Found 24 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM17638
(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immuno assay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50029593
(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)Show InChI InChI=1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant COX2 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immunoassay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50391125
(CHEMBL2087943)Show SMILES Cc1ccc(cc1)C1SCC(=O)N1Nc1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C17H18N2O3S2/c1-12-3-5-13(6-4-12)17-19(16(20)11-23-17)18-14-7-9-15(10-8-14)24(2,21)22/h3-10,17-18H,11H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.44E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant COX2 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immunoassay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM17638
(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
PDB
Article
PubMed
| n/a | n/a | 1.83E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant COX2 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immunoassay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50391128
(CHEMBL2087940)Show InChI InChI=1S/C16H16N2O3S2/c1-23(20,21)14-9-7-13(8-10-14)17-18-15(19)11-22-16(18)12-5-3-2-4-6-12/h2-10,16-17H,11H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant COX2 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immunoassay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50391130
(CHEMBL2087938)Show SMILES Cc1ccc(cc1)C1SCC(=O)N1Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H17N3O3S2/c1-11-2-4-12(5-3-11)16-19(15(20)10-23-16)18-13-6-8-14(9-7-13)24(17,21)22/h2-9,16,18H,10H2,1H3,(H2,17,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant COX2 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immunoassay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50391126
(CHEMBL2087944)Show SMILES CS(=O)(=O)c1ccc(NN2C(SCC2=O)c2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C17H15F3N2O3S2/c1-27(24,25)14-8-6-13(7-9-14)21-22-15(23)10-26-16(22)11-2-4-12(5-3-11)17(18,19)20/h2-9,16,21H,10H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant COX2 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immunoassay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50391132
(CHEMBL2087936)Show SMILES NS(=O)(=O)c1ccc(NN2C(SCC2=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C15H14ClN3O3S2/c16-11-3-1-10(2-4-11)15-19(14(20)9-23-15)18-12-5-7-13(8-6-12)24(17,21)22/h1-8,15,18H,9H2,(H2,17,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.89E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immuno assay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50391131
(CHEMBL2087937)Show SMILES NS(=O)(=O)c1ccc(NN2C(SCC2=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C15H14FN3O3S2/c16-11-3-1-10(2-4-11)15-19(14(20)9-23-15)18-12-5-7-13(8-6-12)24(17,21)22/h1-8,15,18H,9H2,(H2,17,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immuno assay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50391134
(CHEMBL2087942)Show SMILES CS(=O)(=O)c1ccc(NN2C(SCC2=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C16H15FN2O3S2/c1-24(21,22)14-8-6-13(7-9-14)18-19-15(20)10-23-16(19)11-2-4-12(17)5-3-11/h2-9,16,18H,10H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant COX2 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immunoassay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50391132
(CHEMBL2087936)Show SMILES NS(=O)(=O)c1ccc(NN2C(SCC2=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C15H14ClN3O3S2/c16-11-3-1-10(2-4-11)15-19(14(20)9-23-15)18-12-5-7-13(8-6-12)24(17,21)22/h1-8,15,18H,9H2,(H2,17,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant COX2 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immunoassay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50391129
(CHEMBL2087939)Show SMILES NS(=O)(=O)c1ccc(NN2C(SCC2=O)c2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C16H14F3N3O3S2/c17-16(18,19)11-3-1-10(2-4-11)15-22(14(23)9-26-15)21-12-5-7-13(8-6-12)27(20,24)25/h1-8,15,21H,9H2,(H2,20,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant COX2 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immunoassay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50391129
(CHEMBL2087939)Show SMILES NS(=O)(=O)c1ccc(NN2C(SCC2=O)c2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C16H14F3N3O3S2/c17-16(18,19)11-3-1-10(2-4-11)15-22(14(23)9-26-15)21-12-5-7-13(8-6-12)27(20,24)25/h1-8,15,21H,9H2,(H2,20,24,25) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immuno assay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50391126
(CHEMBL2087944)Show SMILES CS(=O)(=O)c1ccc(NN2C(SCC2=O)c2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C17H15F3N2O3S2/c1-27(24,25)14-8-6-13(7-9-14)21-22-15(23)10-26-16(22)11-2-4-12(5-3-11)17(18,19)20/h2-9,16,21H,10H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immuno assay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50391134
(CHEMBL2087942)Show SMILES CS(=O)(=O)c1ccc(NN2C(SCC2=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C16H15FN2O3S2/c1-24(21,22)14-8-6-13(7-9-14)18-19-15(20)10-23-16(19)11-2-4-12(17)5-3-11/h2-9,16,18H,10H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immuno assay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50391131
(CHEMBL2087937)Show SMILES NS(=O)(=O)c1ccc(NN2C(SCC2=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C15H14FN3O3S2/c16-11-3-1-10(2-4-11)15-19(14(20)9-23-15)18-12-5-7-13(8-6-12)24(17,21)22/h1-8,15,18H,9H2,(H2,17,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant COX2 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immunoassay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50391128
(CHEMBL2087940)Show InChI InChI=1S/C16H16N2O3S2/c1-23(20,21)14-9-7-13(8-10-14)17-18-15(19)11-22-16(18)12-5-3-2-4-6-12/h2-10,16-17H,11H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immuno assay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50391133
(CHEMBL2087935)Show InChI InChI=1S/C15H15N3O3S2/c16-23(20,21)13-8-6-12(7-9-13)17-18-14(19)10-22-15(18)11-4-2-1-3-5-11/h1-9,15,17H,10H2,(H2,16,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant COX2 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immunoassay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50391127
(CHEMBL2087941)Show SMILES CS(=O)(=O)c1ccc(NN2C(SCC2=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C16H15ClN2O3S2/c1-24(21,22)14-8-6-13(7-9-14)18-19-15(20)10-23-16(19)11-2-4-12(17)5-3-11/h2-9,16,18H,10H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immuno assay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50391130
(CHEMBL2087938)Show SMILES Cc1ccc(cc1)C1SCC(=O)N1Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H17N3O3S2/c1-11-2-4-12(5-3-11)16-19(15(20)10-23-16)18-13-6-8-14(9-7-13)24(17,21)22/h2-9,16,18H,10H2,1H3,(H2,17,21,22) | PDB
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UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immuno assay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50391133
(CHEMBL2087935)Show InChI InChI=1S/C15H15N3O3S2/c16-23(20,21)13-8-6-12(7-9-13)17-18-14(19)10-22-15(18)11-4-2-1-3-5-11/h1-9,15,17H,10H2,(H2,16,20,21) | PDB
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UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immuno assay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50391125
(CHEMBL2087943)Show SMILES Cc1ccc(cc1)C1SCC(=O)N1Nc1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C17H18N2O3S2/c1-12-3-5-13(6-4-12)17-19(16(20)11-23-17)18-14-7-9-15(10-8-14)24(2,21)22/h3-10,17-18H,11H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.05E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immuno assay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50391127
(CHEMBL2087941)Show SMILES CS(=O)(=O)c1ccc(NN2C(SCC2=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C16H15ClN2O3S2/c1-24(21,22)14-8-6-13(7-9-14)18-19-15(20)10-23-16(19)11-2-4-12(17)5-3-11/h2-9,16,18H,10H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
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UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.22E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant COX2 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immunoassay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50029593
(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)Show InChI InChI=1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.05E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description
Inhibition of ovine COX1 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immuno assay |
Eur J Med Chem 57: 59-64 (2012)
Article DOI: 10.1016/j.ejmech.2012.08.046
BindingDB Entry DOI: 10.7270/Q28C9XBZ |
More data for this
Ligand-Target Pair | |
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