Found 4 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Macrophage mannose receptor 1
(Homo sapiens (Human)) | BDBM50399360
(CHEMBL1852052)Show SMILES OC[C@H]1O[C@H](Oc2ccc(cc2Cl)-c2ccc(cc2)C(O)=O)[C@@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C19H19ClO8/c20-12-7-11(9-1-3-10(4-2-9)18(25)26)5-6-13(12)27-19-17(24)16(23)15(22)14(8-21)28-19/h1-7,14-17,19,21-24H,8H2,(H,25,26)/t14-,15-,16+,17+,19+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Basel
Curated by ChEMBL
| Assay Description
Displacement of biotinylated-TM PAA from human MMR after 3 hrs by colorimetry |
J Med Chem 55: 9810-6 (2012)
Article DOI: 10.1021/jm3010338
BindingDB Entry DOI: 10.7270/Q2RV0PT3 |
More data for this
Ligand-Target Pair | |
Macrophage mannose receptor 1
(Homo sapiens (Human)) | BDBM50399361
(CHEMBL2079375)Show SMILES OC[C@H]1O[C@H](Oc2ccc(cc2Cl)-n2ccc3cc(ccc23)C(O)=O)[C@@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C21H20ClNO8/c22-13-8-12(23-6-5-10-7-11(20(28)29)1-3-14(10)23)2-4-15(13)30-21-19(27)18(26)17(25)16(9-24)31-21/h1-8,16-19,21,24-27H,9H2,(H,28,29)/t16-,17-,18+,19+,21+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Basel
Curated by ChEMBL
| Assay Description
Displacement of biotinylated-TM PAA from human MMR after 3 hrs by colorimetry |
J Med Chem 55: 9810-6 (2012)
Article DOI: 10.1021/jm3010338
BindingDB Entry DOI: 10.7270/Q2RV0PT3 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member K
(Homo sapiens (Human)) | BDBM50399360
(CHEMBL1852052)Show SMILES OC[C@H]1O[C@H](Oc2ccc(cc2Cl)-c2ccc(cc2)C(O)=O)[C@@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C19H19ClO8/c20-12-7-11(9-1-3-10(4-2-9)18(25)26)5-6-13(12)27-19-17(24)16(23)15(22)14(8-21)28-19/h1-7,14-17,19,21-24H,8H2,(H,25,26)/t14-,15-,16+,17+,19+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Basel
Curated by ChEMBL
| Assay Description
Displacement of biotinylated-TM PAA from human langerin after 3 hrs by colorimetry |
J Med Chem 55: 9810-6 (2012)
Article DOI: 10.1021/jm3010338
BindingDB Entry DOI: 10.7270/Q2RV0PT3 |
More data for this
Ligand-Target Pair | |
C-type lectin domain family 4 member C
(Homo sapiens (Human)) | BDBM50399362
(CHEMBL1852236)Show SMILES OC[C@H]1O[C@H](Oc2ccc(cc2)-c2ccc(cc2)C(O)=O)[C@@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C19H20O8/c20-9-14-15(21)16(22)17(23)19(27-14)26-13-7-5-11(6-8-13)10-1-3-12(4-2-10)18(24)25/h1-8,14-17,19-23H,9H2,(H,24,25)/t14-,15-,16+,17+,19+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Basel
Curated by ChEMBL
| Assay Description
Displacement of biotinylated-TM PAA from human DLEC after 3 hrs by colorimetry |
J Med Chem 55: 9810-6 (2012)
Article DOI: 10.1021/jm3010338
BindingDB Entry DOI: 10.7270/Q2RV0PT3 |
More data for this
Ligand-Target Pair | |
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