Affinity Data by PubMed id=23167691

PubMed code 23167691

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50156760 ((E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.01E+4	n/a	n/a	n/a	n/a	n/a	25
San Francisco State University Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT1 using Arg-His-Lys-Lys(epsilon-acetyl)-AMC at room temperature for 45 mins by fluorescent screening assay				J Nat Prod 75: 2193-9 (2012) Article DOI: 10.1021/np300640g BindingDB Entry DOI: 10.7270/Q2TH8NWS
San Francisco State University Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50156760 ((E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
San Francisco State University Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT2 using Arg-His-Lys-Lys(epsilon-acetyl)-AMC at 37 degC for 45 mins by fluorescent screening assay				J Nat Prod 75: 2193-9 (2012) Article DOI: 10.1021/np300640g BindingDB Entry DOI: 10.7270/Q2TH8NWS
San Francisco State University Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50403018 (CHEMBL2207877) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70E+6	n/a	n/a	n/a	n/a	n/a	25
San Francisco State University Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT1 using Arg-His-Lys-Lys(epsilon-acetyl)-AMC at room temperature for 45 mins by fluorescent screening assay				J Nat Prod 75: 2193-9 (2012) Article DOI: 10.1021/np300640g BindingDB Entry DOI: 10.7270/Q2TH8NWS
San Francisco State University Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50403018 (CHEMBL2207877) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
San Francisco State University Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT2 using Arg-His-Lys-Lys(epsilon-acetyl)-AMC at 37 degC for 45 mins by fluorescent screening assay				J Nat Prod 75: 2193-9 (2012) Article DOI: 10.1021/np300640g BindingDB Entry DOI: 10.7270/Q2TH8NWS
San Francisco State University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%