,1-2H3,(H,26,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 88.5 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397385
(CHEMBL2170529)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(-c2ccncc2)c1C |TLB:10:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C27H35N3O2/c1-3-4-5-10-30-17-23(25(31)24(18(30)2)22-6-8-28-9-7-22)26(32)29-27-14-19-11-20(15-27)13-21(12-19)16-27/h6-9,17,19-21H,3-5,10-16H2,1-2H3,(H,29,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 114 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397388
(CHEMBL2170534)Show SMILES Cc1cc(=O)c(cn1CC1CCOCC1)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:17:18:21:25.24.23,THB:19:20:23:27.18.26,19:18:21.20.25:23,26:18:21:25.24.23,26:24:21:27.19.18| Show InChI InChI=1S/C23H32N2O3/c1-15-6-21(26)20(14-25(15)13-16-2-4-28-5-3-16)22(27)24-23-10-17-7-18(11-23)9-19(8-17)12-23/h6,14,16-19H,2-5,7-13H2,1H3,(H,24,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 47.4 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM21281
((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23 |r| Show InChI InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
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| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | n/a | n/a | 89.6 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397393
(CHEMBL2170547)Show InChI InChI=1S/C21H28N2O2/c1-5-6-10-13-23-15-17(18(24)14-19(23)21(2,3)4)20(25)22-16-11-8-7-9-12-16/h7-9,11-12,14-15H,5-6,10,13H2,1-4H3,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50397394
(CHEMBL2170548)Show InChI InChI=1S/C19H30N2O2/c1-5-6-7-10-21-13-15(18(23)20-12-14-8-9-14)16(22)11-17(21)19(2,3)4/h11,13-14H,5-10,12H2,1-4H3,(H,20,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 27.8 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells membrane by [35S]-GTPgammaS assay |
J Med Chem 55: 8948-52 (2012)
Article DOI: 10.1021/jm3008568
BindingDB Entry DOI: 10.7270/Q27H1KQS |
More data for this
Ligand-Target Pair | |
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