Found 28 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50429222
(CHEMBL2331569)Show SMILES NS(=O)(=O)c1ccc(CCN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1 Show InChI InChI=1S/C14H14N2O6S3/c15-23(17,18)12-7-5-11(6-8-12)9-10-16-24(19,20)13-3-1-2-4-14(13)25(16,21)22/h1-8H,9-10H2,(H2,15,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-1-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
MMDB
PDB
Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-2-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50429224
(CHEMBL2332769)Show SMILES NS(=O)(=O)c1ccc(N2S(=O)(=O)c3ccccc3S2(=O)=O)c(Cl)c1 Show InChI InChI=1S/C12H9ClN2O6S3/c13-9-7-8(22(14,16)17)5-6-10(9)15-23(18,19)11-3-1-2-4-12(11)24(15,20)21/h1-7H,(H2,14,16,17) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-9-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50429225
(CHEMBL2332770)Show SMILES NS(=O)(=O)c1ccc(cc1)N1S(=O)(=O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-7-5-9(6-8-10)14-22(17,18)11-3-1-2-4-12(11)23(14,19)20/h1-8H,(H2,13,15,16) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-9-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50429222
(CHEMBL2331569)Show SMILES NS(=O)(=O)c1ccc(CCN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1 Show InChI InChI=1S/C14H14N2O6S3/c15-23(17,18)12-7-5-11(6-8-12)9-10-16-24(19,20)13-3-1-2-4-14(13)25(16,21)22/h1-8H,9-10H2,(H2,15,17,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-2-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50429223
(CHEMBL2332768)Show SMILES NS(=O)(=O)c1ccc(CN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1 Show InChI InChI=1S/C13H12N2O6S3/c14-22(16,17)11-7-5-10(6-8-11)9-15-23(18,19)12-3-1-2-4-13(12)24(15,20)21/h1-8H,9H2,(H2,14,16,17) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-1-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50429223
(CHEMBL2332768)Show SMILES NS(=O)(=O)c1ccc(CN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1 Show InChI InChI=1S/C13H12N2O6S3/c14-22(16,17)11-7-5-10(6-8-11)9-15-23(18,19)12-3-1-2-4-13(12)24(15,20)21/h1-8H,9H2,(H2,14,16,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-2-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50429223
(CHEMBL2332768)Show SMILES NS(=O)(=O)c1ccc(CN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1 Show InChI InChI=1S/C13H12N2O6S3/c14-22(16,17)11-7-5-10(6-8-11)9-15-23(18,19)12-3-1-2-4-13(12)24(15,20)21/h1-8H,9H2,(H2,14,16,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50429226
(CHEMBL2332771)Show SMILES NS(=O)(=O)c1cccc(c1)N1S(=O)(=O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-5-3-4-9(8-10)14-22(17,18)11-6-1-2-7-12(11)23(14,19)20/h1-8H,(H2,13,15,16) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-1-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50429226
(CHEMBL2332771)Show SMILES NS(=O)(=O)c1cccc(c1)N1S(=O)(=O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-5-3-4-9(8-10)14-22(17,18)11-6-1-2-7-12(11)23(14,19)20/h1-8H,(H2,13,15,16) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-9-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50429222
(CHEMBL2331569)Show SMILES NS(=O)(=O)c1ccc(CCN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1 Show InChI InChI=1S/C14H14N2O6S3/c15-23(17,18)12-7-5-11(6-8-12)9-10-16-24(19,20)13-3-1-2-4-14(13)25(16,21)22/h1-8H,9-10H2,(H2,15,17,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50429224
(CHEMBL2332769)Show SMILES NS(=O)(=O)c1ccc(N2S(=O)(=O)c3ccccc3S2(=O)=O)c(Cl)c1 Show InChI InChI=1S/C12H9ClN2O6S3/c13-9-7-8(22(14,16)17)5-6-10(9)15-23(18,19)11-3-1-2-4-12(11)24(15,20)21/h1-7H,(H2,14,16,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50429224
(CHEMBL2332769)Show SMILES NS(=O)(=O)c1ccc(N2S(=O)(=O)c3ccccc3S2(=O)=O)c(Cl)c1 Show InChI InChI=1S/C12H9ClN2O6S3/c13-9-7-8(22(14,16)17)5-6-10(9)15-23(18,19)11-3-1-2-4-12(11)24(15,20)21/h1-7H,(H2,14,16,17) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-1-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50429225
(CHEMBL2332770)Show SMILES NS(=O)(=O)c1ccc(cc1)N1S(=O)(=O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-7-5-9(6-8-10)14-22(17,18)11-3-1-2-4-12(11)23(14,19)20/h1-8H,(H2,13,15,16) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-1-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50429223
(CHEMBL2332768)Show SMILES NS(=O)(=O)c1ccc(CN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1 Show InChI InChI=1S/C13H12N2O6S3/c14-22(16,17)11-7-5-10(6-8-11)9-15-23(18,19)12-3-1-2-4-13(12)24(15,20)21/h1-8H,9H2,(H2,14,16,17) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-9-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50429227
(CHEMBL2332772)Show SMILES NS(=O)(=O)c1ccccc1N1S(=O)(=O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-6-2-1-5-9(10)14-22(17,18)11-7-3-4-8-12(11)23(14,19)20/h1-8H,(H2,13,15,16) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-1-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50429227
(CHEMBL2332772)Show SMILES NS(=O)(=O)c1ccccc1N1S(=O)(=O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-6-2-1-5-9(10)14-22(17,18)11-7-3-4-8-12(11)23(14,19)20/h1-8H,(H2,13,15,16) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50429225
(CHEMBL2332770)Show SMILES NS(=O)(=O)c1ccc(cc1)N1S(=O)(=O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-7-5-9(6-8-10)14-22(17,18)11-3-1-2-4-12(11)23(14,19)20/h1-8H,(H2,13,15,16) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-2-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50429226
(CHEMBL2332771)Show SMILES NS(=O)(=O)c1cccc(c1)N1S(=O)(=O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-5-3-4-9(8-10)14-22(17,18)11-6-1-2-7-12(11)23(14,19)20/h1-8H,(H2,13,15,16) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-2-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50429224
(CHEMBL2332769)Show SMILES NS(=O)(=O)c1ccc(N2S(=O)(=O)c3ccccc3S2(=O)=O)c(Cl)c1 Show InChI InChI=1S/C12H9ClN2O6S3/c13-9-7-8(22(14,16)17)5-6-10(9)15-23(18,19)11-3-1-2-4-12(11)24(15,20)21/h1-7H,(H2,14,16,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-2-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50429227
(CHEMBL2332772)Show SMILES NS(=O)(=O)c1ccccc1N1S(=O)(=O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-6-2-1-5-9(10)14-22(17,18)11-7-3-4-8-12(11)23(14,19)20/h1-8H,(H2,13,15,16) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-9-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50429226
(CHEMBL2332771)Show SMILES NS(=O)(=O)c1cccc(c1)N1S(=O)(=O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-5-3-4-9(8-10)14-22(17,18)11-6-1-2-7-12(11)23(14,19)20/h1-8H,(H2,13,15,16) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50429225
(CHEMBL2332770)Show SMILES NS(=O)(=O)c1ccc(cc1)N1S(=O)(=O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-7-5-9(6-8-10)14-22(17,18)11-3-1-2-4-12(11)23(14,19)20/h1-8H,(H2,13,15,16) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 83 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-9-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50429222
(CHEMBL2331569)Show SMILES NS(=O)(=O)c1ccc(CCN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1 Show InChI InChI=1S/C14H14N2O6S3/c15-23(17,18)12-7-5-11(6-8-12)9-10-16-24(19,20)13-3-1-2-4-14(13)25(16,21)22/h1-8H,9-10H2,(H2,15,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-9-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50429227
(CHEMBL2332772)Show SMILES NS(=O)(=O)c1ccccc1N1S(=O)(=O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-6-2-1-5-9(10)14-22(17,18)11-7-3-4-8-12(11)23(14,19)20/h1-8H,(H2,13,15,16) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 96 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-2-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
PDB
Article
PubMed
| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase-1-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay |
Bioorg Med Chem 21: 1386-91 (2013)
Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
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