Affinity Data by PubMed id=23138692

PubMed code 23138692

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glucose-1-phosphate thymidylyltransferase (Pseudomonas aeruginosa)	BDBM93083 (Analogue of 1a, 8a) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews					Assay Description Inhibition assay using glucose-1-phosphate thymidylyltransferase (RmlA).				ACS Chem Biol 8: 387-96 (2013) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q26D5RMP
University of St. Andrews					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucose-1-phosphate thymidylyltransferase (Pseudomonas aeruginosa)	BDBM93086 (Analogue of 1a, 8b) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews					Assay Description Inhibition assay using glucose-1-phosphate thymidylyltransferase (RmlA).				ACS Chem Biol 8: 387-96 (2013) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q26D5RMP
University of St. Andrews					More data for this Ligand-Target Pair
Glucose-1-phosphate thymidylyltransferase (Pseudomonas aeruginosa)	BDBM93093 (Analogue of 1a, 8t) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews					Assay Description Inhibition assay using glucose-1-phosphate thymidylyltransferase (RmlA).				ACS Chem Biol 8: 387-96 (2013) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q26D5RMP
University of St. Andrews					More data for this Ligand-Target Pair
Glucose-1-phosphate thymidylyltransferase (Pseudomonas aeruginosa)	BDBM93090 (Analogue of 1a, 8j) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews					Assay Description Inhibition assay using glucose-1-phosphate thymidylyltransferase (RmlA).				ACS Chem Biol 8: 387-96 (2013) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q26D5RMP
University of St. Andrews					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucose-1-phosphate thymidylyltransferase (Pseudomonas aeruginosa)	BDBM93091 (Analogue of 1a, 8k) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews					Assay Description Inhibition assay using glucose-1-phosphate thymidylyltransferase (RmlA).				ACS Chem Biol 8: 387-96 (2013) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q26D5RMP
University of St. Andrews					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucose-1-phosphate thymidylyltransferase (Pseudomonas aeruginosa)	BDBM93080 (Analogue of 1a, 1) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews					Assay Description Inhibition assay using glucose-1-phosphate thymidylyltransferase (RmlA).				ACS Chem Biol 8: 387-96 (2013) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q26D5RMP
University of St. Andrews					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucose-1-phosphate thymidylyltransferase (Pseudomonas aeruginosa)	BDBM93092 (Analogue of 1a, 8p) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	387	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews					Assay Description Inhibition assay using glucose-1-phosphate thymidylyltransferase (RmlA).				ACS Chem Biol 8: 387-96 (2013) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q26D5RMP
University of St. Andrews					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucose-1-phosphate thymidylyltransferase (Pseudomonas aeruginosa)	BDBM93081 (Analogue of 1a, 2) Show SMILES Nc1c(O)n(Cc2ccccc2)c(=O)[nH]c1=O Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews					Assay Description Inhibition assay using glucose-1-phosphate thymidylyltransferase (RmlA).				ACS Chem Biol 8: 387-96 (2013) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q26D5RMP
University of St. Andrews					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucose-1-phosphate thymidylyltransferase (Pseudomonas aeruginosa)	BDBM93085 (Analogue of 1a, 15a) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews					Assay Description Inhibition assay using glucose-1-phosphate thymidylyltransferase (RmlA).				ACS Chem Biol 8: 387-96 (2013) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q26D5RMP
University of St. Andrews					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucose-1-phosphate thymidylyltransferase (Pseudomonas aeruginosa)	BDBM93089 (Analogue of 1a, 12b) Show SMILES CCNc1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews					Assay Description Inhibition assay using glucose-1-phosphate thymidylyltransferase (RmlA).				ACS Chem Biol 8: 387-96 (2013) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q26D5RMP
University of St. Andrews					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucose-1-phosphate thymidylyltransferase (Pseudomonas aeruginosa)	BDBM93082 (Analogue of 1a, 5) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews					Assay Description Inhibition assay using glucose-1-phosphate thymidylyltransferase (RmlA).				ACS Chem Biol 8: 387-96 (2013) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q26D5RMP
University of St. Andrews					More data for this Ligand-Target Pair
Glucose-1-phosphate thymidylyltransferase (Pseudomonas aeruginosa)	BDBM93087 (Analogue of 1a, 8c) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews					Assay Description Inhibition assay using glucose-1-phosphate thymidylyltransferase (RmlA).				ACS Chem Biol 8: 387-96 (2013) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q26D5RMP
University of St. Andrews					More data for this Ligand-Target Pair
Glucose-1-phosphate thymidylyltransferase (Pseudomonas aeruginosa)	BDBM52313 (6-amino-1-benzyl-5-(methylamino)pyrimidine-2,4-dio...) Show SMILES CNc1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews					Assay Description Inhibition assay using glucose-1-phosphate thymidylyltransferase (RmlA).				ACS Chem Biol 8: 387-96 (2013) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q26D5RMP
University of St. Andrews					More data for this Ligand-Target Pair
Glucose-1-phosphate thymidylyltransferase (Pseudomonas aeruginosa)	BDBM93084 (Analogue of 1a, 8f) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews					Assay Description Inhibition assay using glucose-1-phosphate thymidylyltransferase (RmlA).				ACS Chem Biol 8: 387-96 (2013) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q26D5RMP
University of St. Andrews					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%