Found 27 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395945
(CHEMBL2164565)Show SMILES CCN(CCO)C(=O)c1cc2cccnn2c1-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C19H18F3N3O2/c1-2-24(9-10-26)18(27)16-12-15-7-4-8-23-25(15)17(16)13-5-3-6-14(11-13)19(20,21)22/h3-8,11-12,26H,2,9-10H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395964
(CHEMBL2164882)Show InChI InChI=1S/C20H22N2O2/c1-3-21(11-12-23)20(24)18-14-17-9-4-5-10-22(17)19(18)16-8-6-7-15(2)13-16/h4-10,13-14,23H,3,11-12H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395956
(CHEMBL2164877)Show SMILES OC[C@@H]1CCCN1C(=O)c1cc2cccnn2c1-c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C20H18F3N3O2/c21-20(22,23)14-5-1-4-13(10-14)18-17(11-15-6-2-8-24-26(15)18)19(28)25-9-3-7-16(25)12-27/h1-2,4-6,8,10-11,16,27H,3,7,9,12H2/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395944
(CHEMBL2164571)Show InChI InChI=1S/C19H21N3O2/c1-3-21(10-11-23)19(24)17-13-16-8-5-9-20-22(16)18(17)15-7-4-6-14(2)12-15/h4-9,12-13,23H,3,10-11H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 251 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395947
(CHEMBL2164886)Show SMILES COc1cccc(c1)-c1c(cc2ccccn12)C(=O)N1CCCCC1CO Show InChI InChI=1S/C22H24N2O3/c1-27-19-10-6-7-16(13-19)21-20(14-17-8-2-4-11-23(17)21)22(26)24-12-5-3-9-18(24)15-25/h2,4,6-8,10-11,13-14,18,25H,3,5,9,12,15H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395961
(CHEMBL2164566)Show SMILES CCN(CCO)C(=O)c1oc2cccnc2c1-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C19H17F3N2O3/c1-2-24(9-10-25)18(26)17-15(16-14(27-17)7-4-8-23-16)12-5-3-6-13(11-12)19(20,21)22/h3-8,11,25H,2,9-10H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395962
(CHEMBL2164885)Show SMILES CCN(CCO)C(=O)c1cc2ccccn2c1-c1cccc(n1)C(F)(F)F Show InChI InChI=1S/C19H18F3N3O2/c1-2-24(10-11-26)18(27)14-12-13-6-3-4-9-25(13)17(14)15-7-5-8-16(23-15)19(20,21)22/h3-9,12,26H,2,10-11H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395954
(CHEMBL2164880)Show SMILES CCN(CCO)C(=O)c1cc2c(C)ccnn2c1-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C20H20F3N3O2/c1-3-25(9-10-27)19(28)16-12-17-13(2)7-8-24-26(17)18(16)14-5-4-6-15(11-14)20(21,22)23/h4-8,11-12,27H,3,9-10H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395953
(CHEMBL2164561)Show SMILES CCN(CCO)C(=O)c1cc2ccc(C)nn2c1-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C20H20F3N3O2/c1-3-25(9-10-27)19(28)17-12-16-8-7-13(2)24-26(16)18(17)14-5-4-6-15(11-14)20(21,22)23/h4-8,11-12,27H,3,9-10H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395949
(CHEMBL2164883)Show InChI InChI=1S/C20H22N2O3/c1-3-21(11-12-23)20(24)18-14-16-8-4-5-10-22(16)19(18)15-7-6-9-17(13-15)25-2/h4-10,13-14,23H,3,11-12H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395960
(CHEMBL2164567)Show SMILES CCN(CCO)C(=O)c1cc2cccnc2n1-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C19H18F3N3O2/c1-2-24(9-10-26)18(27)16-11-13-5-4-8-23-17(13)25(16)15-7-3-6-14(12-15)19(20,21)22/h3-8,11-12,26H,2,9-10H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395948
(CHEMBL2164884)Show InChI InChI=1S/C19H21N3O3/c1-3-21(11-12-23)19(24)15-13-14-7-4-5-10-22(14)18(15)16-8-6-9-17(20-16)25-2/h4-10,13,23H,3,11-12H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395959
(CHEMBL2163359)Show InChI InChI=1S/C19H21N3O3/c1-3-21(10-11-23)19(24)17-13-15-7-5-9-20-22(15)18(17)14-6-4-8-16(12-14)25-2/h4-9,12-13,23H,3,10-11H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395955
(CHEMBL2164879)Show SMILES OC[C@H]1CCCN1C(=O)Cc1cc2cccnn2c1-c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C21H20F3N3O2/c22-21(23,24)16-5-1-4-14(10-16)20-15(11-17-6-2-8-25-27(17)20)12-19(29)26-9-3-7-18(26)13-28/h1-2,4-6,8,10-11,18,28H,3,7,9,12-13H2/t18-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395963
(CHEMBL2164881)Show InChI InChI=1S/C20H22N2O2/c1-2-11-21(13-14-23)20(24)18-15-17-10-6-7-12-22(17)19(18)16-8-4-3-5-9-16/h3-10,12,15,23H,2,11,13-14H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395958
(CHEMBL2164572)Show SMILES CCN(CCO)C(=O)c1cc2cccnn2c1-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H18F3N3O2/c1-2-24(10-11-26)18(27)16-12-15-4-3-9-23-25(15)17(16)13-5-7-14(8-6-13)19(20,21)22/h3-9,12,26H,2,10-11H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395950
(CHEMBL2164564)Show SMILES COc1ccc(cc1)-c1c(cc2cccnn12)C(=O)N1CCC[C@H]1CO |r| Show InChI InChI=1S/C20H21N3O3/c1-26-17-8-6-14(7-9-17)19-18(12-15-4-2-10-21-23(15)19)20(25)22-11-3-5-16(22)13-24/h2,4,6-10,12,16,24H,3,5,11,13H2,1H3/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395946
(CHEMBL2164887)Show InChI InChI=1S/C22H21N3O2/c23-14-16-6-5-7-17(12-16)21-20(13-18-8-1-3-10-24(18)21)22(27)25-11-4-2-9-19(25)15-26/h1,3,5-8,10,12-13,19,26H,2,4,9,11,15H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395952
(CHEMBL2164562)Show SMILES CCN(CCO)C(=O)c1cc2cc(C)cnn2c1-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C20H20F3N3O2/c1-3-25(7-8-27)19(28)17-11-16-9-13(2)12-24-26(16)18(17)14-5-4-6-15(10-14)20(21,22)23/h4-6,9-12,27H,3,7-8H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395951
(CHEMBL2164563)Show SMILES CCN(CCO)C(=O)c1cc2cc(OC)cnn2c1-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C20H20F3N3O3/c1-3-25(7-8-27)19(28)17-11-15-10-16(29-2)12-24-26(15)18(17)13-5-4-6-14(9-13)20(21,22)23/h4-6,9-12,27H,3,7-8H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50395957
(CHEMBL2164573)Show SMILES CCN(CCO)C(=O)c1cc2cccnn2c1Cc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C20H20F3N3O2/c1-2-25(9-10-27)19(28)17-13-16-7-4-8-24-26(16)18(17)12-14-5-3-6-15(11-14)20(21,22)23/h3-8,11,13,27H,2,9-10,12H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50395945
(CHEMBL2164565)Show SMILES CCN(CCO)C(=O)c1cc2cccnn2c1-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C19H18F3N3O2/c1-2-24(9-10-26)18(27)16-12-15-7-4-8-23-25(15)17(16)13-5-3-6-14(11-13)19(20,21)22/h3-8,11-12,26H,2,9-10H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of human ERG expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50395946
(CHEMBL2164887)Show InChI InChI=1S/C22H21N3O2/c23-14-16-6-5-7-17(12-16)21-20(13-18-8-1-3-10-24(18)21)22(27)25-11-4-2-9-19(25)15-26/h1,3,5-8,10,12-13,19,26H,2,4,9,11,15H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of human ERG expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50395944
(CHEMBL2164571)Show InChI InChI=1S/C19H21N3O2/c1-3-21(10-11-23)19(24)17-13-16-8-5-9-20-22(16)18(17)15-7-4-6-14(2)12-15/h4-9,12-13,23H,3,10-11H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of human ERG expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50395947
(CHEMBL2164886)Show SMILES COc1cccc(c1)-c1c(cc2ccccn12)C(=O)N1CCCCC1CO Show InChI InChI=1S/C22H24N2O3/c1-27-19-10-6-7-16(13-19)21-20(14-17-8-2-4-11-23(17)21)22(26)24-12-5-3-9-18(24)15-25/h2,4,6-8,10-11,13-14,18,25H,3,5,9,12,15H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of human ERG expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50395948
(CHEMBL2164884)Show InChI InChI=1S/C19H21N3O3/c1-3-21(11-12-23)19(24)15-13-14-7-4-5-10-22(14)18(15)16-8-6-9-17(20-16)25-2/h4-10,13,23H,3,11-12H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of human ERG expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50395949
(CHEMBL2164883)Show InChI InChI=1S/C20H22N2O3/c1-3-21(11-12-23)20(24)18-14-16-8-4-5-10-22(16)19(18)15-7-6-9-17(13-15)25-2/h4-10,13-14,23H,3,11-12H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of human ERG expressed in CHO cells by IonWorks assay |
Bioorg Med Chem Lett 22: 6888-95 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.059
BindingDB Entry DOI: 10.7270/Q26W9C63 |
More data for this
Ligand-Target Pair | |
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