Affinity Data by PubMed id=23084278

PubMed code 23084278

Found 21 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50279106 (4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one \| ...) Show SMILES O=c1ccc2c(OCCCCOc3ccccc3)c3ccoc3cc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50098785 (4-Benzhydryloxymethyl-1-[3-(4-methoxy-phenyl)-prop...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401661 (CHEMBL2205330) Show SMILES OC1CCN(CCC(C#N)(c2ccccc2)c2ccccc2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401666 (CHEMBL2205325) Show SMILES CCOC(=O)C1(CCN(CCCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401668 (CHEMBL2205323) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401664 (CHEMBL2205327) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401662 (CHEMBL2205329) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401665 (CHEMBL2205326) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401671 (CHEMBL2205320) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401670 (CHEMBL2205321) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401663 (CHEMBL2205328) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401672 (DIPHENOXYLATE) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401657 (CHEMBL2205334) Show SMILES CC1CCN(CCC(C#N)(c2ccccc2)c2ccccc2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401667 (CHEMBL2205324) Show SMILES N#CC(CCN1CCCCC1)(c1ccccc1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401654 (CHEMBL2205337) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401659 (CHEMBL2205332) Show SMILES OC1CCN(CCC(c2ccccc2)c2ccccc2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401660 (CHEMBL2205331) Show SMILES OC1CCCN(CCC(C#N)(c2ccccc2)c2ccccc2)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401656 (CHEMBL2205335) Show SMILES COC1CCN(CCC(C#N)(c2ccccc2)c2ccccc2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401655 (CHEMBL2205336) Show SMILES NC1CCN(CCC(C#N)(c2ccccc2)c2ccccc2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401658 (CHEMBL2205333) Show SMILES OC1CCN(CCCc2ccccc2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50401669 (CHEMBL2205322) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp method				Bioorg Med Chem Lett 22: 7106-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.080 BindingDB Entry DOI: 10.7270/Q2CV4JXW
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%