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PubMed code 23395113

Compile data set for download or QSAR
Found 31 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431458
PNG
(CHEMBL2348291)
Show SMILES CS(=O)(=O)NC[C@@H](N)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1 |r|
Show InChI InChI=1S/C16H18I2N2O4S/c1-25(22,23)20-9-11(19)6-10-7-14(17)16(15(18)8-10)24-13-4-2-12(21)3-5-13/h2-5,7-8,11,20-21H,6,9,19H2,1H3/t11-/m0/s1
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n/an/a 1.00E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431459
PNG
(CHEMBL2348290)
Show SMILES N[C@H](CNC(=O)CCN1CCOCC1)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1 |r|
Show InChI InChI=1S/C22H27I2N3O4/c23-19-12-15(13-20(24)22(19)31-18-3-1-17(28)2-4-18)11-16(25)14-26-21(29)5-6-27-7-9-30-10-8-27/h1-4,12-13,16,28H,5-11,14,25H2,(H,26,29)/t16-/m0/s1
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n/an/a 1.20E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431464
PNG
(CHEMBL2348285)
Show SMILES CC(C)NC(=O)N[C@H](CO)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1 |r|
Show InChI InChI=1S/C19H22I2N2O4/c1-11(2)22-19(26)23-13(10-24)7-12-8-16(20)18(17(21)9-12)27-15-5-3-14(25)4-6-15/h3-6,8-9,11,13,24-25H,7,10H2,1-2H3,(H2,22,23,26)/t13-/m0/s1
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n/an/a 1.20E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431461
PNG
(CHEMBL2348288)
Show SMILES CC(C)NC(=O)NC[C@@H](N)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1 |r|
Show InChI InChI=1S/C19H23I2N3O3/c1-11(2)24-19(26)23-10-13(22)7-12-8-16(20)18(17(21)9-12)27-15-5-3-14(25)4-6-15/h3-6,8-9,11,13,25H,7,10,22H2,1-2H3,(H2,23,24,26)/t13-/m0/s1
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n/an/a 1.30E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431467
PNG
(CHEMBL2348305)
Show SMILES N[C@H](CO)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1 |r|
Show InChI InChI=1S/C15H15I2NO3/c16-13-6-9(5-10(18)8-19)7-14(17)15(13)21-12-3-1-11(20)2-4-12/h1-4,6-7,10,19-20H,5,8,18H2/t10-/m0/s1
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n/an/a 1.30E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431460
PNG
(CHEMBL2348289)
Show SMILES N[C@H](CNC(=O)N1CCOCC1)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1 |r|
Show InChI InChI=1S/C20H23I2N3O4/c21-17-10-13(9-14(23)12-24-20(27)25-5-7-28-8-6-25)11-18(22)19(17)29-16-3-1-15(26)2-4-16/h1-4,10-11,14,26H,5-9,12,23H2,(H,24,27)/t14-/m0/s1
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n/an/a 1.40E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431462
PNG
(CHEMBL2348287)
Show SMILES CC(=O)NC[C@@H](N)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1 |r|
Show InChI InChI=1S/C17H18I2N2O3/c1-10(22)21-9-12(20)6-11-7-15(18)17(16(19)8-11)24-14-4-2-13(23)3-5-14/h2-5,7-8,12,23H,6,9,20H2,1H3,(H,21,22)/t12-/m0/s1
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n/an/a 1.50E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431456
PNG
(CHEMBL2348293)
Show SMILES CNC(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Show InChI InChI=1S/C15H12I3NO3/c1-19-14(21)6-8-4-11(17)15(12(18)5-8)22-9-2-3-13(20)10(16)7-9/h2-5,7,20H,6H2,1H3,(H,19,21)
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n/an/a 1.90E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431450
PNG
(CHEMBL2348299)
Show SMILES Oc1ccc(Oc2c(I)cc(CC(=O)N3CCOCC3)cc2I)cc1I
Show InChI InChI=1S/C18H16I3NO4/c19-13-10-12(1-2-16(13)23)26-18-14(20)7-11(8-15(18)21)9-17(24)22-3-5-25-6-4-22/h1-2,7-8,10,23H,3-6,9H2
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n/an/a 2.70E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431465
PNG
(CHEMBL2348284)
Show SMILES COC(=O)N[C@H](CO)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1 |r|
Show InChI InChI=1S/C17H17I2NO5/c1-24-17(23)20-11(9-21)6-10-7-14(18)16(15(19)8-10)25-13-4-2-12(22)3-5-13/h2-5,7-8,11,21-22H,6,9H2,1H3,(H,20,23)/t11-/m0/s1
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n/an/a 2.90E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431445
PNG
(CHEMBL2348304)
Show SMILES Oc1ccc(Oc2c(I)cc(CCC(=O)NCC3CCCO3)cc2I)cc1
Show InChI InChI=1S/C20H21I2NO4/c21-17-10-13(3-8-19(25)23-12-16-2-1-9-26-16)11-18(22)20(17)27-15-6-4-14(24)5-7-15/h4-7,10-11,16,24H,1-3,8-9,12H2,(H,23,25)
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n/an/a 2.90E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431455
PNG
(CHEMBL2348294)
Show SMILES CN(C)C(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Show InChI InChI=1S/C16H14I3NO3/c1-20(2)15(22)7-9-5-12(18)16(13(19)6-9)23-10-3-4-14(21)11(17)8-10/h3-6,8,21H,7H2,1-2H3
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n/an/a 3.10E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM18860
PNG
((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Show SMILES N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O |r|
Show InChI InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1
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n/an/a 3.60E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431466
PNG
(CHEMBL2348306)
Show SMILES CC(=O)N[C@H](CO)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1 |r|
Show InChI InChI=1S/C17H17I2NO4/c1-10(22)20-12(9-21)6-11-7-15(18)17(16(19)8-11)24-14-4-2-13(23)3-5-14/h2-5,7-8,12,21,23H,6,9H2,1H3,(H,20,22)/t12-/m0/s1
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n/an/a 3.70E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431444
PNG
(CHEMBL2348282)
Show SMILES OCCNC(=O)CCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
Show InChI InChI=1S/C17H17I2NO4/c18-14-9-11(1-6-16(23)20-7-8-21)10-15(19)17(14)24-13-4-2-12(22)3-5-13/h2-5,9-10,21-22H,1,6-8H2,(H,20,23)
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n/an/a 6.00E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431463
PNG
(CHEMBL2348286)
Show SMILES CS(=O)(=O)N[C@H](CO)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1 |r|
Show InChI InChI=1S/C16H17I2NO5S/c1-25(22,23)19-11(9-20)6-10-7-14(17)16(15(18)8-10)24-13-4-2-12(21)3-5-13/h2-5,7-8,11,19-21H,6,9H2,1H3/t11-/m0/s1
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n/an/a 6.00E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431468
PNG
(CHEMBL1877304)
Show SMILES N[C@@H](Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1)C(O)=O
Show InChI InChI=1S/C15H13I2NO4/c16-11-5-8(7-13(18)15(20)21)6-12(17)14(11)22-10-3-1-9(19)2-4-10/h1-6,13,19H,7,18H2,(H,20,21)/t13-/m0/s1
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n/an/a 6.30E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431443
PNG
(CHEMBL2348283)
Show SMILES CCOCCNC(=O)CCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
Show InChI InChI=1S/C19H21I2NO4/c1-2-25-10-9-22-18(24)8-3-13-11-16(20)19(17(21)12-13)26-15-6-4-14(23)5-7-15/h4-7,11-12,23H,2-3,8-10H2,1H3,(H,22,24)
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n/an/a 6.50E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431448
PNG
(CHEMBL2348301)
Show SMILES Oc1ccc(Oc2c(I)cc(CC(=O)NS(=O)(=O)c3ccccc3)cc2I)cc1I
Show InChI InChI=1S/C20H14I3NO5S/c21-15-11-13(6-7-18(15)25)29-20-16(22)8-12(9-17(20)23)10-19(26)24-30(27,28)14-4-2-1-3-5-14/h1-9,11,25H,10H2,(H,24,26)
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n/an/a 8.60E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431446
PNG
(CHEMBL2348303)
Show SMILES Oc1ccc(Oc2c(I)cc(CCC(=O)N3CCOCC3)cc2I)cc1
Show InChI InChI=1S/C19H19I2NO4/c20-16-11-13(1-6-18(24)22-7-9-25-10-8-22)12-17(21)19(16)26-15-4-2-14(23)3-5-15/h2-5,11-12,23H,1,6-10H2
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n/an/a 9.70E+3n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431447
PNG
(CHEMBL2348302)
Show SMILES CNC(=O)CCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
Show InChI InChI=1S/C16H15I2NO3/c1-19-15(21)7-2-10-8-13(17)16(14(18)9-10)22-12-5-3-11(20)4-6-12/h3-6,8-9,20H,2,7H2,1H3,(H,19,21)
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n/an/a 1.10E+4n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431449
PNG
(CHEMBL2348300)
Show SMILES CS(=O)(=O)NC(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Show InChI InChI=1S/C15H12I3NO5S/c1-25(22,23)19-14(21)6-8-4-11(17)15(12(18)5-8)24-9-2-3-13(20)10(16)7-9/h2-5,7,20H,6H2,1H3,(H,19,21)
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n/an/a 1.40E+4n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM18864
PNG
(3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]pr...)
Show SMILES OC(=O)CCc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Show InChI InChI=1S/C15H11I3O4/c16-10-7-9(2-3-13(10)19)22-15-11(17)5-8(6-12(15)18)1-4-14(20)21/h2-3,5-7,19H,1,4H2,(H,20,21)
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n/an/a 1.70E+4n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM18862
PNG
(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)
Show SMILES OC(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Show InChI InChI=1S/C14H9I3O4/c15-9-6-8(1-2-12(9)18)21-14-10(16)3-7(4-11(14)17)5-13(19)20/h1-4,6,18H,5H2,(H,19,20)
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n/an/a 2.50E+4n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431457
PNG
(CHEMBL2348292)
Show SMILES OC(=O)CCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
Show InChI InChI=1S/C15H12I2O4/c16-12-7-9(1-6-14(19)20)8-13(17)15(12)21-11-4-2-10(18)3-5-11/h2-5,7-8,18H,1,6H2,(H,19,20)
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n/an/a 3.20E+4n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431454
PNG
(CHEMBL2348295)
Show SMILES CCN(CC)C(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Show InChI InChI=1S/C18H18I3NO3/c1-3-22(4-2)17(24)9-11-7-14(20)18(15(21)8-11)25-12-5-6-16(23)13(19)10-12/h5-8,10,23H,3-4,9H2,1-2H3
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n/an/a>5.00E+4n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431452
PNG
(CHEMBL2348297)
Show SMILES CCCCNC(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Show InChI InChI=1S/C18H18I3NO3/c1-2-3-6-22-17(24)9-11-7-14(20)18(15(21)8-11)25-12-4-5-16(23)13(19)10-12/h4-5,7-8,10,23H,2-3,6,9H2,1H3,(H,22,24)
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n/an/a>5.00E+4n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431453
PNG
(CHEMBL2348296)
Show SMILES Oc1ccc(Oc2c(I)cc(CC(=O)N3CCCCC3)cc2I)cc1I
Show InChI InChI=1S/C19H18I3NO3/c20-14-11-13(4-5-17(14)24)26-19-15(21)8-12(9-16(19)22)10-18(25)23-6-2-1-3-7-23/h4-5,8-9,11,24H,1-3,6-7,10H2
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n/an/a>5.00E+4n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431469
PNG
(CHEMBL1236140)
Show SMILES N[C@@H](Cc1ccc(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O |r|
Show InChI InChI=1S/C15H13I2NO4/c16-10-7-9(2-3-13(10)19)22-14-4-1-8(5-11(14)17)6-12(18)15(20)21/h1-5,7,12,19H,6,18H2,(H,20,21)/t12-/m0/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50301375
PNG
(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
Show SMILES N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O |r|
Show InChI InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
Proliferating cell nuclear antigen


(Homo sapiens (Human))		BDBM50431451
PNG
(CHEMBL2348298)
Show SMILES Oc1ccc(Oc2c(I)cc(CC(=O)Nc3ccccc3)cc2I)cc1I
Show InChI InChI=1S/C20H14I3NO3/c21-15-11-14(6-7-18(15)25)27-20-16(22)8-12(9-17(20)23)10-19(26)24-13-4-2-1-3-5-13/h1-9,11,25H,10H2,(H,24,26)
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n/an/a>5.00E+4n/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...

Bioorg Med Chem 21: 1972-7 (2013)


Article DOI: 10.1016/j.bmc.2013.01.022
BindingDB Entry DOI: 10.7270/Q2JQ12CZ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%